Results 111 to 120 of about 1,927 (190)

Optical Control of Adenosine A3 Receptor Signaling: Towards a Multimodal Phototherapy in Psoriasis?

Frontiers in Immunology, 2022
Francisco Ciruela, Francisco Ciruela, Kenneth A. Jacobson   +2 more
doaj   +1 more source

Recent Progress in Regulating the Activity of Enzymes with Photoswitchable Inhibitors

Molecules
Photoregulation of biomolecules has become crucial tools in chemical biology, because light enables access under mild conditions and with delicate spatiotemporal control. The control of enzyme activity in a reversible way is a challenge. To achieve it, a
Yi Chen
doaj   +1 more source

Illuminating histamine receptor photopharmacology

, 2022
G Protein-coupled receptors (GPCRs) are transmembrane proteins that represent a highly important class of drug targets, being the primary target of about 35% of all marketed drugs. A prime family of GPCRs is the family of histamine receptors consisting of four distinct members named histamine H1 – H4 receptor (H1R-H4R). For further study of the role of
openaire   +1 more source

Towards medical imaging of drug photoactivation: Development of light responsive magnetic resonance imaging and chemical exchange saturation transfer contrast agents

Smart Molecules
In recent years, the use of light to selectively and precisely activate drugs has been developed along the fundamental concepts of photopharmacology.
Ilse M. Welleman, Carlijn L. F. vanBeek, Ioana Belcin, Albert M. Schulte, Rudi A. J. O. Dierckx, Ben L. Feringa, Hendrikus H. Boersma, Wiktor Szymański   +7 more
doaj   +1 more source

Photopharmacology

Indian Journal of Pharmacology, 2017
Sarma, Phulen, Medhi, Bikash
openaire   +3 more sources

Synthesis of red-shifted azobenzene amino acids for solid phase peptide synthesis [PDF]

Treballs Finals de Grau de Farmàcia, Facultat de Farmàcia i Ciències de l'Alimentació, Universitat de Barcelona, 2024. Tutor/a: Xavier Just BaringoUna de les majors preocupacions globals de la salut actuals, és l’aparició i augment de resistències ...
Sánchez Amoròs, César
core  

In vivo photopharmacology of adrenergic receptors

, 2021
Adrenoceptors are ubiquitous and regulate most vital functions in the human body, including heart and respiratory rate, digestion, smooth-muscle contraction, gland secretion, and pupil diameter among others. In addition, adrenergic neurons firing from the locus coeruleus towards different areas of the central nervous system mediate alertness, responses
D. Prischich, A. M. J. Gomila, S. Milla-Navarro, G. Sangüesa, R. Diez-Alarcia, B. Preda, C. Matera, M. Batlle, L. Ramírez, E. Giralt, J. Hernando, E. Guasch, J. J. Meana, P. De la Villa, P. Gorostiza   +14 more
openaire   +2 more sources

A Quantum-Classical Method Applied to Material Design: Photochromic Materials Optimization for Photopharmacology Applications

Intelligent Computing
The integration of quantum chemistry, machine learning, and optimization calculations is expected to accelerate materials discovery by making large chemical spaces amenable to computational study, a challenging task for classical computers. In this study,
Qi Gao, Michihiko Sugawara, Paul D. Nation, Takao Kobayashi, Yu-ya Ohnishi, Hiroyuki Tezuka, Naoki Yamamoto   +6 more
doaj   +1 more source

X-ray luminescent nanocomposite LaF3:Tb/Citr@[Ru(bpy)2(nic)2]2+ as a model targeted delivery system for photopharmacology and photodynamic therapy

Hybrid Advances
The study is devoted to the development of the concept of targeted delivery of pharmacological agents. A nanocomposite (NC) – (LaF3:Tb/Citr@RuBiNic), which is formed by luminescent nanoparticles (ScNPs) – LaF3: Tb/Citr and a photosensitive substance ...
Andrii Kusyak, Alla Petranovska, Oleksandr Shchehlov, Ruslan Kravchuk, Yaroslav Shuba, Petro Gorbyk   +5 more
doaj   +1 more source

Triplet‐Triplet Annihilation Upconversion‐Based Photolysis: Applications in Photopharmacology

Advanced Healthcare Materials
AbstractThe emerging field of photopharmacology is a promising chemobiological methodology for optical control of drug activities that could ultimately solve the off‐target toxicity outside the disease location of many drugs for the treatment of a given pathology.
Klimezak, Maxime, Chaud, Juliane, Brion, Anaïs, Bolze, Frédéric, Frisch, Benoît, Heurtault, Béatrice, Kichler, Antoine, Specht, Alexandre   +7 more
openaire   +2 more sources