Results 11 to 20 of about 107,639 (354)

Microfluidic processing of stem cells for autologous cell replacement

Stem Cells Translational Medicine, 2021
Autologous photoreceptor cell replacement is one of the most promising approaches currently under development for the treatment of inherited retinal degenerative blindness.
Nicholas E. Stone, Andrew P. Voigt, Robert F. Mullins, Todd Sulchek, Budd A. Tucker   +4 more
doaj   +1 more source

Histamine Recycling Is Mediated by CarT, a Carcinine Transporter in Drosophila Photoreceptors. [PDF]

PLoS Genetics, 2015
Histamine is an important chemical messenger that regulates multiple physiological processes in both vertebrate and invertebrate animals. Even so, how glial cells and neurons recycle histamine remains to be elucidated.
Ying Xu, Futing An, Jolanta A Borycz, Janusz Borycz, Ian A Meinertzhagen, Tao Wang   +5 more
doaj   +1 more source

Pineal photoreceptor cells are required for maintaining the circadian rhythms of behavioral visual sensitivity in zebrafish.

PLoS ONE, 2012
In non-mammalian vertebrates, the pineal gland functions as the central pacemaker that regulates the circadian rhythms of animal behavior and physiology. We generated a transgenic zebrafish line [Tg(Gnat2:gal4-VP16/UAS:nfsB-mCherry)] in which the E. coli
Xinle Li, Jake Montgomery, Wesley Cheng, Jung Hyun Noh, David R Hyde, Lei Li   +5 more
doaj   +1 more source

Sphingolipids as emerging mediators in retina degeneration [PDF]

, 2019
The sphingolipids ceramide (Cer), sphingosine-1-phosphate (S1P), sphingosine (Sph), and ceramide-1-phosphate (C1P) are key signaling molecules that regulate major cellular functions.
Prado Spalm, Facundo Heber, Rotstein, Nora Patricia, Simon, Maria Victoria, Vera, Marcela Sonia   +3 more
core   +1 more source

Role of Oxidative Stress in Retinal Photoreceptor Cell Death in N-Methyl-N-nitrosourea–Treated Mice

Journal of Pharmacological Sciences, 2012
This study aimed to investigate whether oxidative stress contributes to retinal cell death in a mouse model of photoreceptor degeneration induced by N-methyl-N-nitrosourea (MNU).
Kazuhiro Tsuruma, Mika Yamauchi, Yuta Inokuchi, Sou Sugitani, Masamitsu Shimazawa, Hideaki Hara   +5 more
doaj   +1 more source

Using electroretinograms and multi-model inference to identify spectral classes of photoreceptors and relative opsin expression levels [PDF]

PeerJ, 2017
Understanding how individual photoreceptor cells factor in the spectral sensitivity of a visual system is essential to explain how they contribute to the visual ecology of the animal in question.
Nicolas Lessios
doaj   +2 more sources

Cis-regulatory basis of sister cell type divergence in the vertebrate retina [PDF]

, 2019
Multicellular organisms evolved via repeated functional divergence of transcriptionally related sister cell types, but the mechanisms underlying sister cell type divergence are not well understood.
Corbo, Joseph C, Hughes, Andrew E.O., Lawrence, Karen A, Murphy, Daniel P, Myers, Connie A   +4 more
core   +3 more sources

Neural superposition and oscillations in the eye of the blowfly [PDF]

, 1987
Neural superposition in the eye of the blowfly Calliphora erythrocephala was investigated by stimulating single photoreceptors using corneal neutralization through water immersion.
D Burkhardt, H Reuter, H Reuter, J Scholes, JH Hateren van, K Kirschfeld, N Franceschini, NH Sabah, PG Lillywhite, RS Lewis, SB Laughlin, SB Laughlin, SR Shaw, SR Shaw, SR Shaw, T Matic, V Braitenberg, V Braitenberg, W Reichardt   +18 more
core   +2 more sources

Ceramide is a Mediator of Apoptosis in Retina Photoreceptors [PDF]

, 2006
PURPOSE. The precise mechanisms involved in photoreceptor apoptosis are still unclear. We here investigated the role of ceramide, a sphingolipid precursor that induces apoptosis upon cellular stress, in activating this death in photoreceptors.
Abrahan, Carolina Elizabeth, German, Olga Lorena, Miranda, Gisela Edit, Rotstein, Nora Patricia   +3 more
core   +1 more source

In vitro transdifferentiation of human peripheral blood mononuclear cells to photoreceptor-like cells

Biology Open, 2016
Direct reprogramming is a promising, simple and low-cost approach to generate target cells from somatic cells without using induced pluripotent stem cells.
Yukari Komuta, Toshiyuki Ishii, Makoto Kaneda, Yasuji Ueda, Kiyoko Miyamoto, Masashi Toyoda, Akihiro Umezawa, Yuko Seko   +7 more
doaj   +1 more source