Results 61 to 70 of about 3,309 (240)

Regulating Glucose Metabolism with Prodrug Nanoparticles for Promoting Photoimmunotherapy of Pancreatic Cancer

Advanced Science, 2021
The low immunogenicity, insufficient infiltration of T lymphocytes, and dismal response to immune checkpoint blockade therapy pose major difficulties in immunotherapy of pancreatic cancer.
Fang Sun, Qiurong Zhu, Tianliang Li, Madiha Saeed, Zhiai Xu, Feisheng Zhong, Rundi Song, Manxiu Huai, Mingyue Zheng, Cen Xie, Leiming Xu, Haijun Yu   +11 more
doaj   +1 more source

Cutaneous Lymphoma and Antibody-Directed Therapies

Antibodies, 2023
The introduction of monoclonal antibodies such as rituximab to the treatment of cancer has greatly advanced the treatment scenario in onco-hematology. However, the response to these agents may be limited by insufficient efficacy or resistance.
Alvise Sernicola, Christian Ciolfi, Paola Miceli, Mauro Alaibac   +3 more
doaj   +1 more source

Unlocking Long‐Lived Charge‐Separated State in Pentamethine Cyanine Based on Anionic Hofmeister Effect for Photodynamic Immunotherapy

Advanced Science, EarlyView.
Based on the anionic Hofmeister effect, a universal strategy of incorporation of stereo‐π anion BPh4− into a series of Cy5 skeletons to unlock long‐lived charge‐separated states was reported, wherein the weak electronic coupling and low charge recombination driving force hinder the charge recombination process, elevating the oxygen‐independent ROS ...
Xuan Zhao, Lei Jiang, Yingyong Ni, Ting Wang, Junjun Wang, Shengyu Shi, Jianhua Yu, Zhou Lu, Xiaojiao Zhu, Hongping Zhou   +9 more
wiley   +1 more source

Photoimmunotherapy for Managing Recurrent Laryngeal Cancer Cervical Lesions: A Case Report

Case Reports in Oncology, 2022
Photoimmunotherapy (PIT) targets and destroys tumor cells through irradiation with 690-nm red light after the administration of cetuximab sarotalocan sodium, which contains IRDye700DX bound to cetuximab.
Isaku Okamoto, Takuro Okada, Kunihiko Tokashiki, Kiyoaki Tsukahara   +3 more
doaj   +1 more source

Editorial: Combination of photodynamic therapy and immunotherapy to overcome cancer resistance [PDF]

Frontiers in Immunology
Mojtaba Hoseini-Ghahfarokhi, Kolawole A. Olofinsan, Paromita Sarbadhikary, Glory Kah, Precious Earldom Mulaudzi, Precious Earldom Mulaudzi, Kave Moloudi   +6 more
doaj   +2 more sources

Multi-pathway oxidative stress amplification via controllably targeted nanomaterials for photoimmunotherapy of tumors

Journal of Nanobiotechnology
Photoimmunotherapy, which combines phototherapy with immunotherapy, exhibits significantly improved therapeutic effects compared with mono-treatment regimens.
Song Li, Yun-Heng Liu, Xiaokang Zhang, Yu-Rong Liu, Longqing Si, Shaojing Jiang, Ao-Ya Wang, Xukai Che, Jing Chen, Jinghui Hu   +9 more
semanticscholar   +1 more source

Advanced Nanomedicine for High-Risk HPV-Driven Head and Neck Cancer

Viruses, 2022
The incidence of high-risk Human Papillomavirus (HR-HPV)-driven head and neck squamous cell carcinoma (HNSCC) is on the rise globally. HR-HPV-driven HNSCC displays molecular and clinical characteristics distinct from HPV-uninvolved cases.
Qiang Xu, Ye Chen, Yuan Jin, Zhiyu Wang, Haoru Dong, Andreas M. Kaufmann, Andreas E. Albers, Xu Qian   +7 more
doaj   +1 more source

Photo‐responsive carbon dots for pyroptosis‐mediated anti‐tumor application

Responsive Materials, EarlyView.
Photo‐responsive CDs generate ROS to induce tumor cell pyroptosis, thereby stimulating antitumor immunity. Abstract Pyroptosis refers to a kind of lytic programmed cell death, characterized by the release of pro‐inflammatory cytokines during the process. Owing to its immune response stimulation ability, pyroptosis has garnered considerable attention in
Lingyun Li, Xue Wu, Zekun Yan, Jun Wu, Caishi Huang, Songnan Qu   +5 more
wiley   +1 more source

Dual-Function Antibody Conjugate-Enabled Photoimmunotherapy Complements Fluorescence and Photoacoustic Imaging of Head and Neck Cancer Spheroids

, 2023
Several molecular-targeted imaging and therapeutic agents are in clinical trials for image-guided surgery and photoimmunotherapy (PIT) for head and neck cancers.
Allison Sweeney (13009350), Tayyaba Hasan (209080), Stacey Grimaldo-Garcia (12562182), Srivalleesha Mallidi (1342917), Mohammad A. Saad (12562170)   +4 more
core   +1 more source

Real-Time Fluorescence Monitoring System for Optimal Light Dosage in Cancer Photoimmunotherapy

Pharmaceuticals
Background/Objectives: Near-infrared photoimmunotherapy (NIR-PIT) was recently approved for the treatment of unresectable locally advanced or recurrent head and neck cancers in Japan; however, only one clinical dose has been validated in clinical trials,
Hideki Tanaka, Yoshikatsu Koga, Mayumi Sugahara, Hirobumi Fuchigami, Akihiro Ishikawa, Toru Yamaguchi, Akiko Banba, Takeshi Shinozaki, Kazuto Matsuura, Ryuichi Hayashi, Shingo Sakashita, Masahiro Yasunaga, Tomonori Yano   +12 more
doaj   +1 more source