Results 201 to 210 of about 78,413 (264)

Functional development of photoreceptors in human retinal organoids. [PDF]

open access: yesStem Cell Res Ther
Zhang Y   +7 more
europepmc   +1 more source

Kcnv2 E151X Mouse Captures Hallmarks of KCNV2‐Associated Retinal Dystrophy

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background KCNV2‐associated retinopathy is a rare inherited retinal dystrophy caused by variants in the KCNV2 gene, leading to disrupted photoreceptor behaviour and progressive deterioration of vision. Patients have characteristic electroretinography abnormalities, including reduced cone response, delayed and reduced rod response to low light ...
Nermina Xhaferri   +3 more
wiley   +1 more source

Visualization Guidelines for the Control Room: An Evaluation of Visual Alert Encoding with Domain Experts

open access: yesComputer Graphics Forum, EarlyView.
Abstract Visualization is routinely used in control rooms to maintain situational awareness of complex sociotechnical systems. While control room design often incorporates human factors engineering to identify the information presented, it is not unusual for control room visual encodings to rely closely on operator experience and historical encodings ...
P. Baudains   +3 more
wiley   +1 more source

Single-cell analysis reveals impaired Müller glia-mediated intercellular communication and photoreceptor pathology in USH1C retinal organoids. [PDF]

open access: yesCell Mol Life Sci
Wenck N   +16 more
europepmc   +1 more source

Zeb2 Controls Retinal Physiological and Pathological Angiogenesis by Regulating Astrocyte Proliferation and Differentiation

open access: yesCell Proliferation, EarlyView.
During development, the oxygen‐sensitive transcription factor Zeb2 restrains astrocyte proliferation and maturation to ensure balanced retinal angiogenesis. In disease, it promotes the neurotoxic A1 astrocyte phenotype and inflammation, thereby promoting reparative revascularization over pathological neovascularization.
Jing Liu   +5 more
wiley   +1 more source

Redox regulation of PDE6 and cGMP signaling in diabetic retinal neurodegeneration. [PDF]

open access: yesBiochem Biophys Rep
Perez-Martinez CJ   +9 more
europepmc   +1 more source

Rethinking diabetic retinopathy: Homeostatic mechanisms for retinal clearance

open access: yesDiabetic Medicine, EarlyView.
In the healthy retina, balanced production and clearance of metabolic waste and fluid maintain retinal homeostasis and normal visual function. Diabetes disrupts this balance, increasing the accumulation of metabolic waste products, including advanced glycation end products (AGEs) and advanced lipoxidation end products (ALEs), while impairing waste and ...
Karis Little   +7 more
wiley   +1 more source

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