Results 11 to 20 of about 898 (95)

Longitudinal and Vertical Variations of Dissolved Labile Phosphoric Monoesters and Diesters in the Subtropical North Pacific

open access: yesFrontiers in Microbiology, 2021
The labile fraction of dissolved organic phosphorus (DOP) – predominantly consisting of phosphoric esters – is an important microbial P source in the subtropical oligotrophic ocean. However, unlike phosphate, knowledge for labile DOP is still limited due
T. Yamaguchi   +7 more
semanticscholar   +1 more source

Alkaline Phosphatase: A Reliable Endogenous Partner for Drug Delivery and Diagnostics

open access: yesAdvanced Therapeutics, Volume 5, Issue 2, February 2022., 2022
Alkaline phosphatase has been an endogenous partner for phosphate prodrugs for decades. More recently, it has been utilized as a reliable partner for enzyme‐responsive drug nanocarriers and diagnostic systems constructed from novel phosphate‐functionalized biomaterials.
Bao Le‐Vinh   +4 more
wiley   +1 more source

Strategies of organic phosphorus recycling by soil bacteria: acquisition, metabolism, and regulation

open access: yesEnvironmental Microbiology Reports, Volume 14, Issue 1, Page 3-24, February 2022., 2022
Summary Critical to meeting cellular phosphorus (P) demand, soil bacteria deploy a number of strategies to overcome limitation in inorganic P (Pi) in soils. As a significant contributor to P recycling, soil bacteria secrete extracellular enzymes to degrade organic P (Po) in soils into the readily bioavailable Pi.
Yeonsoo Park   +3 more
wiley   +1 more source

IL1RN and PRRX1 as a Prognostic Biomarker Correlated with Immune Infiltrates in Colorectal Cancer: Evidence from Bioinformatic Analysis

open access: yesInternational Journal of Genomics, Volume 2022, Issue 1, 2022., 2022
The extensive morbidity of colorectal cancer (CRC) and the inferior prognosis of terminal CRC urgently call for reliable prognostic biomarkers. For this, we identified 704 differentially expressed genes (DEGs) by intersecting three datasets, GSE41328, GSE37364, and GSE15960 from Gene Expression Omnibus database, to maximize the accuracy of the results.
Qi Wang   +7 more
wiley   +1 more source

Asymmetric Addition and Cycloaddition Reactions with Ylidene‐Five‐Membered Heterocycles

open access: yesAdvanced Synthesis &Catalysis, Volume 363, Issue 23, Page 5196-5234, December 7, 2021., 2021
Abstract Five‐membered heterocycles bearing an exocyclic double bond have been successfully used as substrates in asymmetric addition and cycloaddition reactions. Ylidene‐heterocycles are attractive substrates due to their high functionalization and the presence of an electrophilic conjugated exocyclic double bound that can participate in nucleophilic ...
Ricardo Torán   +5 more
wiley   +1 more source

Proteomics insights into the Burkholderia cenocepacia phosphorus stress response

open access: yesEnvironmental Microbiology, Volume 23, Issue 9, Page 5069-5086, September 2021., 2021
Summary The Burkholderia cepacia complex is a group of Burkholderia species that are opportunistic pathogens causing high mortality rates in patients with cystic fibrosis. An environmental stress often encountered by these soil‐dwelling and pathogenic bacteria is phosphorus limitation, an essential element for cellular processes.
Holly Shropshire   +4 more
wiley   +1 more source

Tripartite parasitic and symbiotic interactions as a possible mechanism of horizontal gene transfer

open access: yesEcology and Evolution, Volume 11, Issue 11, Page 7018-7028, June 2021., 2021
Halyomorpha halys acquired phospholipase C (PLC) genes from Xenorhabdus through the mechanism of horizontal gene transfer (HGT), likely mediated by a nematode during its parasitizing an insect host. This study revealed that an herbivore might enhance adaptation through gaining genes from an endosymbiont of its parasite in the tripartite parasitic and ...
Chaoyang Zhao   +6 more
wiley   +1 more source

Biocatalysis: Enzymatic Synthesis for Industrial Applications

open access: yesAngewandte Chemie International Edition, Volume 60, Issue 1, Page 88-119, January 4, 2021., 2021
Biocatalysis has developed into a mature technology for chemical and pharmaceutical synthesis as well as other areas where high selectivity and mild reaction conditions are required. This Review highlights recent achievements with a special focus on industrialized applications including the introduction of key performance indicators (KPIs) to judge the
Shuke Wu   +4 more
wiley   +1 more source

Importance of long-range channel Sr displacements for the narrow emission in Sr[Li$_2$Al$_2$O$_2$N$_2$]:Eu$^{2+}$ phosphor [PDF]

open access: yesAdv. Optical Mater. 2021, 2100649, 2020
The recently discovered Sr[Li$_2$Al$_2$O$_2$N$_2$]:Eu$^{2+}$ red phosphor, candidate for the next generation of eco-efficient white light-emitting diodes, exhibits excellent emission spectral position and exceptionally small linewidth. It belongs to the UCr$_4$C$_4$-structure family of phosphors, containing many potential candidates commercial ...
arxiv   +1 more source

Link between allosteric signal transduction and functional dynamics in a multi-subunit enzyme: S-adenosylhomocysteine hydrolase [PDF]

open access: yesJ. Am. Chem. Soc. (2011) vol. 133, 19807-19815, 2011
S-adenosylhomocysteine hydrolase (SAHH), a cellular enzyme that plays a key role in methylation reactions including those required for maturation of viral mRNA, is an important drug target in the discovery of antiviral agents. While targeting the active site is a straightforward strategy of enzyme inhibition, evidences of allosteric modulation of ...
arxiv   +1 more source

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