Photocycle of Cyanobacteriochrome TePixJ [PDF]
Abstract Due to the recent advances in X-ray free electron laser techniques, bilin-containing cyanobacteriochrome photoreceptors have become prime targets for the ever-expanding field of time-resolved structural biology. However, to facilitate these challenging studies, it is essential that the time scales of any structural changes ...
Samantha J. O. Hardman +3 more
openaire +5 more sources
A Multi-Scale–Multi-Stable Model for the Rhodopsin Photocycle
We report a multi-scale simulation study of the photocycle of the rhodopsins. The quasi-atomistic representation (“united atoms” UA) of retinal is combined with a minimalist coarse grained (CG, one-bead-per amino acid) representation of the protein, in a
Francesco Tavanti, Valentina Tozzini
doaj +2 more sources
Confinement in crystal lattice alters entire photocycle pathway of the Photoactive Yellow Protein
Protein structural dynamics can be studied by time-resolved crystallography (TRC) and ultrafast transient spectroscopic methods. Here, the authors perform electronic and vibrational transient absorption measurements to characterise the full photocycle of
Patrick E. Konold +7 more
doaj +2 more sources
‘Seeing’ the electromagnetic spectrum: spotlight on the cryptochrome photocycle
Cryptochromes are widely dispersed flavoprotein photoreceptors that regulate numerous developmental responses to light in plants, as well as to stress and entrainment of the circadian clock in animals and humans.
Blanche Aguida +14 more
doaj +2 more sources
Up to 16% Optical Carbon-13 Hyperpolarization of Donor-Acceptor Molecules at 14.1 T. [PDF]
Up to 16% 13C nuclear polarization is achieved using a rationally designed photo‐CIDNP polarizing agent (PA) in magic‐angle‐spinning NMR experiments at 14.1 T. The PA was designed using a combination of theoretical photocycle calculations and magnetic field dependent experiments to identify important new design principles.
Levien M +10 more
europepmc +3 more sources
Multiple Photocycles of Channelrhodopsin [PDF]
Two rhodopsins with intrinsic ion conductance have been identified recently in Chlamydomonas reinhardtii. They were named "channelrhodopsins" ChR1 and ChR2. Both were expressed in Xenopus laevis oocytes, and their properties were studied qualitatively by two electrode voltage clamp techniques. ChR1 is specific for H+, whereas ChR2 conducts Na+, K+, Ca2+
Hegemann, Peter +2 more
openaire +3 more sources
Photocycles of Channelrhodopsin‐2 [PDF]
AbstractRecent developments have used light‐activated channels or transporters to modulate neuronal activity. One such genetically‐encoded modulator of activity, channelrhodopsin‐2 (ChR2), depolarizes neurons in response to blue light. In this work, we first conducted electrophysiological studies of the photokinetics of hippocampal cells expressing ...
K Nikolic +5 more
openaire +3 more sources
Effect of lipid bilayer properties on the photocycle of green proteorhodopsin [PDF]
The significance of specific lipids for proton pumping by the bacterial rhodopsin proteorhodopsin (pR) was studied. To this end, it was examined whether pR preferentially binds certain lipids and whether molecular properties of the lipid environment ...
von Ballmoos, Christoph +19 more
core +5 more sources
Effect of Hydrated Ionic Liquid on Photocycle and Dynamics of Photoactive Yellow Protein
The mechanism by which proteins are solvated in hydrated ionic liquids remains an open question. Herein, the photoexcitation dynamics of photoactive yellow protein dissolved in hydrated choline dihydrogen phosphate (Hy[ch][dhp]) were studied by transient
Utana Umezaki +7 more
doaj +1 more source
Biological Significance of Photoreceptor Photocycle Length: VIVID Photocycle Governs the Dynamic VIVID-White Collar Complex Pool Mediating Photo-adaptation and Response to Changes in Light Intensity. [PDF]
Most organisms on earth sense light through the use of chromophore-bearing photoreceptive proteins with distinct and characteristic photocycle lengths, yet the biological significance of this adduct decay length is neither understood nor has been tested.
Arko Dasgupta +5 more
doaj +1 more source

