Results 31 to 40 of about 54,838 (149)

High-Blue/Low-Red Mixed Light Modulates Photoperiodic Flowering in Chrysanthemum via Photoreceptor and Sugar Pathways

Plants
Chrysanthemum (Chrysanthemum morifolium Ramat.), a typical short-day plant (SDP), relies on photoperiod and light quality signals to regulate flowering and growth.
Jingli Yang, Zhengyang Cheng, Jinnan Song, Byoung Ryong Jeong   +3 more
doaj   +1 more source

Age-dependent changes of monocarboxylate transporter 8 availability in the postnatal murine retina

Frontiers in Cellular Neuroscience, 2016
The thyroid hormones (TH) triiodothyronine (T3) and its prohormone thyroxine (T4) are crucial for retinal development and function, and increasing evidence points at TH dysregulation as a cause for retinal degenerative diseases.
Yoshiyuki Henning, Karol Szafranski
doaj   +1 more source

Local Insulin for Local Needs? Insights into Retinal Insulin Signaling and RPE Metabolism

Biomolecules
Insulin is a key anabolic hormone traditionally considered to be exclusively produced by pancreatic β-cells. Insulin exerts several systemic effects involved in glucose uptake and metabolism.
Matilde Balbi, Alessandra Puddu, Andrea Amaroli, Davide Maggi, Isabella Panfoli, Silvia Ravera   +5 more
doaj   +1 more source

The Na+/Ca2+, K+ exchanger NCKX4 is required for efficient cone-mediated vision

eLife, 2017
Calcium (Ca2+) plays an important role in the function and health of neurons. In vertebrate cone photoreceptors, Ca2+ controls photoresponse sensitivity, kinetics, and light adaptation.
Frans Vinberg, Tian Wang, Alicia De Maria, Haiqing Zhao, Steven Bassnett, Jeannie Chen, Vladimir J Kefalov   +6 more
doaj   +1 more source

Two Decades of Optogenetic Tools: A Retrospective and a Look Ahead

Advanced Genetics
Over the past two decades, optogenetics has evolved from a conceptual framework into a powerful and versatile technology for controlling cellular processes with light.
Xiao Duan, Mo Zhu, Shiqiang Gao
doaj   +1 more source

HK2 Mediated Glycolytic Metabolism in Mouse Photoreceptors Is Not Required to Cause Late Stage Age-Related Macular Degeneration-Like Pathologies

Biomolecules, 2021
Age-related macular degeneration (AMD) is a multifactorial disease of unclear etiology. We previously proposed that metabolic adaptations in photoreceptors (PRs) play a role in disease progression.
Shun-Yun Cheng, Anneliese Malachi, Joris Cipi, Shan Ma, Richard S. Brush, Martin-Paul Agbaga, Claudio Punzo   +6 more
doaj   +1 more source

AAV-CRISPR/Cas9 Gene Editing Preserves Long-Term Vision in the P23H Rat Model of Autosomal Dominant Retinitis Pigmentosa

Pharmaceutics, 2022
Retinitis pigmentosa (RP) consists of a group of inherited, retinal degenerative disorders and is characterized by progressive loss of rod photoreceptors and eventual degeneration of cones in advanced stages, resulting in vision loss or blindness.
Saba Shahin, Hui Xu, Bin Lu, Augustus Mercado, Melissa K. Jones, Benjamin Bakondi, Shaomei Wang   +6 more
doaj   +1 more source

Acetylcholine Depolarizes Barnacle Photoreceptors [PDF]

Journal of Experimental Biology, 1985
ABSTRACT A variety of vertebrate and invertebrate sensory cells are known to be sensitive to acetylcholine (ACh), although the purpose of ACh receptors on these cells is not understood. Acetylcholine elicits action potentials from the sensory cell of the crayfish stretch receptor organ, which receives inhibitory but not excitatory ...
L C, Timpe, A E, Stuart
openaire   +2 more sources

Aberrant hiPSCs-Derived from Human Keratinocytes Differentiates into 3D Retinal Organoids that Acquire Mature Photoreceptors

Cells, 2019
Human induced pluripotent stem cell (hiPSC)-derived three-dimensional retinal organoids are a new platform for studying the organoidogenesis. However, recurrent genomic aberration, acquired during generation of hiPSCs, limit its biomedical application ...
Rupendra Shrestha, Yao-Tseng Wen, Dah-Ching Ding, Rong-Kung Tsai   +3 more
doaj   +1 more source

The Relevance of Oxidative Stress in the Pathogenesis and Therapy of Retinal Dystrophies

Antioxidants, 2020
Retinal cell survival requires an equilibrium between oxygen, reactive oxygen species, and antioxidant molecules that counteract oxidative stress damage.
Elena B. Domènech, Gemma Marfany
doaj   +1 more source