Research progress on glycolytic reprogramming in ophthalmic diseases. [PDF]
Gong X +9 more
europepmc +1 more source
Techniques for subretinal injections in animals
Abstract Subretinal injections are not commonly performed during clinical treatment of animals but are frequently used in laboratory animal models to assess therapeutic efficacy and safety of gene and cell therapy products. Veterinary ophthalmologists are often employed to perform the injections in the laboratory animal setting, due to knowledge of ...
Ryan F. Boyd, Simon M. Petersen‐Jones
wiley +1 more source
Modulation of Aerobic Glycolysis Genes During the Progression of Retinitis Pigmentosa. [PDF]
Adani E +7 more
europepmc +1 more source
An eye on long‐duration spaceflight: Controversies, countermeasures and challenges
Abstract Space flight‐associated neuroocular syndrome (SANS) is a consequence of long‐duration space flight and is detected in two‐thirds of astronauts. In‐flight, this can cause a change in the refraction of the eyes, requiring graded hypermetropic ‘superfocus adjustable’ glasses, optic nerve head oedema and choroidal folds.
Vincent Wing Sum Ng +1 more
wiley +1 more source
The mechanisms, epidemiology, and clinical implications of thyroid hormones and age-related macular degeneration: a narrative review. [PDF]
Zhang X, Wang Z, Li Z, Zhan Z.
europepmc +1 more source
Mitochondrial control of ciliary gene expression and structure in striatal neurons
Abstract figure legend Neurons drive animal behaviour by receiving and transmitting information and require energy, primarily supplied by mitochondria, to function. Additionally, neurons need to sense environmental changes to adapt, a function that is locally played by the primary cilia.
Dogukan H. Ulgen +5 more
wiley +1 more source
Amacrine cell inputs to OFF midget ganglion cells in macaque retina
Abstract figure legend The goal of this study was to explain the findings from physiological studies that OFF midget ganglion cells had larger receptive field centers than expected from their dendritic field diameters. First, we confirmed that OFF mRGCs (OFF MGC) receive input from diffuse bipolar cells (DB) as well as OFF midget bipolar cells (FMB ...
David W. Marshak +8 more
wiley +1 more source
Illuminating retinoid flux in the neurosensory retina. [PDF]
Moshiri A, Sodhi A.
europepmc +1 more source
Hyperglycemic conditions increased mitochondrial membrane permeability and inflammatory signaling in Müller cells via cGAS‐STING activation. SYK was necessary for cGAS–STING activation and increased cytokine expression in Müller cells. Müller glia‐specific SYK deletion reduced glial activation and attenuated inflammatory cytokine expression in the ...
Esma I. Yerlikaya +8 more
wiley +1 more source
Lactate and histone H3K18 lactylation are associated with metabolic control of gene expression in the retina. [PDF]
Gaur M +12 more
europepmc +1 more source

