Results 41 to 50 of about 25,251 (292)
Enzymes are enriched in bacterial essential genes.
PLoS ONE, 2011 Essential genes, those indispensable for the survival of an organism, play a key role in the emerging field, synthetic biology. Characterization of functions encoded by essential genes not only has important practical implications, such as in identifying
Feng Gao, Randy Ren Zhang
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Scientific Reports, 2023 The ocular surface (OS) enzymes are of great interest due to their potential for novel ocular drug development. We aimed first to profile and classify the enzymes of the OS to describe major biological processes and pathways that are involved in the ...
Murat Akkurt Arslan +6 more
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Hydrolysis of ATP by Aminoglycoside 3′-Phosphotransferases
Journal of Biological Chemistry, 2006 Aminoglycoside 3′-phosphotransferases (APH(3′)s) are common bacterial resistance enzymes to aminoglycoside antibiotics. These enzymes transfer the γ-phosphoryl group of ATP to the 3′-hydroxyl of the antibiotics, whereby the biological activity of the ...
Choonkeun Kim +4 more
semanticscholar +1 more source
Detoxification and stress response genes expressed in a western North American bumble bee, Bombus huntii (Hymenoptera: Apidae) [PDF]
, 2013 BACKGROUND: The Hunt bumble bee (Bombus huntii Greene, Hymenoptera: Apidae) is a holometabolous, social insect important as a pollinator in natural and agricultural ecosystems in western North America.
Dennis L Welker +3 more
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Primate retinal cones express phosphorylated tau associated with neuronal degeneration yet survive in old age [PDF]
, 2017 Photoreceptor cells have high energy demands and suffer significantly with age. In aged rodents both rods and cones are lost, but in primates there is no evidence for aged cone loss, although their function declines.
Asmaa Aboelnour +44 more
core +2 more sources
Molecules, 2018 Phosphoserine phosphatase (PSP), a member of the haloacid dehalogenase (HAD) superfamily that comprises the vast majority of phosphotransferases, is likely a steady-state regulator of the level of d-serine in the brain.
Dieter Krachtus +2 more
doaj +1 more source
Association of Diet and Antimicrobial Resistance in Healthy U.S. Adults
mBio, 2022 Antimicrobial resistance (AMR) represents a significant source of morbidity and mortality worldwide, with expectations that AMR-associated consequences will continue to worsen throughout the coming decades.
Andrew Oliver +12 more
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An Adaptation To Life In Acid Through A Novel Mevalonate Pathway. [PDF]
, 2016 Extreme acidophiles are capable of growth at pH values near zero. Sustaining life in acidic environments requires extensive adaptations of membranes, proton pumps, and DNA repair mechanisms.
Bowie, James U +3 more
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Glyoxalase I gene deletion mutants of Leishmania donovani exhibit reduced methylglyoxal detoxification. [PDF]
PLoS ONE, 2009 BACKGROUND:Glyoxalase I is a metalloenzyme of the glyoxalase pathway that plays a central role in eliminating the toxic metabolite methyglyoxal. The protozoan parasite Leishmania donovani possesses a unique trypanothione dependent glyoxalase system ...
Swati C Chauhan, Rentala Madhubala
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Ultrasensitivity of the Bacillus subtilis sporulation decision [PDF]
, 2012 Starving Bacillus subtilis cells execute a gene expression program resulting in the formation of stress-resistant spores. Sporulation master regulator, Spo0A, is activated by a phosphorelay and controls the expression of a multitude of genes, including ...
Balazsi +51 more
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