Results 91 to 100 of about 2,002 (201)
Bioinspired Light‐Driven Organic Rotary Molecular Systems
ChemistryEurope, Volume 4, Issue 1, January 2026.This review explores the evolution of bioinspired light‐driven rotary molecular systems (RMSs), highlighting the integration of natural chromophore‐based fragments to enhance quantum efficiency, photostability, and biocompatibility. Key strategies to optimize photochemical performance and broaden functional applications are discussed, providing a ...
Lidia Hortigüela, Sara P. Morcillo
wiley +1 more source
Use of styrylbenzothiazole photoswitches in drugs for spatiotemporal control over microtubule-dependent biology [PDF]
, 2021 Thousands of biological processes take place within a single cell, every second of its existence. These processes are meticulously orchestrated and highly regulated in order to guarantee proper functioning and homeostasis within the organism.
Gao, Li
core
Medicinal Research Reviews, Volume 46, Issue 1, Page 238-271, January 2026.ABSTRACT Solute carrier transporters (SLCs) are integral membrane proteins that play pivotal roles in maintaining cellular homeostasis by mediating the transport of a diverse range of substrates across cell membranes. With their involvement in fundamental physiological processes such as nutrient uptake, neurotransmitter signaling, and drug transport ...
Majlen A. Dilweg +3 more
wiley +1 more source
Potent hemithioindigo-based antimitotics photocontrol the microtubule cytoskeleton in cellulo
Beilstein Journal of Organic Chemistry, 2020 Background: Hemithioindigo is a promising molecular photoswitch that has only recently been applied as a photoswitchable pharmacophore for control over bioactivity in cellulo. Uniquely, in contrast to other photoswitches that have been applied to biology,
Alexander Sailer +6 more
doaj +1 more source
Bioinorganic Chemistry and Applications, Volume 2026, Issue 1, 2026.Photoactivation is the stimulation or regulation of a chemical or a chemical process by utilizing light of specific wavelength that corresponds to an absorbance optimum of the agent being used and can penetrate into tissues. In cancer therapy, photoactivatable drugs utilize this phenomenon by allowing the temporal and spatial regulation of their ...
Simon Ngigi Mbugua +2 more
wiley +1 more source
X‐ray controlled release strategy in cancer therapy
BMEMat, Volume 3, Issue 4, December 2025.A comprehensive review on the design principles and current strategies of X‐ray stimulated release systems in cancer therapy, focusing on the X‐ray responsive functional groups and materials as well as discussing the advantages and current challenges of X‐ray controlled release systems in cancer therapy.
Yiling Ruan +5 more
wiley +1 more source
Phototherapy and photopharmacology.
The Yale journal of biology and medicine, 1986 The activation of 8-methoxypsoralen (8-MOP) by long-wavelength ultraviolet A light (UVA, 320-400 nm) induces the formation of interstrand cross-links in DNA. Psoralen plus UVA (PUVA) is widely used in the treatment of psoriasis, a hyperproliferative disease of the skin.
F P, Gasparro, G, Chan, R L, Edelson
openaire +1 more source
A Chemically Stable Photocaged Noradrenaline. [PDF]
ACS Chem NeurosciPhotoactivatable neurotransmitters provide spatiotemporally precise experimenter control over endogenous receptor activation in living tissue. The resulting optical stimulus-neuronal response relationship provides a sensitive assay that can drive ...
Buczynski SA +4 more
europepmc +3 more sources
ACS Infectious Diseases, 2016 Photopharmacological agents exhibit light-dependent biological activity and may have potential in the development of new antimicrobial agents/modalities. Amidohydrolase enzymes homologous to the well-known human histone deacetylases (HDACs) are present in bacteria, including resistant organisms responsible for a significant number of hospital-acquired ...
Weston, CE +6 more
openaire +5 more sources
Building Bridges:the magic of light andthe logic of molecules [PDF]
The inaugural lecture of Prof. Wiktor Szymanski, newly appointed as chair of Medicinal Chemistry, Photopharmacology and Imaging, will focus on building bridges between disciplines, faculties and ideas.
Szymanski, Wiktor
core +1 more source