Results 21 to 30 of about 22,858 (260)
Singular Features of Trypanosomatids' Phosphotransferases Involved in Cell Energy Management
Enzyme Research, 2011 Trypanosomatids are responsible for economically important veterinary affections and severe human diseases. In Africa, Trypanosoma brucei causes sleeping sickness or African trypanosomiasis, while in America, Trypanosoma cruzi is the etiological agent of
C. Pereira +3 more
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Late G1 Cell Cycle Molecular Pathways
MedEdPORTAL, 2008 The most critical stage of the cell cycle is the transition point in late G1 where the cell commits to initiating DNA synthesis. Multiple pathways of stimulation and inhibition converge, and it can be difficult for students to comprehend how all these ...
Dan Cushman, Robert Warren
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Journal of Biological Chemistry, 2009 Aminoglycoside 2″-phosphotransferases are clinically important enzymes that cause high levels of resistance to aminoglycoside antibiotics by the organisms that harbor them.
M. Tóth +3 more
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Look and Outlook on Enzyme-Mediated Macrolide Resistance
Frontiers in Microbiology, 2018 Since their discovery in the early 1950s, macrolide antibiotics have been used in both agriculture and medicine. Specifically, macrolides such as erythromycin and azithromycin have found use as substitutes for β-lactam antibiotics in patients with ...
Tolou Golkar +3 more
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Integral membrane lipid phosphatases/phosphotransferases: common structure and diverse functions.
Biochemical Journal, 2005 Phospholipids and sphingolipids play critical roles in signal transduction, intracellular membrane trafficking, and control of cell growth and survival.
Y. J. Sigal, M. McDermott, A. Morris
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Crystal structures of two aminoglycoside kinases bound with a eukaryotic protein kinase inhibitor. [PDF]
PLoS ONE, 2011 Antibiotic resistance is recognized as a growing healthcare problem. To address this issue, one strategy is to thwart the causal mechanism using an adjuvant in partner with the antibiotic.
Desiree H Fong +3 more
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Antibiotics, 2022 Antimicrobials in wastewater promote the emergence of antibiotic resistance, facilitated by selective pressure and transfer of resistant genes. Enteric bacteria belonging to Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, Enterobacter ...
Christopher Mutuku +10 more
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A New Family of Phosphotransferases with a P-loop Motif*
Journal of Biological Chemistry, 2002 In most Gram-positive bacteria, catabolite repression is mediated by a bifunctional enzyme, the histidine-containing protein kinase/phosphatase (HprK/P).
A. Galinier +5 more
semanticscholar +1 more source
Scientific Reports, 2023 The ocular surface (OS) enzymes are of great interest due to their potential for novel ocular drug development. We aimed first to profile and classify the enzymes of the OS to describe major biological processes and pathways that are involved in the ...
Murat Akkurt Arslan +6 more
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Enzymes are enriched in bacterial essential genes.
PLoS ONE, 2011 Essential genes, those indispensable for the survival of an organism, play a key role in the emerging field, synthetic biology. Characterization of functions encoded by essential genes not only has important practical implications, such as in identifying
Feng Gao, Randy Ren Zhang
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