Results 31 to 40 of about 107,639 (354)
Phototransduction in ganglion-cell photoreceptors [PDF]
Pflügers Archiv - European Journal of Physiology, 2007 A third class of photoreceptors has recently been identified in the mammalian retina. They are a rare cell type within the class of ganglion cells, which are the output cells of the retina. These intrinsically photosensitive retinal ganglion cells support a variety of physiological responses to daylight, including synchronization of circadian rhythms ...
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Abnormal photoreceptor outer segment development and early retinal degeneration in kif3a mutant zebrafish [PDF]
, 2016 Photoreceptors are highly specialized sensory neurons that possess a modified primary cilium called the outer segment. Photoreceptor outer segment formation and maintenance require highly active protein transport via a process known as intraflagellar ...
Akhtar +44 more
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Retinal gene therapy with a large MYO7A cDNA using adeno-associated virus. [PDF]
, 2013 Usher 1 patients are born profoundly deaf and then develop retinal degeneration. Thus they are readily identified before the onset of retinal degeneration, making gene therapy a viable strategy to prevent their blindness.
Boye, S +8 more
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Photoreceptor cell fate specification in vertebrates [PDF]
Development, 2015 Photoreceptors – the light-sensitive cells in the vertebrate retina – have been extremely well-characterized with regards to their biochemistry, cell biology and physiology. They therefore provide an excellent model for exploring the factors and mechanisms that drive neural progenitors into a differentiated cell fate in the nervous system. As a result,
Joseph A, Brzezinski, Thomas A, Reh
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Photoreceptor Inner Segment Morphology in Best Vitelliform Macular Dystrophy [PDF]
, 2016 PURPOSE To characterize outer retina structure in best vitelliform macular dystrophy (BVMD) and to determine the effect of macular lesions on overlying and adjacent photoreceptors.
Carroll, Joseph +7 more
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STEREOLOGY AND SOME STRUCTURAL CORRELATES OF RETINAL AND PHOTORECEPTOR CELL FUNCTION
Image Analysis and Stereology, 2011 The retina is the part of the eye which detects light, transduces it into nerve impulses and plays a significant role in visual perception. Sensitivity to light is multi-factorial and depends on the properties of photopigment molecules, their synthesis ...
Terry M Mayhew
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Arrestins expressed in killifish photoreceptor cells [PDF]
FEBS Letters, 1997 Two kinds of cDNA fragments (KfhArr‐R and KfhArr‐C) encoding the putative arrestins of killifish,Oryzias latipes, were isolated. The distributions of these transcripts were investigated by in situ hybridization, and it was demonstrated that KfhArr‐R and KfhArr‐C are expressed in, respectively, rod and all four types of cone cells.
Hisatomi, Osamu +3 more
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Early stages of retinal development depend on Sec13 function [PDF]
, 2013 Summary ER-to-Golgi transport of proteins destined for the extracellular space or intracellular compartments depends on the COPII vesicle coat and is constitutive in all translationally active cells.
Cavodeassi, Florencia +3 more
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Role of microglial cells in photoreceptor degeneration
Neural Regeneration Research, 2019 Inherited photoreceptor degeneration in humans constitutes a major cause of irreversible blindness in the world. They comprise various diseases, but retinitis pigmentosa is the most frequently observed. Retinitis pigmentosa is commonly limited to the eye,
Johnny Di Pierdomenico +4 more
doaj +1 more source
Docosahexaenoic acid promotes photoreceptor differentiation without altering Crx expression [PDF]
, 2006 PURPOSE: The precise molecular cues required for photoreceptor development are still unknown. Pax6 and Crx are essential during early retinal development and for photoreceptor differentiation, respectively.
Garelli, Andres +2 more
core +2 more sources