Results 101 to 110 of about 4,387 (184)

Distinct Nanohoop Structures and Ratiometric Emissions of Isomeric DPAC‐Based Macrocycles Tuned by Nano‐Twisting of Stiff‐Stilbene Optical‐Switches

Small, EarlyView.
Tunable nano‐twisted structures of novel isomeric macrocycles, which were controlled by cis/trans isomerizations of stiff‐stilbene units under light irradiations, have been exploited to modulate bent and planar configurations of 9,14‐diphenyl‐9,14‐dihydrodibenzo[a,c]phenazine (DPAC) moieties and adjust their ratiometric emissions. External factors, i.e.
Nguyen Thanh Trung, Shao‐Chen Lu, Po‐Jung Tseng, Tu Thi Kim Cuc, Chun‐Wei Huang, Jeng‐Kuei Chang, Said Jalife, Judy I. Wu, Simona Steponkiene, Vitalijus Karabanovas, Tung‐Kung Wu, Hong‐Cheu Lin   +11 more
wiley   +1 more source

Optical Control of Therapeutic Synthetic Cells: Controlling Biomolecule Synthesis, Activation, and Communication

Small Methods, EarlyView.
Combining synthetic cells engineering, cell‐free expression, and optical regulation may enable a new generation of programmable synthetic cell platforms. By providing spatiotemporal control over biomolecule synthesis, activation, transport, release, and communication, light offers a versatile strategy for coordinating proteins, RNAs, peptides, and ...
Gia Bao Leon Hoang, Taniya Chakraborty
wiley   +1 more source

Ten‐Membered Cyclic Azobenzene: Electrochemical Synthesis and Photochromic Properties

ChemElectroChem
Cyclic azobenzenes generally exhibit enhanced photophysical properties compared to conventional linear azobenzenes, such as visible‐light activation and exceptional thermal stability.
Qianqian Niu, Dan Li, Lijiao Guo, Xinyuan Sun, Yan Liu, Longjiu Cheng, Baokang Jin   +6 more
doaj   +1 more source

Crystal structure of the bifunctional enzyme phosphoribosyl isomerase A from Mycobacterium tuberculosis with bound light‐controllable inhibitor

Acta Crystallographica Section F, Volume 82, Issue 11, Page 385-390, November 2026.
We have determined the crystal structure of an isomerase catalyzing two steps in histidine and tryptophan biosynthesis with a bound light‐switchable competitive inhibitor. The work explains the mode of action of the inhibitor and describes the discovery of a hitherto unknown third phosphate‐binding site of the enzyme.The enzyme phosphoribosyl isomerase
Chitra Rajendran, Reinhard Sterner
wiley   +1 more source

Solvent‐Dependent Modulation of Thermal Half‐Lives in Azothiadiazole Photoswitches

Azothiadiazole‐based photoswitches are a promising class of azoheteroarenes with potential applications in photopharmacology. Thiadiazoles are five‐membered heterocycles containing one sulfur and two nitrogen atoms, existing in four ...
P. K. Hashim, Kaveri Prasad, Masaki Horie, Pavel Sidorov, Wataru Setaka, Nusaiba Madappuram Cheruthu, Ajmal Koya Pulikkal, Sen Regi Abraham   +7 more
core   +1 more source

Light‐Enhanced Chloride Transport by Thiourea‐Appended Molecular Motor

Angewandte Chemie, Volume 138, Issue 41, 5 October 2026.
A molecular motor functionalized with a thiourea anion‐binding motif mediates transmembrane chloride transport. Light irradiation enhances transport efficiency by populating a more active metastable isomer, which slowly equilibrates to the initial stable isomer.
Abhishek Mondal, Sander J. Wezenberg
wiley   +2 more sources

Split‐Aperture Xolography – Linear Volumetric Photoactivation with Short Axial Dimension and Low out of Focus Excitation

Advanced Science
Spatially confined photo‐excitation with the lowest possible activation of the remaining volume is of central importance for high‐resolution high‐density optical data storage, fluorescence microscopy, 3D‐lithography, and 3D‐printing.
Martin Regehly, Stefan Hecht
doaj   +1 more source

Rapid Access to Photoswitchable RNA Binders: Fluorination Enhances Protein Rescue by Exon Inclusion

Chemistry – A European Journal, Volume 32, Issue 39, 22 October 2026.
An adaptable approach, many light‐switchable RNA binders. We report a versatile strategy for rapidly synthesizing photoswitchable RNA binders. The ligands can target SMN2 pre‐mRNA, restoring the levels of the corresponding protein by exon‐inclusion rescue.
Lei Zhang, Nemanja Djokovic, Alexander Herr, Anna Wacker, Emily Swanson Hay, Daniel Santana, Amanda E. Hargrove, Harald Schwalbe, Katarina Nikolic, Frank Abendroth, Olalla Vázquez   +10 more
wiley   +1 more source

All-visible-light-driven stiff-stilbene photoswitches [PDF]

Molecular photoswitches are potent tools to construct dynamic functional systems and responsive materials that can be controlled in a non-invasive manner. As P-type photoswitches, stiff-stilbenes attract increasing interest, owing to their superiority in
Feringa, B.L., Danowski, Wojciech, Sheng, Jinyu, Stindt, Charlotte N.; id_orcid, Buma, W.J., Xu, Fan, Crespi, Stefano, Feringa, Ben L., Stindt, Charlotte N., Crespi, Stefano; id_orcid, Hilbers, M.F., Sheng, J., Stindt, C.N., Crespi, S., Xu, F., Buma, Wybren Jan, Danowski, W., Hilbers, Michiel F., Buma, Wybren Jan,, Sheng, J.Q., Hilbers, Michiel F.,, Sheng, Jinyu,, Danowski, Wojciech,, Stindt, Charlotte N.,, Feringa, Ben L.,, Xu, Fan,, Crespi, Stefano,   +26 more
core   +1 more source

Hybrid Macrocyclic Peptides — Synthetic Strategies to Diversify and Cyclize Peptide Libraries in Phage Display Selections

Chemistry – A European Journal, Volume 32, Issue 39, 22 October 2026.
Hybrid macrocyclic peptides unite genetically encoded peptide libraries with the structural complexity of synthetic small molecules. This Review critically analyzes phage‐compatible cyclization and diversification chemistries, highlights emerging opportunities beyond traditional cysteine‐based approaches, and outlines how future advances may enable the
Titia Rixt Oppewal, Clemens Mayer
wiley   +1 more source