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Single walled carbon nanohorns as photothermal cancer agents

Lasers in Surgery and Medicine, 2011
AbstractBackgroundNanoparticles have significant potential as selective photo‐absorbing agents for laser based cancer treatment. This study investigates the use of single walled carbon nanohorns (SWNHs) as thermal enhancers when excited by near infrared (NIR) light for tumor cell destruction.MethodsAbsorption spectra of SWNHs in deionized water at ...
Jon R, Whitney   +13 more
openaire   +2 more sources

A Golgi Apparatus‐Targeted Photothermal Agent with Protein Anchoring for Enhanced Cancer Photothermal Therapy

Advanced Healthcare Materials
AbstractThe Golgi apparatus (GA) is central in shuttling proteins from the endoplasmic reticulum to different cellular areas. Therefore, targeting the GA to precisely destroy its proteins through local heat could induce apoptosis, offering a potential avenue for effective cancer therapy.
Mingwan Shi   +6 more
openaire   +2 more sources

A Ferrocene-Based Supramolecular Photothermal Agent for Enhanced Photothermal/Ferroptosis Therapy and Immune Activation

Biomacromolecules
Photothermal therapy (PTT) is impeded by limited light penetration depth and cellular heat resistance induced by overexpressed heat shock proteins. Herein, we propose a ferrocene (Fc)-based supramolecular photothermal agent (PTA) to improve the therapeutic efficacy.
Jing Qian   +5 more
openaire   +2 more sources

Dissolving Microneedle Patches Integrating Optical Clearing and Photothermal Agents for Improved Photothermal Disinfection

Macromolecular Bioscience
AbstractPhotothermal disinfection is an emerging and efficient therapeutic method for treating various infections. However, the therapeutic efficacy is hindered by the poor tissue penetration of light. While tissue optical clearance technology can enhance light transmission, the stratum corneum impedes the delivery of clearing agents to deeper tissues.
Yiyan Cheng   +4 more
openaire   +2 more sources

A BRD4‐Targeting Photothermal Agent for Controlled Protein Degradation

Angewandte Chemie International Edition
AbstractBRD4 protein plays a pivotal role in cell cycle regulation and differentiation. Disrupting the activity of BRD4 has emerged as a promising strategy for inhibiting the growth and proliferation of cancer cells. Herein, we introduced a BRD4‐targeting photothermal agent for controlled protein degradation, aiming to enhance low‐temperature ...
Mingwan Shi   +7 more
openaire   +2 more sources

Nanozymes as Photothermal-Catalytic Agents

2021
Xianwen Wang   +3 more
openaire   +1 more source

Silk fibroin-photothermal agent composites: Innovations in biomedicine

International Journal of Biological Macromolecules
Silk fibroin (SF), as a naturally occurring polymer, has emerged as a highly appealing biomaterial within the field of biomedicine, attributed to its hierarchical architecture, exceptional mechanical characteristics, and adjustable biodegradability. Photothermal agents (PTAs) are distinguished by their high photothermal conversion efficiency, favorable
Luyao, Zhong   +6 more
openaire   +2 more sources

Photothermal agents based on small organic fluorophores with intramolecular motion

Acta Biomaterialia, 2022
Fangyuan Lv   +2 more
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