Results 111 to 120 of about 4,387 (184)

Multi‐state Photoswitching in Thienoquinoid‐Based Fluorescent Trithiophenes

Chemistry – A European Journal, Volume 32, Issue 39, 22 October 2026.
A methine‐bridged trithiophene with a thienoquinoid core undergoes photoisomerization of both C═C bonds, affording three geometrical isomers in a ratio controlled by the irradiation wavelength. Despite full π‐conjugation, the system retains fluorescence, enabling wavelength‐addressable multi‐state switching with luminescent readout.
Rio Nishimura, Stefan Hecht, Shohei Saito, Ken‐ichi Yamashita   +3 more
wiley   +1 more source

Chelation‐Assisted Metal‐Catalyzed Ligation and Cleavage Reactions for Chemical Biology

European Journal of Organic Chemistry, Volume 29, Issue 39, 22 October 2026.
Chelation‐assisted transition metal catalysis has emerged as a promising complement to bioorthogonal click chemistry for studying biological processes. By pre‐organizing catalytic metal centers, designed coordinating substrates enhance reactivity and biocompatibility, enabling site‐selective ligation and decaging reactions in complex biological media ...
Emilie Plantiveau, Maxime Riberaud, Frédéric Taran, Antoine Sallustrau   +3 more
wiley   +1 more source

Bistable Switching of π‐Conjugation in a Dithienylethene‐Bridged Luminescent Trityl Diradicaloid

Angewandte Chemie International Edition, Volume 65, Issue 43, 19 October 2026.
Photoswitches that affect π‐conjugation offer a powerful strategy for external manipulation of luminescent diradicals. Dithienylethene‐linked persistent trityl diradicaloids, DTE‐TTM2 and F6‐DTE‐TTM2, exhibit bistable switching of their optical, electrochemical and magnetic properties.
Xingmao Chang, Sören Schlittenhardt, Julia Zolg, Maximilian Herm, Siyang He, Vivek Chandrakant Wakchaure, Dinar Abdullin, Robert Göstl, Dirk M. Guldi, Alexander J. C. Kuehne, Sabine Richert, Max von Delius   +11 more
wiley   +1 more source

Control of Gemcitabine Activity With Blue and Red Light

Chemistry – A European Journal, Volume 32, Issue 38, 13 October 2026.
Treating cancer with chemotherapy is generally associated with many side effects, which can be addressed by selectively releasing the desired drugs with visible light. Sixteen new blue light‐activatable cytostatics were introduced, with the gemcitabine derivative exhibiting ideal properties.
Nils F. Kersten, Konstantin L. Stock, Marius Hyprath, Hannah Weisser, Timo Weinrich, Dieter Steinhilber, Alexander Heckel   +6 more
wiley   +1 more source

In Silico to In Cerebro—Development of the Orexin Receptor Antagonist “Photorexant” for Photomodulation In Vitro and in Mouse Brains

Angewandte Chemie International Edition, Volume 65, Issue 42, 12 October 2026.
Following a structure‐based design approach, photoswitchable derivatives of the FDA‐approved drug suvorexant were designed, docked, synthesized, and characterized pharmacologically at the orexin 1 and 2 receptors (OX1R and OX2R). Optimized “photorexant” showed up to an 11‐fold difference in IC50 between photoisomers, enabled dynamic and reversible ...
Marcus Angermann, Marie H. Deventer, Vicente Ledesma‐Martin, Nuno Martinho, Alix Flake, Silvia Mori, Angel Nuñez, Jaime Pignatelli, Rita C. Guedes, Christophe P. Stove, Michael Decker   +10 more
wiley   +1 more source

Multimode Photoswitches Incorporating Dihydroazulene

The dihydroazulene/vinylheptafulvene (DHA/VHF) system is a photo-/thermo-switch couple that has found interest for MOST applications. Structure–property relationships have been established for tuning optical and isomerization properties of this pair as ...
Nielsen, Mogens Brøndsted, Cacciarini, Martina   +1 more
core   +1 more source

Expanding the toolbox of photoswitches for DNA nanotechnology using Arylazopyrazoles

, 2018
Photoregulation is among the most promising tools for development of dynamic DNA nanosystems, due to its high spatiotemporal precision, biocompatibility, and ease of use.
Hannam, J., Volker Adam, Michael Famulok, Jeffrey S. Hannam, Adam, V., Marko Škugor, Julián Valero, Prusty, D., Kloeckner, B., Bernhard Klöckner, Famulok, M., Skugor, M., Mathias Centola, Deepak K. Prusty, Valero, J., Centola, M.   +15 more
core   +1 more source

Exploiting negative photochromism to harness a four-photon-like fluorescence response with two-photon excitation

Nature Communications
Combining nonlinear optical processes and photoswitching transcends the limitations of conventional and even standalone super-resolution imaging. While photoswitching enables resolution improvement, it is typically constrained by limited imaging depth ...
Carlos Benitez-Martin, Jean Rouillon, Eduard Fron, Flip de Jong, Morten Grøtli, Johan Hofkens, Uwe Pischel, Joakim Andréasson   +7 more
doaj   +1 more source

Development and characterization of amino donor-acceptor Stenhouse adducts

Nature Communications
Donor-acceptor Stenhouse adducts (DASAs) are molecular photoswitches spurring wide interest because of their dynamic photophysical properties, complex photoswitching mechanism, and diverse applications.
Cesar A. Reyes, Hye Joon Lee, Connie Karanovic, Elias Picazo   +3 more
doaj   +1 more source

'Click'-able hemiindigo triazole photoswitches with switchable fluorescence

Herein we report the synthesis and photocharacterisation of a library of triazole hemiindigos as new, easily functionalised indigoid photoswitches featuring switchable fluorescence.
Maria Storm-Thomsen, Robert C O'toole, George Williams, Alex Wilmshurst, Stefano Crespi, Zhihao Ling, Alex Buchanan, Rebecca Kerridge, Roman Y Peshkov, Richard Knighton, Williams, George T., O’Toole, Robert C.P., Crespi, Stefano, Wilmshurst, Alexander M., Knighton, Richard C., Thomsen, Maria Storm, Peshkov, Roman Yu, Buchanan, Alex, Kerridge, Rebecca, Ling, Zhihao   +19 more
core   +1 more source