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Graphene as Photothermal Therapeutic Agents
2022Light-assisted hyperthermic therapy is a promising strategy to treat cancer. Graphene and their derivatives with unique physiochemical properties, intrinsic near infrared absorption, and ability to transduce the absorbed light energy into heat, have attracted researchers to use them for photothermal therapy (PTT).
Vishnu, Revuri +2 more
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Organelle-targeted photothermal agents for cancer therapy
Chemical Communications, 2021This feature article summarizes the recent advances in organelle-targeted PTT agents over the past ten years.
Eunbin Hwang, Hyo Sung Jung
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Bioorganic Chemistry, 2021
Organic small molecules with near-infrared (NIR) absorption hold great promise as the phototheranostic agents for clinical translation by virtue of their inherent merits such as well-defined chemical structure, high purity and good reproducibility. Probes that happen to be based on cyanine dyes exhibit strong NIR-absorbing and efficient photothermal ...
Wangqing, Bian +11 more
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Organic small molecules with near-infrared (NIR) absorption hold great promise as the phototheranostic agents for clinical translation by virtue of their inherent merits such as well-defined chemical structure, high purity and good reproducibility. Probes that happen to be based on cyanine dyes exhibit strong NIR-absorbing and efficient photothermal ...
Wangqing, Bian +11 more
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Fe-involved nanostructures act as photothermal transduction agents in cancer photothermal therapy
Colloids and Surfaces B: Biointerfaces, 2023Cancer, a disease notorious for its difficult therapy regimen, has long puzzled researchers. Despite attempts to cure cancer using surgery, chemotherapy, radiotherapy, and immunotherapy, their effectiveness is limited. Recently, photothermal therapy (PTT), a rising strategy, has gained attention.
Zewei, Jiang +6 more
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A Dual‐Targeted Organic Photothermal Agent for Enhanced Photothermal Therapy
Angewandte Chemie International Edition, 2018AbstractThe development of highly effective anticancer drugs that cause minimal damage to the surrounding normal tissues is a challenging topic in cancer therapy. Herein, we demonstrate a dual‐targeted organic molecule that functions as a photothermal agent by actively targeting tumor tissue and mitochondria to selectively kill cancer cells.
Hongyu Wang +5 more
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Tunable Nanostructures as Photothermal Theranostic Agents
Annals of Biomedical Engineering, 2011The theranostic potential of several nanostructures has been discussed in the context of photothermal therapies and imaging. In the last several decades, the burden of cancer has grown rapidly, making the need for new theranostic approaches vital. Lasers have emerged as promising tools in cancer treatment, especially with the advent of photothermal ...
Joseph K, Young +2 more
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Angewandte Chemie, 2021
AbstractSmall organic photothermal agents (SOPTAs) that absorb in the second near‐infrared (NIR‐II, 1000–1700 nm) window are highly desirable in photothermal therapy for their good biocompatibility and deeper tissue penetration. However, the design of NIR‐II absorbing SOPTAs remains a great challenge. Herein, we report that molecular engineering of BF2
Zhiyong Jiang +6 more
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AbstractSmall organic photothermal agents (SOPTAs) that absorb in the second near‐infrared (NIR‐II, 1000–1700 nm) window are highly desirable in photothermal therapy for their good biocompatibility and deeper tissue penetration. However, the design of NIR‐II absorbing SOPTAs remains a great challenge. Herein, we report that molecular engineering of BF2
Zhiyong Jiang +6 more
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Chemical Communications, 2023
A heat shock protein-inhibiting organic molecule with endoplasmic reticulum targeting was synthesized for mild-temperature photothermal therapy, which can enhance the efficacy of photothermal therapy and suppress the growth of tumors in mice.
Xinhao Zhang +6 more
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A heat shock protein-inhibiting organic molecule with endoplasmic reticulum targeting was synthesized for mild-temperature photothermal therapy, which can enhance the efficacy of photothermal therapy and suppress the growth of tumors in mice.
Xinhao Zhang +6 more
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ACS Applied Materials & Interfaces, 2018 Theranostic nanomedicines involved in photothermal therapy (PTT) have received constant attention as promising alternatives to traditional therapies in clinic.
Kaiwen Chang, Yubin Liu, Dongliang Li
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A Protein‐Binding Molecular Photothermal Agent for Tumor Ablation
Angewandte Chemie International Edition, 2021AbstractPhotothermal therapy usually requires a high power density to activate photothermal agent for effective treatment, which inevitably leads to damage to normal tissues and inflammation in tumor tissues. Herein, we rationally design a protein‐binding strategy to build a molecular photothermal agent for photothermal ablation of tumor.
Mingwan Shi +7 more
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