Results 41 to 50 of about 12,306 (209)

Multi‐Omics Signatures of Periodontitis and Periodontal Therapy on the Oral and Gut Microbiome

Journal of Periodontal Research, EarlyView.
This multi‐omics study integrates shotgun metagenomics and NMR metabolomics to reveal coordinated microbial and metabolic signatures of periodontitis across the oral–gut axis. Non‐surgical periodontal therapy partially restored ecological and functional balance, supporting oral health as a modifiable driver of systemic microbial homeostasis.
Giacomo Baima, Shareef Dabdoub, Vivek Thumbigere‐Math, Davide Giuseppe Ribaldone, Gian Paolo Caviglia, Leonardo Tenori, Linda Fantato, Alessia Vignoli, Mario Romandini, Ilario Ferrocino, Mario Aimetti   +10 more
wiley   +1 more source

Late Stage Mannan Metabolism in Cellvibrio japonicus Requires the Combined Action of a Mannosyl‐Glucose Phosphorylase and a Mannobiose Epimerase

Molecular Microbiology, EarlyView.
Model for the non‐PTS utilization of manno‐oligosaccharides by Cellvibrio japonicus. The Mgp130A and EpiA enzymes are essential for the utilization of mannose residues. ABSTRACT Manno‐oligosaccharides and their metabolism play important roles in gut health, pharmaceutical development, and renewable chemical production.
Jessica K. Novak, Jeffrey G. Gardner
wiley   +1 more source

Understanding the Bacterial Response to Mycotoxins: The Transcriptomic Analysis of Deoxynivalenol-Induced Changes in Devosia mutans 17-2-E-8

Frontiers in Pharmacology, 2019
Deoxynivalenol (DON) is a major fusarium toxin widely detected in cereal grains. The inadvertent exposure to this fungal secondary-metabolite gives rise to a myriad of adverse health effects including appetite loss, emesis, and suppression of the immune ...
Yousef I. Hassan, Jian Wei He, Dion Lepp, Ting Zhou   +3 more
doaj   +1 more source

Starch synthesis in Brachypodium distachyon endosperm occurs in dynamic, connected amyloplast compartments

New Phytologist, EarlyView.
Summary The morphology of starch granules is a major determinant of the functional and nutritional properties of starch and is highly variable among cereal species. Much of this morphological variation stems from differences in the spatial and temporal patterns of starch granule initiation in amyloplasts during grain development.
Lara Esch, Qi Yang Ngai, Sergio G. Lopez, J. Elaine Barclay, Inmaculada Hernández‐Pinzón, Matthew J. Moscou, David Seung   +6 more
wiley   +1 more source

Optimization of carbon and nitrogen utilization for enhanced photosynthesis, biomass and yield by coexpression of phosphoenolpyruvate carboxylase, aspartate aminotransferase and glutamine synthetase in Brassica juncea

Plant Biotechnology Journal, EarlyView.
Summary Coexpression of genes involved in carbon (C) and nitrogen (N) metabolism offers a promising avenue for improving crop yield. This study investigated the impact of coexpressing phosphoenolpyruvate carboxylase [ZmPEPC (P)], aspartate aminotransferase [GmAspAT (A)] and glutamine synthetase [NtGS (G)] in Brassica juncea to enhance plant yield ...
Mamta, Shiv Shanker Pandey, Anish Kaachra, Sachin Vashisath, Dinesh Kumar, Sanjay Kumar   +5 more
wiley   +1 more source

HIV Glycoprotein Gp120 Impairs Fast Axonal Transport by Activating Tak1 Signaling Pathways

ASN Neuro, 2016
Sensory neuropathies are the most common neurological complication of HIV. Of these, distal sensory polyneuropathy (DSP) is directly caused by HIV infection and characterized by length-dependent axonal degeneration of dorsal root ganglion (DRG) neurons ...
Sarah H. Berth, Nichole Mesnard-Hoaglin, Bin Wang, Hajwa Kim, Yuyu Song, Maria Sapar, Gerardo Morfini, Scott T. Brady   +7 more
doaj   +1 more source

Risk Evaluation and Molecular Characterisation of AtNPR1 Transgenic Citrus Lines Tolerant to Citrus Greening Disease

Plant Biotechnology Journal, EarlyView.
ABSTRACT Citrus greening disease, or Huanglongbing (HLB), has caused devastating losses to citrus production in Florida, with yields declining by over 90% since 2005. Despite extensive efforts, no sustainable solution has been widely effective. Here, transgenic ‘Hamlin’ sweet orange lines engineered to constitutively express the Arabidopsis NPR1 ...
Paula Rios Glusberger, Benjamin Merritt, Cheng Liu, Yu Wang, Janice Zale, Hao Wu, Michel Canton, Michael Braverman, Eric W. Triplett, Zhonglin Mou   +9 more
wiley   +1 more source

Functional Repertoire of Antibiotic Resistance Genes in Antibiotic Manufacturing Effluents and Receiving Freshwater Sediments

Frontiers in Microbiology, 2018
Environments polluted by direct discharges of effluents from antibiotic manufacturing are important reservoirs for antibiotic resistance genes (ARGs), which could potentially be transferred to human pathogens.
Juan J. González-Plaza, Ana Šimatović, Milena Milaković, Ana Bielen, Fabienne Wichmann, Nikolina Udiković-Kolić   +5 more
doaj   +1 more source

An Ustilaginoidea virens Nuclear Effector SCRE7 Inhibits Rice Immunity via Suppressing OsLBD11/12‐Promoted Transcription of OsCPS2

Plant Biotechnology Journal, EarlyView.
ABSTRACT Phytopathogenic fungi secrete a great number of effector proteins into various organelles of host plants and suppress plant immunity through different mechanisms. In this study, we identify SCRE7 as a unique nuclear effector that is essential for U. virens infection.
Chunquan Jiang, Xiaoai Li, Anfei Fang, Yu Fu, Caifeng Li, Haojie Dong, Siwen Yu, Shaoqi Zhang, Dayong Li, Nan Nan, Juan Zhang, Reuben J. Peters, Dan Zhao, Wenxian Sun   +13 more
wiley   +1 more source

Aminoglycoside phosphotransferases proteins structure and mechanism [PDF]

Frontiers in Bioscience, 1999
Aminoglycoside antibiotics constitute an important class of clinically useful drugs which are imperiled by the emergence of resistant organisms. Aminoglycoside resistance in the clinics is primarily due to the presence of modifying enzymes which N-acetylate, O-adenylate or O-phosphorylate the antibiotics.
Wright, G. D., Thompson, Paul R
openaire   +3 more sources