Results 51 to 60 of about 4,871,943 (300)

Direct Conversion of Mouse Fibroblasts into Photoreceptor-like Cells

Cells
The purpose of our study is to explore the potential of a transcription factor-based strategy for directly converting mouse fibroblasts into photoreceptor-like cells.
Jia Xie, Sam Enayati, Dong Feng Chen, Jianwei Jiao, Liu Yang   +4 more
doaj   +1 more source

COCO enhances the efficiency of photoreceptor precursor differentiation in early human embryonic stem cell-derived retinal organoids

Stem Cell Research & Therapy, 2020
Background Significant progress has been made in cell replacement therapy for neural retinal diseases using retinal cells differentiated from human pluripotent stem cells.
Deng Pan, Xi-Xi Xia, Heng Zhou, Si-Qian Jin, Yang-Yan Lu, Hui Liu, Mei-Ling Gao, Zi-Bing Jin   +7 more
doaj   +1 more source

Functional identification of an opsin kinase underlying inactivation of the pineal bistable opsin parapinopsin in zebrafish

Zoological Letters, 2021
In the pineal organ of zebrafish larvae, the bistable opsin parapinopsin alone generates color opponency between UV and visible light. Our previous study suggested that dark inactivation of the parapinopsin photoproduct, which activates G-proteins, is ...
Baoguo Shen, Seiji Wada, Haruka Nishioka, Takashi Nagata, Emi Kawano-Yamashita, Mitsumasa Koyanagi, Akihisa Terakita   +6 more
doaj   +1 more source

High Yield of Cells Committed to the Photoreceptor Fate from Expanded Mouse Retinal Stem Cells

, 2006
The purpose of the present work was to generate, from retinal stem cells (RSCs), a large number of cells committed toward the photoreceptor fate in order to provide an unlimited cell source for neurogenesis and transplantation studies.
Faten Merhi-Soussi, Meriem Tekaya, Dana Hornfeld, Corinne Kostic, Kriss Canola, Brigitte Angénieux, Yvan Arsenijevic, Kostic, C., Angenieux, B., Arsenijevic, Y., Hornfeld, D., Merhi-Soussi, F., Canola, K., Tekaya, M.   +13 more
core   +1 more source

Sub‐1 ms Optoelectronic Synapse Based on {ZnCdO/ZnO} Multilayer Structure for High‐Speed Neuromorphic Vision Systems

Advanced Functional Materials, EarlyView.
Eu‐doped {ZnCdO/ZnO} structures grown on Si are developed, showcasing dual‐functionality controlled by europium doping. While high europium concentration transforms the device into an ultrafast, self‐powered photodetector, low‐doped structures can be used as an optoelectronic synapse.
Igor Perlikowski, Eunika Zielony, Adrian Kaim, Ewa Przeździecka   +3 more
wiley   +1 more source

The Retinal Pigment Epithelium: a Convenient Source of New Photoreceptor cells?

Journal of Ophthalmic & Vision Research, 2014
Recent success in restoring visual function through photoreceptor replacement in mouse models of photoreceptor degeneration intensifies the need to generate or regenerate photoreceptor cells for the ultimate goal of using cell replacement therapy for ...
Shu-Zhen Wang, Run-Tao Yan
doaj  

Does GDNF exert its neuroprotective effects on photoreceptors in the rd1 retina through the glial glutamate transporter GLAST? [PDF]

, 2005
PURPOSE: We previously demonstrated that exogenous glial cell line-derived neurotrophic factor (GDNF) induces histological and functional protection of photoreceptors in the retinal degeneration (rd1) mouse model.
Neveux, N, Leveillard, T, Sahel, JA, Simonutti, M, Delyfer, MN   +4 more
core  

Global Transcriptional and Epigenetic Reconfiguration during Chemical Reprogramming of Human Retinal Pigment Epithelial Cells into Photoreceptor-like Cells

Cells, 2022
Retinal degenerative diseases are frequently caused by the loss of retinal neural cells such as photoreceptors. Cell replacement is regarded as one of the most promising therapies.
Xiaoqian Deng, Ryan Lee, Sin Yee Lim, Zheng Zhong, Jing Wang, Yizhi Liu, Guoping Fan   +6 more
doaj   +1 more source

Loss of Dmp18 does not affect the differentiation of photoreceptor cells.

, 2022
(A-A”) The differentiation of photoreceptor cells was not affected by Dmp18 deletion. The Elav was expressed in the Dmp18 mutant clones in the eye disc. GFP-free region marked the Dmp18 mutant clones.
Zhiqing Lin (496540), Shenfei Sun (4405684), Xue Lin (2050762), Yan Zhang (8098), Xiaolei Ye (288556), Yun Qi (560401), Lixiu Lv (13871280), Yi Lin (49406), Xinhua Lin (538781), Ying Feng (151159)   +9 more
core   +1 more source

Material Coupling in Hybrid Neuromorphic Devices: From Fundamentals to System‐Level Applications

Advanced Functional Materials, EarlyView.
Hybrid neuromorphic devices utilize heterointerfaces between emerging semiconductors, where charge transfer and trapping, ion or defect modulation, and photogating are translated into synaptic functions. This paper discusses coupling strategies that tailor interfacial electronic and ionic properties in organic semiconductors, metal oxides, two ...
Minsu So, Sunwoo Jeong, Youngmin Han, Fabrizio Torricelli, Hocheon Yoo, Junhwan Choi   +5 more
wiley   +1 more source