Results 221 to 230 of about 108,777 (309)

Laterally spreading AAV.SPR enables safe and efficient RS1 delivery to the macula after peripheral subretinal injection. [PDF]

Mol Ther
Andres-Mateos E, Kozlowski C, Zhang H, Fajardo D, Xu E, Enamorado IN, Calabro KR, Rayaprolu S, Havlik LP, Handy TE, Plummer CE, Stevenson V, Rind H, Leahy M, Boyd RF, Coleman KE, Boye SL, Boye SE.   +17 more
europepmc   +1 more source

A massively parallel reporter assay reveals context-dependent activity of homeodomain binding sites in vivo [PDF]

, 2018
Corbo, Joseph C, Hughes, Andrew E.O, Myers, Connie A   +2 more
core   +1 more source

Functional reassessment of extended splice region variants in MYO7A with hearing loss and Usher syndrome

The Journal of Pathology, Volume 269, Issue 2, Page 222-231, June 2026.
Abstract MYO7A is a causal gene, underlying Usher syndrome type 1B (USH1B) and both autosomal recessive (DFNB2) and dominant (DFNA11) non‐syndromic hearing loss. Despite the large number of reported MYO7A variants (over 2,200), variants located in an extended splice region remain difficult to interpret and are often classified as variants of uncertain ...
Tao Shi, Yu Huang, Xiaohuan Su, Lisheng Yu, Yixin Zhao, Jing Cheng   +5 more
wiley   +1 more source

Characterization of Usher Syndrome Type 2-Associated Proteins in the Retina via Affinity Purification-Mass Spectrometry. [PDF]

Mol Cell Proteomics
Zou J, Yu D, Mathur PD, Nordhagen CP, Zou X, Bonaldo P, Yang J.   +6 more
europepmc   +1 more source

GRKs and arrestins: Nomenclature and functions in GPCR‐dependent and ‐independent signalling

British Journal of Pharmacology, Volume 183, Issue 11, Page 2619-2633, June 2026.
G protein‐coupled receptor (GPCR) kinases (GRKs) and arrestins play a critical role in the regulation of GPCR signalling. Historic names of mammalian GRKs were replaced by systematic ones in the 1990s; however, both kinds of names are currently in use for mammalian arrestins.
Vsevolod V. Gurevich
wiley   +1 more source

Crosstalk Between R-Loops, RNA/DNA Modifications, and Cell Death Dynamics in Canine Models of Retinitis Pigmentosa. [PDF]

Invest Ophthalmol Vis Sci
Appelbaum T, Smith DA, Takahashi K, Sudharsan R, Beltran WA.   +4 more
europepmc   +1 more source

Heterokairic Genes and the Eco‐Evo‐Devo of Timing

Evolution &Development, Volume 28, Issue 2, June 2026.
Heterokairic genes as the bridge (Heterokairic Pathways?): Heterokairic genes are heterochronic regulators whose activity is modulated by environmental conditions. External cues (e.g., temperature, nutrition, oxygen, density: yellow box) are sensed (yellow arrows) and converted into endocrine and metabolic signals (purple box and arrow into fish's ...
Leandro Lofeu, Ehsan Pashay Ahi
wiley   +1 more source

Application of Machine Learning to Discriminate Photoreceptor Cell Species in Xenotransplanted Chimeric Retinas. [PDF]

Clin Transl Sci
Li KV, Pan A, Liu YV, Antonio-Aguirre B, Wang J, Adams M, McNerney C, Tun SBB, Jimenez K, Lu Y, Li Z, McNally M, Barathi VA, Johnston RJ, Singh MS.   +14 more
europepmc   +1 more source

Beyond red/far‐red sensing: phytochrome perception of the marine light field by microalgae

New Phytologist, Volume 250, Issue 5, Page 2837-2844, June 2026.
Summary Phytochromes (PHYs) are a major group of photoreceptors, described as red and far‐red light sensors in land plants. Recent genomic and metagenomic explorations have revealed the presence of PHYs also in various eukaryotic microalgae originating from distinct endosymbiotic events.
Carole Duchêne, Marianne Jaubert, Angela Falciatore   +2 more
wiley   +1 more source