Results 181 to 190 of about 2,002 (201)
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New challenges for photopharmacology and computational modeling
Trends in Biochemical Sciences, 2022Mous et al. recently reported the molecular mechanism of chloride transport through a light-activated pumping rhodopsin, a key process involved in a range of cellular functions. Their results open exciting new challenges for photopharmacology and computational modeling that should be addressed in the coming years.
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Optofluidic neural interfaces for in vivo photopharmacology
Current Opinion in Pharmacology, 2022Light-sensitive small molecules can be applied to control cell signaling with enhanced spatiotemporal precision, and their accuracy in intact tissues like the brain can be further enhanced by tethering them to genetically encoded protein tags. Coined "photopharmacology," this approach can acutely manipulate neurotransmission through specific receptor ...
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Triplet‐Triplet Annihilation Upconversion‐Based Photolysis: Applications in Photopharmacology
Advanced Healthcare MaterialsAbstractThe emerging field of photopharmacology is a promising chemobiological methodology for optical control of drug activities that could ultimately solve the off‐target toxicity outside the disease location of many drugs for the treatment of a given pathology.
Benoit Frisch +2 more
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ChemInform Abstract: Emerging Targets in Photopharmacology
ChemInform, 2016AbstractReview: 184 refs.
Michael M. Lerch +4 more
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In vivo adrenergic modulation with photopharmacology
2021Adrenoceptors are ubiquitous and regulate most vital functions in the human body, including heart and respiratory rate, digestion, smooth-muscle contraction, gland secretion, and pupil diameter among others. In addition, adrenergic neurons firing from the locus coeruleus towards different areas of the central nervous system mediate alertness, responses
D. Prischich +14 more
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Photopharmacology and Photochemical Biology
ChemPhotoChem, 2021Alexander Deiters +2 more
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Implantable Optofluidic Systems for Wireless In Vivo Photopharmacology
ChemPhotoChem, 2021Raza Qazi, Choong Yeon Kim, Inho Kang
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