Results 131 to 140 of about 67,193 (339)

Fluorescence photobleaching in cell biology [PDF]

, 1982
Ken Jacobson, Elliot Elson, Dennis E. Koppel, Watt W. Webb   +3 more
openalex   +1 more source

The Disordered Region of ASXL1 Acts as an Auto‐Regulator Through Condensation

Advanced Science, EarlyView.
ASXL1's long IDR encodes an electrostatic “basic platform + acidic brake” that autoregulates condensation. Truncation at a clinical hotspot lifts this brake, forming condensates that retarget BRD2, remodel local chromatin accessibility, and impair neutrophil maturation.
Xiao Fang, Qiwei Li, Wenqing Zhang
wiley   +1 more source

Photobleaching dynamics in small molecule vs. polymer organic photovoltaic blends with 1,7-bis-trifluoromethylfullerene

, 2018
Logan E. Garner, Vinila Nellissery Viswanathan, Dylan H. Arias, Colin P. Brook, Steven T. Christensen, Andrew J. Ferguson, Nikos Kopidakis, Bryon W. Larson, Zbyslaw R. Owczarczyk, Jason Pfeilsticker, Praveen C. Ramamurthy, Steven H. Strauss, Olga V. Boltalina, Wade A. Braunecker   +13 more
openalex   +2 more sources

An Opto‐Actuated Hydrogel for Cell Mechanoactuation and Real‐Time Force Monitoring

Advanced Science, EarlyView.
Researchers developed a mechanoactuated hydrogel interface where nanomachines exert forces on adhesion receptors and allow monitoring of traction force responses in real time. They demonstrate reversible talin recruitment, enhanced F‐actin polymerization, and a reduction in cell traction force when force is locally applied to focal adhesions of ...
Rinku Kumar, Marc A. Fernandez‐Yague, Adrien Bessaguet, Hosoowi Lee, Nicolas Giuseppone, Andrés J. García, Aránzazu del Campo   +6 more
wiley   +1 more source

Biocompatible carbon dots with low-saturation-intensity and high-photobleaching-resistance for STED nanoscopy imaging of the nucleolus and tunneling nanotubes in living cells

Nano Reseach, 2019
Hao Li, S. Ye, Jiaqing Guo, Huibo Wang, Wei Yan, Jun Song, J. Qu   +6 more
semanticscholar   +1 more source

A Self‐Organized Liquid Reaction Container for Cellular Memory

Advanced Science, EarlyView.
How cells restore epigenetic information lost during replication is not known. This work proposes a mechanism based on the formation of biomolecular condensates. These condensates are induced by the chromosome itself and serve as reaction vessels for reconstructing missing epigenetic markers.
Sukanta Mukherjee, Enrico Skoruppa, Holger Merlitz, Jens‐Uwe Sommer, Helmut Schiessel   +4 more
wiley   +1 more source

Photobleaching of retinal pigment epithelium melanosomes reduces their ability to inhibit iron‐induced peroxidation of lipids

, 2006
Andrzej Żądło, Małgorzata Różanowska, Janice M. Burke, Tadeusz Sarna   +3 more
openalex   +2 more sources

Disrupting the Formation of YAP Condensates Promotes the Activation of AMPKα to Inhibit the Progression of Primary Liver Cancer

Advanced Science, EarlyView.
This study systematically investigates the function and molecular mechanisms of YAP phase separation in multiple primary liver cancers. These findings provide novel insights into phase separation‐mediated primary liver cancer development and validate targeted disruption of this process as an effective therapeutic strategy for primary liver cancer ...
Shuang‐Zhou Peng, Jia‐Jia Liang, Yun‐Feng Zhan, Wei‐Xun Wu, Wan‐Li Xu, Xiao‐Kun Zhang, Li‐Jun Cai, Fu‐Quan Jiang   +7 more
wiley   +1 more source

Fluorescence recovery after photobleaching reveals high cycling dynamics of plasma membrane aquaporins in Arabidopsis roots under salt stress [PDF]

, 2011
Doan‐Trung Luu, Alexandre Martinière, Mathias Sorieul, John Runions, Christophe Maurel   +4 more
openalex   +1 more source

Astrocytic PCBP1 Suppresses Ferroptosis to Restore Glutamatergic Homeostasis and Mitigate Stress‐Induced Depression in Male Mice

Advanced Science, EarlyView.
This study demonstrates that polyC‐RNA‐binding protein 1 (PCBP1) in ventral hippocampal astrocytes modulates depressive‐like behaviors by regulating glutathione peroxidase 4‐mediated ferroptosis and synaptic glutamatergic transmission. PCBP1 overexpression intervention in the chronic unpredictable mild stress model rescues behavioral deficits ...
Jinyu Zhang, Binbin Zhao, Min Jia, Yan Zhao, Ye Lu, Wenyu Xi, Ziyu Zhu, Xiaojuan Gong, Qingyan Ma, Yuan Gao, Yijie Guo, Pan Li, Feng Zhu, Shuguang Wei, Xiancang Ma, Yunpeng Wang   +15 more
wiley   +1 more source