Results 11 to 20 of about 62,604 (264)

Using electroretinograms and multi-model inference to identify spectral classes of photoreceptors and relative opsin expression levels [PDF]

open access: yesPeerJ, 2017
Understanding how individual photoreceptor cells factor in the spectral sensitivity of a visual system is essential to explain how they contribute to the visual ecology of the animal in question.
Nicolas Lessios
doaj   +2 more sources

In vitro transdifferentiation of human peripheral blood mononuclear cells to photoreceptor-like cells

open access: yesBiology Open, 2016
Direct reprogramming is a promising, simple and low-cost approach to generate target cells from somatic cells without using induced pluripotent stem cells.
Yukari Komuta   +7 more
doaj   +1 more source

Insights into the evolutionary origin of the pineal color discrimination mechanism from the river lamprey

open access: yesBMC Biology, 2021
Background Pineal-related organs in cyclostomes, teleosts, amphibians, and reptiles exhibit color opponency, generating antagonistic neural responses to different wavelengths of light and thereby sensory information about its “color”.
Seiji Wada   +5 more
doaj   +1 more source

SARM1 deficiency promotes rod and cone photoreceptor cell survival in a model of retinal degeneration

open access: yesLife Science Alliance, 2020
This study reports that activation of SARM1 causes destruction of NAD pools in photoreceptor cells of the retina and identifies a role for SARM1-dependent photoreceptor cell death in retinal degeneration.
Ema Ozaki   +10 more
doaj   +1 more source

Alterations in kainate receptor and TRPM1 localization in bipolar cells after retinal photoreceptor degeneration

open access: yesFrontiers in Cellular Neuroscience, 2015
Photoreceptor degeneration differentially impacts glutamatergic signaling in downstream On and Off bipolar cells. In rodent models, photoreceptor degeneration leads to loss of glutamatergic signaling in On bipolar cells, whereas Off bipolar cells appear ...
Jacqueline eGayet-Primo   +1 more
doaj   +1 more source

Phototransduction in ganglion-cell photoreceptors [PDF]

open access: yesPflügers Archiv - European Journal of Physiology, 2007
A third class of photoreceptors has recently been identified in the mammalian retina. They are a rare cell type within the class of ganglion cells, which are the output cells of the retina. These intrinsically photosensitive retinal ganglion cells support a variety of physiological responses to daylight, including synchronization of circadian rhythms ...
openaire   +2 more sources

Differentiation of human olfactory mucosa mesenchymal stem cells into photoreceptor cells in vitro [PDF]

open access: yesInternational Journal of Ophthalmology, 2017
AIM: To investigate whether the human olfactory mucosa mesenchymal stem cells (OM-MSCs) can differentiate into photoreceptor cells in vitro. METHODS: Through the olfactory mucosa adherent method, olfactory mucosa was isolated, cultured and identified in
Wen Lu   +4 more
doaj   +1 more source

Chemically-induced photoreceptor degeneration and protection in mouse iPSC-derived three-dimensional retinal organoids

open access: yesStem Cell Research, 2017
Induced pluripotent stem cells (iPSCs), which can be differentiated into various tissues and cell types, have been used for clinical research and disease modeling.
Shin-ichiro Ito   +2 more
doaj   +1 more source

Three distinct roles for notch in Drosophila R7 photoreceptor specification. [PDF]

open access: yesPLoS Biology, 2011
Receptor tyrosine kinases (RTKs) and Notch (N) proteins are different types of transmembrane receptors that transduce extracellular signals and control cell fate.
Andrew Tomlinson   +2 more
doaj   +1 more source

STEREOLOGY AND SOME STRUCTURAL CORRELATES OF RETINAL AND PHOTORECEPTOR CELL FUNCTION

open access: yesImage Analysis and Stereology, 2011
The retina is the part of the eye which detects light, transduces it into nerve impulses and plays a significant role in visual perception. Sensitivity to light is multi-factorial and depends on the properties of photopigment molecules, their synthesis ...
Terry M Mayhew
doaj   +1 more source

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