Results 21 to 30 of about 5,688 (181)

Single GAF Domain Phytochrome Exhibits a pH‐Dependent Shunt on the Millisecond Timescale

ChemPhysChem, Volume 26, Issue 6, March 15, 2025.
During their light‐induced photocycle, phytochromes can engage in a thermal reversion back to the initially excited state, denoted as a shunt. This study investigates a pH‐dependent shunt transition in the Pfr state of the All2699g1 phytochrome from Nostoc punctiforme using UV/Vis laser flash photolysis and kinetic modeling. The findings suggest a keto‐
Florian Trunk, Lisa Köhler, Tobias Fischer, Wolfgang Gärtner, Chen Song, Chavdar Slavov, Josef Wachtveitl   +6 more
wiley   +1 more source

Stable flies preferentially oviposit on sites offering conspecific eggs with egg‐derived bacterial semiochemicals

Insect Science, EarlyView.
Stable flies preferentially oviposit on sites offering conspecific eggs with egg‐derived airborne semiochemicals. Egg‐borne bacterial symbionts, and Serratia marcescens in particular, produce odorants which attract gravid female flies and elicit oviposition.
Emmanuel Hung, Anya Gould, Stephanie Zaborniak, Caelen Watson, Regine Gries, Sukhmani Kaur, Kyra Stephens, Augustus Negraeff, Ryan Lam, Alpha Hui, Pantea Zamani, Aryan Monfared, Gerhard Gries   +12 more
wiley   +1 more source

Interrelations of M‐intermediates in bacteriorhodopsin photocycle [PDF]

FEBS Letters, 1992
The photocycles of the wild‐type bacteriorhodopsin and the D96N mutant were investigated by the flash‐photolysis technique. The M‐intermediate formation (400 nm) and the L‐intermediate decay (520 nm) were found to be well described by a sum of two exponents (time constants, τ1 = 65 and τ2 = 250 μs) for the wild‐type bR and three exponents (τ1 = 55 μs ...
Drachev, L.A., Kaulen, A.D., Komrakov, A.Yu.   +2 more
openaire   +2 more sources

Sex‐specific differences in mortality and neurocardiac interactions in the Kv1.1 knockout mouse model of sudden unexpected death in epilepsy (SUDEP)

The Journal of Physiology, EarlyView.
Abstract figure legend The Kcna1 knockout mouse model of sudden unexpected death in epilepsy (SUDEP) exhibits sex‐specific differences in SUDEP risk. Female mice exhibit a lower SUDEP risk than males, despite similar seizure characteristics and interictal cardiac function across sexes.
Kelsey Paulhus, Praveen Kumar, Kelly Kneale, T. Noah Hutson, Nicole M. Gautier‐Hall, Deng‐Shan Shiau, Megan Watts, Krystle Trosclair, Hemangini A. Dhaibar, Paari Dominic, Leonidas Iasemidis, Edward Glasscock   +11 more
wiley   +1 more source

Sound offset responses become highly informative in the auditory cortex

The Journal of Physiology, EarlyView.
Abstract figure legend Using large datasets of neural responses to diverse sounds recorded across four stages of the mouse auditory system (depicted and colour‐coded on the left), offset responses occurring after the termination of each sound (time window indicated by the orange shaded area superimposed with activity traces) were characterized and it ...
Charly Lamothe, Sophie Bagur, Etienne Gosselin, Brice Bathellier   +3 more
wiley   +1 more source

Voltage dependence of proton pumping by bacteriorhodopsin mutants with altered lifetime of the m intermediate

, 2013
The light-driven proton pump bacteriorhodopsin (BR) from Halobacterium salinarum is tightly regulated by the [H+] gradient and transmembrane potential.
Friedrich, Thomas, Éva Lörinczi, Sven Geibel, Thomas Friedrich, Geibel, Sven, Bamberg, Ernst, Lörinczi, Èva, Ernst Bamberg   +7 more
core   +1 more source

Photocycle populations with femtosecond excitation of crystalline photoactive yellow protein [PDF]

, 2016
We investigate photocycle excitation of crystalline photoactive yellow protein using femtosecond laser pulses. This work establishes the feasibility and suitable optical excitation conditions to perform femtosecond time resolved X-ray crystallographic ...
Kupitz, C, Tenboer, J, Hutchison, CDM, Moffat, K, Schmidt, M, van Thor, JJ   +5 more
core   +1 more source

NAD replenishment restores mitochondrial function and thermogenesis in the brown adipose tissue of mice with obesity

The Journal of Physiology, EarlyView.
Abstract figure legend A high‐fat diet (HFD) induces brown adipose tissue (BAT) whitening, mitochondrial dysfunction (damaged cristae, fragmentation), reduced NAD+ levels and impaired thermogenesis, leading to lower energy expenditure and metabolic inflexibility.
Renata R. Braga, Matheus B. Rocha, Ana P. Morelli, Raul G. da Costa, Marcelo A. S. Mori, Adelino S. R. da Silva, José R. Pauli, Dennys E. Cintra, Eduardo R. Ropelle   +8 more
wiley   +1 more source

In Vivo Photocycle of the Euglena gracilis Photoreceptor

, 1997
We present the light-induced photocycle of the paraflagellar swelling of Euglena gracilis. The kinetics of this process was reconstructed by sampling its fluorescence emission and switching the excitation light from 365 nm to 436 nm. Stable intermediates
Passarelli, Vincenzo, Barsanti, Laura, Walne, Patricia L., Gualtieri, Paolo   +3 more
core   +1 more source

A deep learning‐enabled toolkit for the 3D segmentation of ventricular cardiomyocytes

The Journal of Physiology, EarlyView.
Abstract figure legend 3D cardiomyocyte segmentation enables comprehensive analyses of myocardial microstructure in health and disease; however, it is technically demanding. We present an open‐source toolkit for this task, which reduces challenges associated with sample preparation, image restoration, segmentation and proofreading.
Joachim Greiner, Fabio Frangiamore, Frédéric Sonak, Josef Madl, Thomas Seidel, Peter Kohl, Eva A. Rog‐Zielinska   +6 more
wiley   +1 more source