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A Dual‐Targeted Organic Photothermal Agent for Enhanced Photothermal Therapy
Angewandte Chemie International Edition, 2018AbstractThe development of highly effective anticancer drugs that cause minimal damage to the surrounding normal tissues is a challenging topic in cancer therapy. Herein, we demonstrate a dual‐targeted organic molecule that functions as a photothermal agent by actively targeting tumor tissue and mitochondria to selectively kill cancer cells.
Hongyu Wang +5 more
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Tunable Nanostructures as Photothermal Theranostic Agents
Annals of Biomedical Engineering, 2011The theranostic potential of several nanostructures has been discussed in the context of photothermal therapies and imaging. In the last several decades, the burden of cancer has grown rapidly, making the need for new theranostic approaches vital. Lasers have emerged as promising tools in cancer treatment, especially with the advent of photothermal ...
Joseph K, Young +2 more
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Angewandte Chemie, 2021
AbstractSmall organic photothermal agents (SOPTAs) that absorb in the second near‐infrared (NIR‐II, 1000–1700 nm) window are highly desirable in photothermal therapy for their good biocompatibility and deeper tissue penetration. However, the design of NIR‐II absorbing SOPTAs remains a great challenge. Herein, we report that molecular engineering of BF2
Zhiyong Jiang +6 more
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AbstractSmall organic photothermal agents (SOPTAs) that absorb in the second near‐infrared (NIR‐II, 1000–1700 nm) window are highly desirable in photothermal therapy for their good biocompatibility and deeper tissue penetration. However, the design of NIR‐II absorbing SOPTAs remains a great challenge. Herein, we report that molecular engineering of BF2
Zhiyong Jiang +6 more
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Non-plasmonic NIR-Activated Photothermal Agents for Photothermal Therapy
2020Photothermal therapies rely on various types of optically active nanomaterials, such as carbon, silicon, titanium dioxide, iron-based, polymeric, and rare earth-doped nanomaterials, which are aiming to convert light into heat. However, lack of clear guidelines and standardized approaches to determine their photothermal properties hinders quantitative ...
L. Marciniak +3 more
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Chemical Communications, 2023
A heat shock protein-inhibiting organic molecule with endoplasmic reticulum targeting was synthesized for mild-temperature photothermal therapy, which can enhance the efficacy of photothermal therapy and suppress the growth of tumors in mice.
Xinhao Zhang +6 more
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A heat shock protein-inhibiting organic molecule with endoplasmic reticulum targeting was synthesized for mild-temperature photothermal therapy, which can enhance the efficacy of photothermal therapy and suppress the growth of tumors in mice.
Xinhao Zhang +6 more
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Nanoscale, 2014
Copper sulphides, as a novel kind of photothermal agent for photothermal therapy (PTT) of cancer cells, have attracted increasing attention in recent years due to good photostability, synthetic simplicity, low toxicity and low cost. However, the unsatisfactory photothermal conversion efficiency of copper sulphides limits their bioapplication as PTT ...
Bo, Li +6 more
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Copper sulphides, as a novel kind of photothermal agent for photothermal therapy (PTT) of cancer cells, have attracted increasing attention in recent years due to good photostability, synthetic simplicity, low toxicity and low cost. However, the unsatisfactory photothermal conversion efficiency of copper sulphides limits their bioapplication as PTT ...
Bo, Li +6 more
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A Protein‐Binding Molecular Photothermal Agent for Tumor Ablation
Angewandte Chemie International Edition, 2021AbstractPhotothermal therapy usually requires a high power density to activate photothermal agent for effective treatment, which inevitably leads to damage to normal tissues and inflammation in tumor tissues. Herein, we rationally design a protein‐binding strategy to build a molecular photothermal agent for photothermal ablation of tumor.
Mingwan Shi +7 more
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Stimuli-activated molecular photothermal agents for cancer therapy
Chemical Communications, 2021Recent progress in the study of stimuli-activated molecular photothermal agents is summarized from different stimuli, including pH, bioactive small molecules, and enzymes.
Kaiye Wang +5 more
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Nanomaterials as multimodal photothermal agents (PTAs) against ‘Superbugs’
Journal of Materials Chemistry B, 2023This study demonstrates the recent advancements of multimodal photothermal applications in order to ablate superbugs by using functional nanomaterials.
Shubham Roy, Jhilik Roy, Bing Guo
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Self‐Regenerating Photothermal Agents for Tandem Photothermal and Thermodynamic Tumor Therapy
Small MethodsAbstractSmall molecule‐based photothermal agents (PTAs) hold promising future for photothermal therapy; however, unexpected inactivation exerts negative impacts on their application clinically. Herein, a self‐regenerating PTA strategy is proposed by integrating 2,2′‐azino‐bis(3‐ethylbenzothiazoline‐6‐sulfonic acid) radical cation (ABTS•+) with a ...
Xiangli Li +8 more
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