Results 31 to 40 of about 3,309 (240)

Analysis of the triplet-state kinetics of a photosensitizer for photoimmunotherapy by fluorescence correlation spectroscopy [PDF]

, 2021
Herein, we evaluated the intersystem crossing quantum yield (Phi(ISC)) of a silicon phthalocyanine derivatized from IRDye700DX (IR700) which is used as a photosensitizer for photoimmunotherapy (PIT), using fluorescence correlation spectroscopy (FCS). The
Tobita, Seiji, Goto, Yuto, Kitamura, Akira, Ogawa, Mikako, Yoshihara, Toshitada, Kinjo, Masataka, Takakura, Hideo   +6 more
core   +1 more source

Near-Infrared Photoimmunotherapy of Cancer [PDF]

Accounts of Chemical Research, 2019
This Account is the first comprehensive review article on the newly developed, photochemistry-based cancer therapy near-infrared (NIR) photoimmunotherapy (PIT). NIR-PIT is a molecularly targeted phototherapy for cancer that is based on injecting a conjugate of a near-infrared, water-soluble, silicon-phthalocyanine derivative, IRdye700DX (IR700), and a ...
Hisataka Kobayashi, Peter L. Choyke
openaire   +2 more sources

Supramolecular cancer photoimmunotherapy based on precise peptide self-assembly design

, 2022
Combinational photoimmunotherapy (PIT) is considered to be an ideal strategy for the treatment of highly recurrent and metastatic cancer, because it can ablate the primary tumor and provide in situ an autologous tumor vaccine to induce the host immune ...
Yan, Xuehai, Zhang, Lu, Liu, Yamei, Chang, Rui   +3 more
core   +1 more source

Gas therapy potentiates aggregation-induced emission luminogen-based photoimmunotherapy of poorly immunogenic tumors through cGAS-STING pathway activation

Nature Communications, 2023
The immunologically “cold” microenvironment of triple negative breast cancer results in resistance to current immunotherapy. Here, we reveal the immunoadjuvant property of gas therapy with cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS ...
Kaiyuan Wang, Yang Li, Xia Wang, Zhi-Jun Zhang, Liping Cao, Xiaoyuan Fan, Bin Wan, Fengxiang Liu, Xuanbo Zhang, Zhonggui He, Yingtang Zhou, Dong Wang, J. Sun, Xiaoyuan Chen   +13 more
semanticscholar   +1 more source

Breaking the selectivity-uptake trade-off of photoimmunoconjugates with nanoliposomal irinotecan for synergistic multi-tier cancer targeting

Journal of Nanobiotechnology, 2020
Background Photoimmunotherapy involves targeted delivery of photosensitizers via an antibody conjugate (i.e., photoimmunoconjugate, PIC) followed by light activation for selective tumor killing.
Barry J. Liang, Michael Pigula, Yan Baglo, Daniel Najafali, Tayyaba Hasan, Huang-Chiao Huang   +5 more
doaj   +1 more source

Extracorporeal photoimmunotherapy-photopheresis

Frontiers in Bioscience, 2009
Extracorporeal photoimmunotherapy-photopheresis (ECP) is an immunomodulatory therapy, which basically consists of separating the patient's leucocyte rich plasma from the red blood cell fraction, followed by extracorporeal administration of a photosensitizer and UVA light prior to reinfusion of the treated cells.
Theresa, Dani, Robert, Knobler
openaire   +2 more sources

Biomaterial-assisted photoimmunotherapy for cancer

Biomaterials Science, 2020
The biomaterials have been well designed as photoabsorbing/sensitizing agents or effective carriers to enhance the photoimmunotherapeutic efficacy and evade their side effects.
Muchao Chen, Qian Chen
openaire   +3 more sources

NEAR-INFRARED PHOTOIMMUNOTHERAPY TARGETING OF CANCER-ASSOCIATED FIBROBLASTS

, 2023
Cancer-associated fibroblasts (CAFs) constitute a prominent cellular component of the tumor stroma, representing a heterogeneous group of activated fibroblasts.
Glabman, Raisa A
core   +1 more source

Triple-Microenvironment Decoding Enables Logic-Unlocked Precision Photoimmunotherapy. [PDF]

Angew Chem Int Ed Engl
Achieving tumor‐specific activation of pyroptosis and ferroptosis holds great promise for cancer immunotherapy, yet current photosensitizers (PSs) capable of such dual induction predominantly operate in an always‐on manner and rely on visible‐light ...
Liu C, Liu Y, Liang S, Jiang Y, Yi H, Diao X, Li N, Zhang B, Yu M, Li R, Okeke MN, Qian K, Ding Q, Gong P, Cheng Z, Xiang C.   +15 more
europepmc   +3 more sources

Gas therapy potentiates aggregation-induced emission luminogen-based photoimmunotherapy of poorly immunogenic tumor through cGAS-STING pathway activation

, 2023
Source data are provided with the article: Gas therapy potentiates aggregation-induced emission luminogen-based photoimmunotherapy of poorly immunogenic tumor through cGAS-STING pathway activation.
Jin Sun (15370444)
core   +1 more source