Results 81 to 90 of about 2,002 (201)
Optogenética y posibles terapias para la retinosis pigmentaria [PDF]
, 2019 La retinosis pigmentaria (RP) es un grupo clínico y genéticamente heterogéneo de trastornos de la retina hereditarios caracterizados por una disfunción progresiva difusa de fotorreceptores predominantemente bastón, con la posterior degeneración de ...
Sansa Fayos, Marc
core
Advanced Healthcare Materials, Volume 15, Issue 8, 23 February 2026.Despite significant efforts in developing novel biomaterials to regenerate tissue, only a few of them have successfully reached clinical use. It has become clear that the next generation of biomaterials must be multifunctional. Smart biomaterials can respond to environmental or external stimuli, interact in a spatial‐temporal manner, and trigger ...
Sonya Ghanavati +12 more
wiley +1 more source
MedComm, Volume 7, Issue 2, February 2026.Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo +11 more
wiley +1 more source
Continuous flow synthesis of azobenzenes via Baeyer–Mills reaction
Beilstein Journal of Organic Chemistry, 2022 Azobenzene, as one of the most prominent molecular switches, is featured in many applications ranging from photopharmacology to information or energy storage.
Jan H. Griwatz +2 more
doaj +1 more source
Development of 4D printing and its performance testing methods
Responsive Materials, Volume 4, Issue 1, February 2026.This paper reviews the molding methods of 4D printing and its applications in various fields, with emphasis on 4D printing performance testing methods. Abstract 4D printing is a cutting‐edge additive manufacturing technology that introduces the time dimension, allowing printed objects to have dynamic, changeable properties, functions or shapes ...
Guiwei Li +8 more
wiley +1 more source
eLifeWe used light-sensitive drugs to identify the brain region-specific role of mGlu5 metabotropic glutamate receptors in the control of pain. Optical activation of systemic JF-NP-26, a caged, normally inactive, negative allosteric modulator (NAM) of mGlu5 ...
Serena Notartomaso +17 more
doaj +1 more source
eLife, 2020 Glutamate delta (GluD) receptors belong to the ionotropic glutamate receptor family, yet they don’t bind glutamate and are considered orphan. Progress in defining the ion channel function of GluDs in neurons has been hindered by a lack of pharmacological
Damien Lemoine +7 more
doaj +1 more source
Angewandte Chemie International Edition, Volume 65, Issue 3, 16 January 2026.We present a photoswitchable peptide conjugate which exhibits isomerism‐dependent self‐assembly: the planar trans‐isomer assembles into well‐ordered nanofibers while the non‐planar cis‐isomer yields disordered aggregates. Our study offers a direct visualization on the effects of structure formation inside living cells.
Julian Link +6 more
wiley +1 more source
Controlling Biological Pathways with Photopharmacology [PDF]
Biophysical Journal, 2016 Light can be used to control biological events with unmatched temporal and spatial precision. A case in point is optogenetics, which relies on natural photoreceptors that employ retinal, flavins or tetrapyrrols as chromophores. Recently, the incorporation of synthetic photoswitches, such as azobenzenes, into naturally “blind” native receptors has been ...
openaire +1 more source
Phototherapy via Modulation of β‐Amyloid in Combating Alzheimer's Disease
AggregateAlzheimer's disease (AD) is one of the most prevalent forms of neurodegenerative disease. Although some controversy exists, β‐amyloid peptide (Aβ) is recognized to play an essential role in the pathophysiology of AD.
Yunhua Zhang +4 more
doaj +1 more source