Results 111 to 120 of about 110,959 (369)

Assessing cellular efficacy of bromodomain inhibitors using fluorescence recovery after photobleaching

open access: yesEpigenetics & Chromatin, 2014
BackgroundAcetylation of lysine residues in histone tails plays an important role in the regulation of gene transcription. Bromdomains are the readers of acetylated histone marks, and, consequently, bromodomain-containing proteins have a variety of ...
M. Philpott   +9 more
semanticscholar   +1 more source

Transforming Cancer Diagnosis and Therapy Through Fluorescent Hydrogels: A Review

open access: yesAdvanced Healthcare Materials, EarlyView.
This article reviews fluorescent hydrogel systems for cancer detection, monitoring, and therapy. Mimicking the tumor microenvironment, these hydrogels enable real‐time imaging and targeted drug delivery. The review discusses design strategies, labeling techniques, and applications, highlighting challenges and future opportunities in cancer diagnostics ...
Elahe Masaeli   +2 more
wiley   +1 more source

Molecular counting by photobleaching in protein complexes with many subunits: best practices and application to the cellulose synthesis complex

open access: yesMolecular Biology of the Cell, 2014
Fluorescence photobleaching is used to estimate the number of cellulose synthase subunits in Arabidopsis cellulose synthesis complexes. To overcome challenges with counting many (>10) fluorophores from photobleaching traces, a general set of statistical ...
Yalei Chen   +3 more
semanticscholar   +1 more source

Covalent Organic Frameworks for Photocatalysis

open access: yesAdvanced Materials, EarlyView.
This review provides an overview of recent advances in covalent organic frameworks (COFs) for photocatalysis, focusing on sustainable energy applications like water splitting, hydrogen peroxide generation, and CO2 and N2 reduction. It discusses design principles, structure‐function relationships, challenges in COF photocatalysis, and strategies to ...
Bikash Mishra   +6 more
wiley   +1 more source

Experimental measurement of endocytosis in fungal hyphae. [PDF]

open access: yes, 2018
The present study examines the notion that polarized exocytosis in the tips of growing hyphae creates an excess of plasma membrane and thus the need for its removal by endocytosis.
Bartnicki-Garcia, Salomon   +3 more
core  

State‐of‐the‐Art, Insights, and Perspectives for MOFs‐Nanocomposites and MOF‐Derived (Nano)Materials

open access: yesAdvanced Materials, EarlyView.
Different approaches to MOF‐NP composite formation, such as ship‐in‐a‐bottle, bottle‐around‐the‐ship and in situ one‐step synthesis, are used. Owing to synergistic effects, the advantageous features of the components of the composites are beneficially combined, and their individual drawbacks are mitigated.
Stefanos Mourdikoudis   +6 more
wiley   +1 more source

Mechanochemistry for Metal–Organic Frameworks and Covalent–Organic Frameworks (MOFs, COFs): Methods, Materials, and Mechanisms

open access: yesAdvanced Materials, EarlyView.
An overview is provided of the mechanochemistry of metal‐organic frameworks (MOFs) and covalent‐organic frameworks (COFs), highlighting opportunities and strategies for discovery, synthesis and reactivity studies of these materials. Mechanistic studies and comparisons to the mechanochemistry of organic solids are outlined, showcasing how advances in ...
Joseph M. Marrett   +3 more
wiley   +1 more source

Controlled reduction of photobleaching in DNA origami-gold nanoparticle hybrids.

open access: yesNano letters (Print), 2014
The amount of information obtainable from a fluorescence-based measurement is limited by photobleaching: Irreversible photochemical reactions either render the molecules nonfluorescent or shift their absorption and/or emission spectra outside the working
J. Pellegrotti   +7 more
semanticscholar   +1 more source

Automated Label‐Free Assay for Viral Detection and Inhibitor Screening via Biomembrane‐Functionalized Microelectrode Arrays

open access: yesAdvanced Materials, EarlyView.
A bioelectronic sensor integrating 2D cell membranes with organic microelectrode arrays enables detection of SARS‐CoV‐2 fusion pathways. Natively‐expressed viral receptors promote monitoring of viral entry and screening of antibody‐based inhibitors.
Zixuan Lu   +17 more
wiley   +1 more source

Photobleaching-Insensitive Fluorescence Diagnostics in Skin and Brain Tissue

open access: yesIEEE Photonics Journal, 2011
In this paper, we investigate the possibility of using accurate prediction models for the prediction of protoporphyrin bleaching dynamics to achieve photobleaching-insensitive methods to improve the evaluation of data in an existing clinical fluorescence-
M. Brydegaard   +3 more
doaj   +1 more source

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