Disruption of Hepatic Insulin Signaling Causes Phospholipid Dysregulation in Mice
Pan et al. demonstrate that disruption of hepatic insulin signaling by insulin receptor (IR) substrate (IRS1/2) deletion led to impaired PI3K‐AKT signaling, causing increased Foxo1 activation and TGF‐β1 expression, which dysregulated the expression of the key enzymes involving phospholipid biosynthesis and remodeling.
Quan Pan +6 more
wiley +1 more source
Restoring susceptibility to aminoglycosides: identifying small molecule inhibitors of enzymatic inactivation. [PDF]
Magaña AJ +7 more
europepmc +1 more source
Draft genome sequences of two <i>Stenotrophomonas</i> sp. isolates obtained from the venom of the tarantula <i>Stichoplastoris elusinus</i> (Araneae: Theraphosidae). [PDF]
Cambronero-Heinrichs JC +4 more
europepmc +1 more source
Characterization of the Phosphotransferase from <i>Bacillus subtilis</i> 1101 That Is Responsible for the Biotransformation of Zearalenone. [PDF]
Wu Y +8 more
europepmc +1 more source
Characterizing the resistome of <i>Escherichia coli</i> isolated from farmed white-tailed deer (<i>Odocoileus virginianus</i>) in Florida, United States. [PDF]
Surphlis AC +12 more
europepmc +1 more source
A minimum catalytic unit for synthesis of InsP6 and 5-PP-InsP5 in Arabidopsis. [PDF]
Whitfield HL +5 more
europepmc +1 more source
Role of Inositol Hexakisphosphate Kinases in Vascular Smooth Muscle Cell Calcification. [PDF]
Bahiraii S +5 more
europepmc +1 more source
Mevalonate kinase deficiency (hyperimmunoglobulin D syndrome) in a Tanzanian girl: a case report. [PDF]
Ngowi E +10 more
europepmc +1 more source
Biosynthesis of the Thiofuranose Core in Albomycin Requires a Versatile Enzyme AbmG That Catalyzes Net Dehydration via Cryptic Phosphorylation. [PDF]
Zheng Z +5 more
europepmc +1 more source
Emergence of a novel high-level tigecycline resistance gene <i>tet</i>(X6) variant coexisting with <i>tet</i>(X2) and two <i>tet</i>(X) copies in a <i>Sphingobacterium</i> sp. [PDF]
Xu Q +7 more
europepmc +1 more source

