Results 51 to 60 of about 3,309 (240)

Reversing cold tumors to hot: An immunoadjuvant-functionalized metal-organic framework for multimodal imaging-guided synergistic photo-immunotherapy

Bioactive Materials, 2021
Immunotherapy assays using immunoadjuvants and tumor antigens could greatly increase the survival rates of patients with malignant tumors. As effective carriers, metal-organic frameworks (MOFs) have been widely utilized in cancer therapy due to their ...
Zhijin Fan, Hongxing Liu, Yaohua Xue, Jingyan Lin, Yu Fu, Zhaohua Xia, Dongming Pan, Jian Zhang, Kun Qiao, Zhenzhen Zhang, Yuhui Liao   +10 more
doaj   +1 more source

De Novo Design of Efficient NIR‐II‐Activated Heavy‐Atom‐Free Type‐I Photosensitizer for Anti‐Tumor Photoimmunotherapy

Advances in Materials
Type‐I photosensitizers (PSs) are considered to be efficient agents for overcoming the oxygen‐dependent deficiency of traditional photodynamic therapy (PDT).
Huan Chen, Yu Wang, Zhang-Xin He, Ying-Peng Wan, Chen Cao, Ziwei Lu, Yi-Jian Gao, Xiao Cui, Ka‐Wai Lee, Jihua Tan, Wen-Chang Xu, Yu-Liang Yang, Xi-Liang Li, Yali Wang, Jia-Yang Hou, Sheng-Liang Li, Chun-Sing Lee   +16 more
semanticscholar   +1 more source

CD146‐Targeted Multimodal Image‐Guided Photoimmunotherapy of Melanoma

Advanced Science, 2019
For melanoma resistant to molecularly targeted therapy and immunotherapy, new treatment strategies are urgently needed. A molecularly targeted theranostic pair may thus be of importance, where the diagnostic probe facilitates patient stratification and ...
Weijun Wei, Dawei Jiang, Emily B. Ehlerding, Todd E. Barnhart, Yunan Yang, Jonathan W. Engle, Quan‐Yong Luo, Peng Huang, Weibo Cai   +8 more
doaj   +1 more source

A self-assembling nanoplatform for pyroptosis and ferroptosis enhanced cancer photoimmunotherapy

Light: Science & Applications
The microenvironment of immunosuppression and low immunogenicity of tumor cells has led to unsatisfactory therapeutic effects of the currently developed nanoplatforms.
Zhi-Chao Wang, Yuqi Tang, Qu-Hai Li
semanticscholar   +1 more source

Sequential PDT and PTT Using Dual‐Modal Single‐Walled Carbon Nanohorns Synergistically Promote Systemic Immune Responses against Tumor Metastasis and Relapse

Advanced Science, 2020
Immune responses stimulated by photodynamic therapy (PDT) and photothermal therapy (PTT) are a promising strategy for the treatment of advanced cancer.
Jingxing Yang, Mengfei Hou, Wenshe Sun, Qinghe Wu, Jia Xu, Liqin Xiong, Yimin Chai, Yuxin Liu, Meihua Yu, Haolu Wang, Zhi Ping Xu, Xiaowen Liang, Chunfu Zhang   +12 more
doaj   +1 more source

Functional nanovesicles displaying anti-PD-L1 antibodies for programmed photoimmunotherapy

Journal of Nanobiotechnology, 2022
Background Photoimmunotherapy is one of the most promising strategies in tumor immunotherapies, but targeted delivery of photosensitizers and adjuvants to tumors remains a major challenge.
Hu Chen, Pengfei Zhang, Yesi Shi, Chao Liu, Qianqian Zhou, Yun Zeng, Hongwei Cheng, Qixuan Dai, Xing Gao, Xiaoyong Wang, Gang Liu   +10 more
doaj   +1 more source

Pathological features of residual head and neck cancer after near-infrared photoimmunotherapy: implications of an unfavorable tumor immune microenvironment

Photodiagnosis and Photodynamic Therapy
Purpose: Near-infrared photoimmunotherapy has been approved in Japan for unresectable locally advanced or recurrent head and neck cancer. While this therapy theoretically induces selective necrosis of epidermal growth factor receptor-expressing tumor ...
Takuma Makino, Yasuharu Sato, Asami Nishikori, Yuto Naoi, Mizuo Ando   +4 more
doaj   +1 more source

Additional file 1 of Functional nanovesicles displaying anti-PD-L1 antibodies for programmed photoimmunotherapy

, 2022
Additional file 1: Figure S1. (a) The standard curve of R837 was detected by HPLC; (b) The standard curve of ICG was measured by ultraviolet spectrophotometer; (c) Analysis of drug loading efficiency using nanometer delivery platform. Figure S2.
Gang Liu (11877539), Hu Chen (19500), Pengfei Zhang (32384), Yun Zeng (697507), Hongwei Cheng (327999), Xing Gao (112909), Chao Liu (43092), Yesi Shi (8431875), Xiaoyong Wang (420898), Qianqian Zhou (1442959), Qixuan Dai (8551827)   +10 more
core   +1 more source

Phase Separation, Material State, and Condensate Fate in Mammalian Autophagy

Advanced Science, EarlyView.
ABSTRACT Biomolecular phase separation has emerged as a key organizing principle in macroautophagy (hereafter autophagy). In mammalian cells, phase‐separated condensates not only serve as substrates for selective degradation, but also act as dynamic platforms for cargo recognition, signaling integration, and autophagosome assembly.
Yuanqiang Lin, Mingran Dai, Enyong Dai, Rui Kang, Daniel J. Klionsky, Daolin Tang, Yu Sun, Ningning Lv, Junnan Jiang   +8 more
wiley   +1 more source

Near-Infrared Photoimmunotherapy for Cancers of the Gastrointestinal Tract [PDF]

Digestion, 2020
Background: Cancers of the gastrointestinal (GI) tract are the common leading cause of cancer-related death in the world. Recent advances in cancer therapies such as intensive multidrug chemotherapy and molecular targeted treatment have improved therapeutic efficacy; however, the outcomes are not satisfied.
Tadanobu, Nagaya, Peter L, Choyke, Hisataka, Kobayashi   +2 more
openaire   +2 more sources