Results 21 to 30 of about 1,252,336 (318)

Phosphorylation by Cdk1 induces Plk1-mediated vimentin phosphorylation during mitosis [PDF]

, 2005
Several kinases phosphorylate vimentin, the most common intermediate filament protein, in mitosis. Aurora-B and Rho-kinase regulate vimentin filament separation through the cleavage furrow-specific vimentin phosphorylation.
Erich A. Nigg, Andreas Uldschmid, Hanisch, Anja, Uldschmid, Andreas, Takashi Oguri, Takai, Yasushi, Tomoya Yamaguchi, Yasushi Takai, Masaki Inagaki, Goto, Hidemasa, Tomoya Yokoyama, Anja Hanisch, Hidemasa Goto, Silljé, Herman, Herman Silljé, Oguri, Takashi, Yamaguchi, Tomoya, Nigg, Erich A., Inagaki, Masaki, Yokoyama, Tomoya   +19 more
core   +1 more source

Phosphorylation of the human topoisomerase II protein [PDF]

, 1992
DNA topoisomerase II is an essential enzyme in eukaryotes and is required for many aspects of DNA metabolism including DNA replication, recombination, chromosome segregation and chromosome condensation.
Fry, A. M., Fry, A.M, Fry, Andrew Mark.
core   +1 more source

Charge environments around phosphorylation sites in proteins [PDF]

, 2008
Background: Phosphorylation is a central feature in many biological processes. Structural analyses have identified the importance of charge-charge interactions, for example mediating phosphorylation-driven allosteric change and protein binding to ...
Kitchen, James, Rebecca E Saunders, Jim Warwicker, Saunders, Rebecca E., Warwicker, Jim, Warwicker, Jim; id_orcid, James Kitchen   +6 more
core   +1 more source

PhosPhAt : the Arabidopsis thaliana phosphorylation site database : an update [PDF]

, 2009
The PhosPhAt database of Arabidopsis phosphorylation sites was initially launched in August 2007. Since then, along with 10-fold increase in database entries, functionality of PhosPhAt (phosphat.mpimp-golm.mpg.de) has been considerably upgraded and re ...
Nagel, Alexander, Jones, A., Kersten, B, Durek, P, Kersten, B., Heazlewood, JL, Heazlewood, J. L., Heazlewood, J., MacLean, D, Nagel, A, Schulze, W. X., Nagel, A., Schmidt, R, Jones, Alexandra M., Schulze, W., Kersten, Birgit, Jones, A, Durek, P., Schmidt, R., MacLean, D., Schulze, WX, MacLean, Daniel   +21 more
core   +1 more source

Insulin-stimulated phosphorylation of endothelial nitric oxide synthase at serine-615 contributes to nitric oxide synthesis [PDF]

, 2009
Insulin stimulates endothelial NO (nitric oxide) synthesis via PKB (protein kinase B)/Akt-mediated phosphorylation and activation of eNOS (endothelial NO synthase) at Ser-1177.
Boyd, Alasdair R., Stuart A. Ritchie, Ian P. Salt, Salt, Ian P., Kohlhaas, Christine F, Yalla, Krishna C, Kohlhaas, Christine F., Boyd, Alasdair R, Krishna C. Yalla, Walsh, Kenneth, Ritchie, Stuart A, John M. C. Connell, Christine F. Kohlhaas, Kenneth Walsh, Ritchie, Stuart A., Connell, John M.C., Connell, John Mc, Salt, Ian P, Alasdair R. Boyd, Yalla, Krishna C.   +19 more
core   +1 more source

Prevention and partial reversion of the lupus phenotype in ABIN1[D485N] mice by an IRAK4 inhibitor

Lupus Science and Medicine, 2021
Objective We have reported previously that the IRAK4 inhibitor PF06426779 given to ubiquitin-binding-defective ABIN1[D485N] mice at 6 weeks of age prevents the major facets of lupus that develop 10 weeks later.
Philip Cohen, Tsvetana Petrova, Sambit K Nanda, Cheryl Scudamore, Stephen W Wright, Vikram R Rao   +5 more
doaj   +1 more source

Erythropoietin-induced serine 727 phosphorylation of STAT3 in erythroid cells is mediated by a MEK-, ERK-, and MSK1-dependent pathway [PDF]

, 2003
Objective. Erythropoietin (EPO) is a key regulator of erythropoiesis, playing a role in both the proliferation and differentiation of erythroid cells.
Eggen, BJL, Vellenga, E, Vellenga, Edo,, Vogelzang, Irma, Eggen, BJL; id_orcid, Vogelzang, Irma,, Wierenga, Albertus T.J., Wierenga, Albertus T.J.,, Eggen, Bart J.L.,   +8 more
core   +1 more source

Multiple UBX proteins reduce the ubiquitin threshold of the mammalian p97-UFD1-NPL4 unfoldase

eLife, 2022
The p97/Cdc48 ATPase and its ubiquitin receptors Ufd1-Npl4 are essential to unfold ubiquitylated proteins in many areas of eukaryotic cell biology.
Ryo Fujisawa, Cristian Polo Rivera, Karim PM Labib   +2 more
doaj   +1 more source

Phosphorylation regulates the assembly of chloroplast import machinery [PDF]

, 2008
Chloroplast function depends on the translocation of cytosolically synthesized precursor proteins into the organelle. The recognition and transfer of most precursor proteins across the outer membrane depend on a membrane inserted complex.
Oreb, Igor-Mislav, Mislav Oreb, Schleiff, Enrico, Oliver Mirus, Mirus, Oliver, Anja Höfle, Enrico Schleiff, Höfle, Anja   +7 more
core   +2 more sources

An Affinity-directed Protein Missile (AdPROM) System for Targeted Destruction of Endogenous Proteins

Bio-Protocol, 2017
We recently reported an Affinity-directed PROtein Missile (AdPROM) system for the targeted proteolysis of endogenous proteins of interest (POI) (Fulcher et al., 2016 and 2017).
Thomas Macartney, Gopal Sapkota, Luke Fulcher   +2 more
doaj   +1 more source