Results 201 to 210 of about 12,949 (236)
Some of the next articles are maybe not open access.
Databases for Plant Phosphoproteomics
2015Phosphorylation is the most studied posttranslational modification involved in signal transduction in stress responses, development, and growth. In the recent years large-scale phosphoproteomic studies were carried out using various model plants and several growth and stress conditions.
Waltraud X, Schulze +2 more
openaire +2 more sources
Phosphoproteome of Cryptococcus neoformans
Journal of Proteomics, 2014Cryptococcus neoformans is an encapsulated pathogenic yeast, which causes life threatening meningitis in immunocompromised individuals. C. neoformans var. grubii is the most prevalent and virulent form among the two varieties of C. neoformans - C. neoformans var. grubii and C. neoformans var. neoformans. The virulence of C.
Selvan, Lakshmi Dhevi N. +10 more
openaire +3 more sources
Phosphoproteomics in photosynthetic organisms
ELECTROPHORESIS, 2014As primarily sessile organisms, photosynthetic species survive in dynamic environments by using elegant signaling pathways to manifest molecular responses to extracellular cues. These pathways exploit phosphorylation of specific amino acids (e.g. serine, threonine, tyrosine), which impact protein structure, function, and localization.
William O, Slade +3 more
openaire +2 more sources
Phosphoproteomics takes it easy
Nature Biotechnology, 2015The EasyPhos pipeline simplifies analysis of phosphorylation-dependent signaling networks at high temporal resolution.
openaire +3 more sources
Illuminating the dark phosphoproteome
Science Signaling, 2019Identifying the targets of “dark” kinases will provide new biological and disease insights.
Elise J. Needham +4 more
openaire +2 more sources
Phosphoproteomics and cancer research
Clinical and Translational Oncology, 2009Protein phosphorylation plays key roles in the regulation of normal and cancer cells. It is a highly dynamic process. Protein kinases are the targets of several new cancer drugs and drug candidates. However, some of the main issues related to new drugs are how they function and the selection of those patients that will likely respond best to a ...
Ashman, Keith, Lopez Villar, Elena
openaire +5 more sources
Phosphoproteome Analysis in Yeast
2003Publisher Summary This chapter describes yeast phosphoproteome analysis using the specific example of the effects of the Reg1p regulatory subunit of Glc7p (PP-1C) on the yeast phosphoproteome. The chapter presents genomics and proteomics linked in order to determine the direct effects of a given gene product.
Rupa, Ray, Timothy A, Haystead
openaire +2 more sources
Analytical strategies for phosphoproteomics
PROTEOMICS, 2009AbstractProtein phosphorylation is a key regulator of cellular signaling pathways. It is involved in most cellular events in which the complex interplay between protein kinases and protein phosphatases strictly controls biological processes such as proliferation, differentiation, and apoptosis.
Thingholm, Tine E +2 more
openaire +2 more sources
2011
The identification of phosphorylation on proteins has become practicable for many laboratories in recent years, largely due to improvements in mass spectrometry (MS) and the development of methods to selectively enrich for phosphorylated peptides and proteins.
Alexandra M E, Jones, Thomas S, Nühse
openaire +2 more sources
The identification of phosphorylation on proteins has become practicable for many laboratories in recent years, largely due to improvements in mass spectrometry (MS) and the development of methods to selectively enrich for phosphorylated peptides and proteins.
Alexandra M E, Jones, Thomas S, Nühse
openaire +2 more sources
Phosphoproteomic Analysis of Peptides
2013Posttranslational modifications represent a major mechanism by which cells control molecular events. Sample preparation is one of the biggest keys in terms of proteomic analysis, and especially when looking at phosphoproteomics. Here we describe two techniques that are used to identify phosphopeptides.
openaire +2 more sources