Results 121 to 130 of about 110,959 (369)

Phosphatidylserine polarization is required for proper Cdc42 localization and for development of cell polarity. [PDF]

, 2010
We used genetically-encoded fluorescent probes to visualize the distribution of phosphatidylserine (PS) in live S. cerevisiae. The majority of the PS was found to reside in the cytosolic leaflet of the plasma membrane.
Gregory Fairn, Sergio Grinstein
core   +1 more source

Photobleaching Kinetics and Time-Integrated Emission of Fluorescent Probes in Cellular Membranes

Molecules, 2014
Since the pioneering work of Hirschfeld, it is known that time-integrated emission (TiEm) of a fluorophore is independent of fluorescence quantum yield and illumination intensity.
D. Wüstner, Tanja Christensen, Lukasz M. Solanko, D. Sage   +3 more
semanticscholar   +1 more source

Microbubble Shell Stiffness Engineering Enhances Ultrasound Imaging, Drug Delivery, and Sonoporation

Advanced Materials, EarlyView.
 Shell‐engineered poly(alkyl cyanoacrylate) microbubbles with tunable stiffness improve ultrasound imaging and therapy. Adjusting the length of the alkyl chain and the glass transition temperature maintains a narrow microbubble size distribution while enhancing drug loading, sonoporation and the acoustic response.
Roman A. Barmin, MirJavad Moosavifar, Elena Rama, Julia Blöck, Anne Rix, Vladislav S. Petrovskii, Rustam A. Gumerov, Jens Köhler, Michael Pohl, Céline Bastard, Stephan Rütten, Laura Charlton, Vu Ngoc Khiêm, Fabio Domenici, Thomas Lisson, Ekaterina Savina, Rui Zhang, Jasmin Baier, Susanne Koletnik, Vasileios Koutsos, Mikhail Itskov, Gaio Paradossi, Georg Schmitz, Tina Vermonden, Laura De Laporte, Robert Göstl, Andreas Herrmann, Igor I Potemkin, Fabian Kiessling, Twan Lammers, Roger M. Pallares   +30 more
wiley   +1 more source

Image segmentation and separation of spectrally similar dyes in fluorescence microscopy by dynamic mode decomposition of photobleaching kinetics [PDF]

, 2022
Daniel Wüstner
openalex   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Bioorthogonal Photoactivation of 2‐Nitrobenzyl Caged Doxorubicin Anticancer Prodrugs on Gold Nanostars

Advanced Materials, EarlyView.
Bioorthogonal chemistry was applied to intracellularly photoactivate Doxorubicin (Dox) using gold nanostars (AuNSt) and near‐infrared (NIR) light. Two prodrugs were used: one photoactivatable, masked with 2‐nitrobenzyl carbamate (proDox1) and another photolabile, masked with 2‐nitrobenzyl diol (proDox2), which was attached to the AuNSt surface.
Juan José Esteve‐Moreno, Andrea Escudero, Oscar Ferreira Silvestre, José Manuel Terrés, Mónica Gorbe, Eva Garrido, Carlos Renero‐Lecuna, Judith Langer, María Alfonso, Javier Ibañez, Félix Sancenón, Roberto Cao‐Milán, Luis M. Liz‐Marzán, Alba García‐Fernández, Andy Hernández‐Montoto, Ramón Martínez‐Máñez   +15 more
wiley   +1 more source

Challenges of II‐VI and III‐V Blue Quantum Dot Light‐Emitting Diodes

Advanced Materials, EarlyView.
Blue‐emitting electroluminescent quantum dot light‐emitting diodes (QD‐LEDs) face critical challenges that limit their practical application, including short operational lifetimes, low color purity, broad spectral linewidths, and unpredictable transient effects like blinking and positive aging.
Shaun Tan, Jonah R. Horowitz, Oliver J. Tye, Moungi G. Bawendi   +3 more
wiley   +1 more source

Advancements in Cellular Imaging: Expanding Horizons with Innovative Dyes and Techniques

Colorants
Advancements in cellular imaging have significantly enhanced our understanding of membrane potential and Ca2⁺ dynamics, which are crucial for various cellular processes. Voltage-sensitive dyes (VSDs) are pivotal in this field, enabling non-invasive, high-
Payal M. Oak, Akash S. Mali
doaj   +1 more source

THE IMPORTANCE OF A PHOTOSENSITIZER BLEACHING REGISTRATION FOR THE EVALUATION OF MECHANISM OF PREPARATION ACTION ON THE PHOTO-INDUCED HEMOLYSIS

Biomedical Photonics, 2017
The influence of three pharmaceutical preparations on photo-induced lysis (irradiation with light-emitting diode of 653 nm) of human erythrocytes in the presence of photosensitizer radachlorin and also on the quantum yield of radachlorin photobleaching ...
L. V. Galebskaya, I. L. Solovtsova, E. B. Miroshnikova, I. A. Mikhailova, M. E. Sushkin, A. V. Razumny, A. V. Babina, V. A. Fomina   +7 more
doaj   +1 more source

Quantitative Imaging of Protein-Protein Interactions by Multiphoton Fluorescence Lifetime Imaging Microscopy using a Streak camera

, 2003
Fluorescence Lifetime Imaging Microscopy (FLIM) using multiphoton excitation techniques is now finding an important place in quantitative imaging of protein-protein interactions and intracellular physiology.
A. Masuda, B. Herman, Becker, Clayton, Clegg, Cole, Elangovan, French, Gadella, Gerritsen, Harpur, Heya, Konig, Konig, Krishnan, Krishnan, Lakowicz, Mahajan, Neuberth, Oida, Periasamy, R. V. Krishnan, Schonle, Selvin, Squire, Squire, Straub, Sytsma, Szmacinski, Tahara, Tavare, V. E. Centonze, van Zandvoort, Verveer, Verveer, Verveer   +35 more
core   +1 more source