Results 41 to 50 of about 64,303 (289)

Photoreceptor cell death, proliferation and formation of hybrid rod/S-cone photoreceptors in the degenerating STK38L mutant retina.

PLoS ONE, 2011
A homozygous mutation in STK38L in dogs impairs the late phase of photoreceptor development, and is followed by photoreceptor cell death (TUNEL) and proliferation (PCNA, PHH3) events that occur independently in different cells between 7-14 weeks of age ...
Ágnes I Berta, Kathleen Boesze-Battaglia, Sem Genini, Orly Goldstein, Paul J O'Brien, Ágoston Szél, Gregory M Acland, William A Beltran, Gustavo D Aguirre   +8 more
doaj   +1 more source

Near‐Infrared Organic Photovoltaic Electrodes for Subretinal Neurostimulation

Advanced Functional Materials, EarlyView.
Organic photovoltaic electrodes based on the D18:Y6 blend enable precise and light‐controlled activation of retinal ganglion cells in a degenerating retina. NIR Light‐driven activation of retinal ganglion cells, tunable stimulation parameters, and biocompatibility with human retinal organoids highlight their potential for next‐generation prosthetics ...
Andrea Corna, Katarina Gugujonovic, Manuela Schiek, Alessandro Bellapianta, Paul Werginz, Amelie Ziller, Markus Clark Scharber, Ahmad Salti, Matthias Bolz, Mihai Irimia‐Vladu, Günther Zeck   +10 more
wiley   +1 more source

Lrit1, a Retinal Transmembrane Protein, Regulates Selective Synapse Formation in Cone Photoreceptor Cells and Visual Acuity

Cell Reports, 2018
Summary: In the vertebrate retina, cone photoreceptors play crucial roles in photopic vision by transmitting light-evoked signals to ON- and/or OFF-bipolar cells.
Akiko Ueno, Yoshihiro Omori, Yuko Sugita, Satoshi Watanabe, Taro Chaya, Takashi Kozuka, Tetsuo Kon, Satoyo Yoshida, Kenji Matsushita, Ryusuke Kuwahara, Naoko Kajimura, Yasushi Okada, Takahisa Furukawa   +12 more
doaj   +1 more source

Upconversion Nanoparticles Embedded Photonic Contact Lens for Transepithelial Corneal Crosslinking Using Hyaluronate – Riboflavin Conjugate

Advanced Functional Materials, EarlyView.
A minimally invasive, transepithelial corneal cross‐linking (TE‐CXL) approach is presented using upconversion nanoparticles (UCNPs)‐loaded contact lenses (UCLs), after topical delivery of hyaluronate–riboflavin conjugates. The NIR‐to‐UV/blue light conversion by UCNPs in a UCL can activate riboflavin for TE‐CXL, resulting in the biomechanical strength ...
Gibum Lee, Inhoo Choi, Anara Molkenova, Yengwoo Son, Seungmin Yang, Mina Kwon, Tae‐Im Kim, Ki Su Kim, Sei Kwang Hahn   +8 more
wiley   +1 more source

The Retinal Pigment Epithelium: a Convenient Source of New Photoreceptor cells?

Journal of Ophthalmic & Vision Research, 2014
Recent success in restoring visual function through photoreceptor replacement in mouse models of photoreceptor degeneration intensifies the need to generate or regenerate photoreceptor cells for the ultimate goal of using cell replacement therapy for ...
Shu-Zhen Wang, Run-Tao Yan
doaj  

Inhibition of the MAPK/c-Jun-EGR1 Pathway Decreases Photoreceptor Cell Death in the rd1 Mouse Model for Inherited Retinal Degeneration [PDF]

, 2022
Yujie Dong, Wenrong Xu, Yan Li, Chunling Wei, Yunzhang Hu, Zhulin Hu, François Paquet‐Durand, Kangwei Jiao   +7 more
openalex   +1 more source

Spectrally Tuned Floating‐Gate Synapse Based on Blue‐ and Red‐Absorbing Organic Molecules for Wavelength‐Selective Neural Networks and Fashion Image Classifications

Advanced Functional Materials, EarlyView.
The characteristics of a vertical floating gate heterostructure transistor device that exhibits neuromorphic potentiation under visible light illumination are investigated. Due to spectrally‐tuned absorbance properties of each thin film layer and introduction of tunneling dielectric, the device enables wavelength‐selective tuning of synaptic plasticity
Seungme Kang, Jisoo Park, Jinwoong Hong, Jinmin Park, Jeongbo Lee, Hyeonjung Kim, Wonjun Shin, Eva Bestelink, Radu A. Sporea, Seyong Oh, Chung Whan Lee, Yun‐Hi Kim, Hocheon Yoo   +12 more
wiley   +1 more source

Characterization and Transplantation of CD73-Positive Photoreceptors Isolated from Human iPSC-Derived Retinal Organoids

Stem Cell Reports, 2018
Summary: Photoreceptor degenerative diseases are a major cause of blindness for which cell replacement is one of the most encouraging strategies. For stem cell-based therapy using human induced pluripotent stem cells (hiPSCs), it is crucial to obtain a ...
Giuliana Gagliardi, Karim Ben M'Barek, Antoine Chaffiol, Amélie Slembrouck-Brec, Jean-Baptiste Conart, Céline Nanteau, Oriane Rabesandratana, José-Alain Sahel, Jens Duebel, Gael Orieux, Sacha Reichman, Olivier Goureau   +11 more
doaj   +1 more source

The Hippo pathway controls a switch between retinal progenitor cell proliferation and photoreceptor cell differentiation in zebrafish. [PDF]

PLoS ONE, 2014
The precise regulation of numbers and types of neurons through control of cell cycle exit and terminal differentiation is an essential aspect of neurogenesis. The Hippo signaling pathway has recently been identified as playing a crucial role in promoting
Yoichi Asaoka, Shoji Hata, Misako Namae, Makoto Furutani-Seiki, Hiroshi Nishina   +4 more
doaj   +1 more source

On the Wrong Track: Alterations of Ciliary Transport in Inherited Retinal Dystrophies

Frontiers in Cell and Developmental Biology, 2021
Ciliopathies are a group of heterogeneous inherited disorders associated with dysfunction of the cilium, a ubiquitous microtubule-based organelle involved in a broad range of cellular functions. Most ciliopathies are syndromic, since several organs whose
Laura Sánchez-Bellver, Laura Sánchez-Bellver, Vasileios Toulis, Vasileios Toulis, Gemma Marfany, Gemma Marfany, Gemma Marfany   +6 more
doaj   +1 more source