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Phosphorylation of Alcohols with Phosphoryl Chloride
2009C. E. McKenna +2 more
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Pacritinib abrogates the lupus phenotype in ABIN1[D485N] mice
Lupus Science and Medicine, 2023 Objective The aim of the study was to investigate whether the IRAK1/JAK2/Flt3 inhibitor pacritinib prevents disease development in the lupus-prone ABIN1[D485N] knock-in mouse.Methods ABIN1[D485N] knock-in mice aged 8 weeks were fed for 10 weeks on a diet
Philip Cohen +4 more
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Phosphorylation of Sli15 by Ipl1 is important for proper CPC localization and chromosome stability in Saccharomyces cerevisiae [PDF]
, 2014 The chromosomal passenger complex (CPC) is a key regulator of eukaryotic cell division, consisting of the protein kinase Aurora B/Ipl1 in association with its activator (INCENP/Sli15) and two additional proteins (Survivin/Bir1 and Borealin/Nbl1). Here we
Corbishley, Stephen +5 more
core +10 more sources
IL-15 and PIM kinases direct the metabolic programming of intestinal intraepithelial lymphocytes
Nature Communications, 2021 Intraepithelial lymphocytes (IEL) respond to IL-15 complexed with IL-15Ra but how this intrinsically affects IEL is unclear. Here the authors use proteomics analyses of the main mouse IEL subsets and identify PIM kinases as essential for IEL ...
Olivia J. James +7 more
doaj +1 more source
Wellcome Open Research, 2020 Background: Two recessive mutations in the FAM83G gene, causing A34E and R52P amino acid substitutions in the DUF1669 domain of the PAWS1 protein, are associated with palmoplantar keratoderma (PPK) in humans and dogs respectively.
Kevin Z.L. Wu +9 more
doaj +1 more source