Results 61 to 70 of about 2,816 (163)

Structural and functional mechanisms of actin isoforms

The FEBS Journal, Volume 292, Issue 3, Page 468-482, February 2025.
Actin isoforms are abundant cytoskeletal proteins that exhibit high structural and functional conservation yet have different cellular roles. This review discusses the structural and functional roles of actin isoforms, their biochemistries, and interactions with myosin motor proteins.
Sarah M. Heissler, Krishna Chinthalapudi
wiley   +1 more source

Non‐Invasive, Bioluminescence‐Based Visualisation and Quantification of Bacterial Infections in Arabidopsis Over Time

Molecular Plant Pathology, Volume 26, Issue 2, February 2025.
Development of a non‐invasive high‐throughput phenotyping pipeline to visualise and quantify progression of bioluminescent bacterial pathogens in Arabidopsis rosettes over time. ABSTRACT Plant‐pathogenic bacteria colonise their hosts using various strategies, exploiting both natural openings and wounds in leaves and roots.
Nanne W. Taks, Mathijs D. Batstra, Ronald F. Kortekaas, Floris D. Stevens, Sebastian Pfeilmeier, Harrold A. van den Burg   +5 more
wiley   +1 more source

Genome mining unearths a hybrid nonribosomal peptide synthetase-like-pteridine synthase biosynthetic gene cluster

eLife, 2017
Nonribosomal peptides represent a large class of metabolites with pharmaceutical relevance. Pteridines, such as pterins, folates, and flavins, are heterocyclic metabolites that often serve as redox-active cofactors.
Hyun Bong Park, Corey E Perez, Karl W Barber, Jesse Rinehart, Jason M Crawford   +4 more
doaj   +1 more source

Natural pigments derived from plants and microorganisms: classification, biosynthesis, and applications

Plant Biotechnology Journal, Volume 23, Issue 2, Page 592-614, February 2025.
Summary Pigments, as coloured secondary metabolites, endow the world with a rich palette of colours. They primarily originate from plants and microorganisms and play crucial roles in their survival and adaptation processes. In this article, we categorize pigments based on their chemical structure into flavonoids, carotenoids, pyrroles, quinones ...
Qian Tang, Zhibo Li, Ningxin Chen, Xiaozhou Luo, Qiao Zhao   +4 more
wiley   +1 more source

Biosensor‐Guided Engineering of a Baeyer‐Villiger Monooxygenase for Aliphatic Ester Production

ChemBioChem, Volume 26, Issue 1, January 2, 2025.
In this work, aliphatic esters are produced by Baeyer‐Villiger monooxygenases (BVMOs) from ketone substrates. Through an artificial enzyme cascade, esters are converted into aldehydes, which are detected by a bacterial luciferase. This set‐up presents the first genetically encoded biosensor system monitoring BVMO activity and greatly accelerated the ...
Thaleia Sakoleva, Florian Vesenmaier, Lena Koch, Jarne E. Schunke, Kay D. Novak, Sascha Grobe, Mark Dörr, Uwe T. Bornscheuer, Thomas Bayer   +8 more
wiley   +1 more source

Preliminary Screening on Antibacterial Crude Secondary Metabolites Extracted from Bacterial Symbionts and Identification of Functional Bioactive Compounds by FTIR, HPLC and Gas Chromatography–Mass Spectrometry

Molecules
Secondary metabolites, bioactive compounds produced by living organisms, can unveil symbiotic relationships in nature. In this study, soilborne entomopathogenic nematodes associated with symbiotic bacteria (Xenorhabdus stockiae and Photorhabdus ...
Gobinath Chandrakasan, Juan Fernando García-Trejo, Ana Angelica Feregrino-Pérez, Humberto Aguirre-Becerra, Enrique Rico García, María Isabel Nieto-Ramírez   +5 more
doaj   +1 more source

Temperature Restriction in Entomopathogenic Bacteria

Frontiers in Microbiology, 2020
Temperature plays an important role in bacteria-host interactions and can be a determining factor for host switching. In this study we sought to investigate the reasons behind growth temperature restriction in the entomopathogenic enterobacterium ...
Alexia Hapeshi, Joseph R. J. Healey, Geraldine Mulley, Nicholas R. Waterfield   +3 more
doaj   +1 more source

High-throughput sequencing analysis reveals genomic similarity in phenotypic heterogeneous Photorhabdus luminescens cell populations

Annals of Microbiology, 2022
Purpose Phenotypic heterogeneity occurs in many bacterial populations: single cells of the same species display different phenotypes, despite being genetically identical.
Nazzareno Dominelli, Heidi Yoko Jäger, Angela Langer, Andreas Brachmann, Ralf Heermann   +4 more
doaj   +1 more source

High‐yield, plant‐based production of an antimicrobial peptide with potent activity in a mouse model

Plant Biotechnology Journal, Volume 22, Issue 12, Page 3392-3405, December 2024.
Summary Plants offer a promising chassis for the large‐scale, cost‐effective production of diverse therapeutics, including antimicrobial peptides (AMPs). However, key advances will reduce production costs, including simplifying the downstream processing and purification steps.
Shahid Chaudhary, Zahir Ali, Aarón Pantoja‐Angles, Sherin Abdelrahman, Cynthia Olivia Baldelamar Juárez, Gundra Sivakrishna Rao, Pei‐Ying Hong, Charlotte Hauser, Magdy Mahfouz   +8 more
wiley   +1 more source

Environmental drivers of trait changes in Photorhabdus luminescens

Biological Control, 2016
Abstract Biological control agents have become increasingly important in integrated pest management programs. However, certain traits of these agents that are needed for efficient biocontrol often decrease or are lost during in vitro rearing. Entomopathogenic nematodes (EPNs) often exhibit trait deterioration when reared under laboratory conditions ...
Dana Blackburn, Burke Crawford, David I. Shapiro-Ilan, Byron J. Adams   +3 more
openaire   +1 more source