Results 91 to 100 of about 32,210 (274)

An integrin-targeted photoactivatable Pt(IV) complex as a selective anticancer pro-drug: synthesis and photoactivation studies [PDF]

open access: yes, 2015
A new anticancer agent based on the conjugation of a photoactivatable Pt(IV) pro-drug to a cyclic RGD-containing peptide is described. Upon visible light irradiation, phototoxicity was induced preferentially in SK-MEL-28 melanoma cancer cells ...
Artigas Solé, Gerard   +7 more
core   +2 more sources

Boron Difluoride Formazanate Dye With Donor Planarization Engineering for 1060 nm Laser Activated Photothermal Theranostics

open access: yesAdvanced Science, EarlyView.
The donor engineering strategy enhances the planarity of the π‐conjugated molecular framework, thereby promoting stronger intramolecular charge transfer (ICT). This structural refinement in FBDFDPA leads to a pronounced bathochromic shift in absorption from the NIR‐I to the NIR‐II region, enabling effective photothermal therapy (PTT) for tumors within ...
Kang Xu   +8 more
wiley   +1 more source

A Genetically Encoded Homocysteine Precursor to Probe Protein Active Sites and to Addict Escherichia coli to a Noncanonical Amino Acid Directly Involved in Catalysis

open access: yesAngewandte Chemie, EarlyView.
A new genetically encoded amino acid is chemically converted into homocysteine (Hcy) under mild conditions to probe and to activate protein active sites. Surprisingly, Hcy can replace cysteine or serine residues in several enzymes. Its potential for a widespread use in proteins is further underlined by rendering Escherichia coli dependent on Hcy ...
Clara Dunker, Henning D. Mootz
wiley   +2 more sources

Modulation of COX2 and hTERT expression by Photodynamic Therapy in human colon cancer cells [PDF]

open access: yes, 2009
Photodynamic therapy (PDT) was employed as a cancer therapy with photosensitizer (PS)-loaded cancer cells, eradicated by the reactive oxygen species after light activation.
Chu, ESM, Yow, CLMN
core   +1 more source

Bioprinted Organoids: An Innovative Engine in Biomedicine

open access: yesAdvanced Science, EarlyView.
Bioprinted organoids refer to either the printing of stem cells into tissue shape and subsequent differentiate into organoids, or assembling induced organoids as bioinks to replicate native organ. It enables the creation of miniaturized organs with complex architectures and physiological functions, potentially enhancing reproducibility, throughput, and
Zhengwei Li   +11 more
wiley   +1 more source

Photobleaching and phototoxicity of mitochondria in live cell fluorescent super-resolution microscopy

open access: yesMitochondrial Communications
Photobleaching and phototoxicity can induce detrimental effects on cell viability and compromise the integrity of collected data, particularly in studies utilizing super-resolution microscopes.
Chia-Hung Lee   +2 more
doaj  

Findings of the DRAFT 2004 Texas Water Quality Inventory and 303(d) List for the Austin Area [PDF]

open access: yes, 2004
This 2004 summary of findings highlights the most common water quality impairments found in Waller Creek.The Texas Water Quality Inventory (305(b) report) is prepared by the Texas Commission on Environmental Quality (TCEQ) and submitted to the U.S ...
Gosselink, Leila
core   +1 more source

Heme/NADH Mimics Co‐Decorated Allosteric Capsules for Regulating Oxygen Activation and Upregulating Intracellular Methionine Depletion

open access: yesAdvanced Science, EarlyView.
Through modifying the switchable µ‐oxo bridged FeIII‐porphyrins moiety and NADH mimics into a metal‐organic capsule, multiple responsive manners for O2 activation, chemical oxygenation and metabolic transformation have been demonstrated for upregulating intracellular methionine depletion and accumulation of methionine sulfoxide to achieve effective ...
Chunming Ma   +5 more
wiley   +1 more source

Photosensitivity reactions in the elderly population: questionnaire-based survey and literature review

open access: yesTherapeutics and Clinical Risk Management, 2019
Katarzyna Korzeniowska,1 Artur Cieślewicz,1 Ewa Chmara,1 Anna Jabłecka,1 Mariola Pawlaczyk2 1Department of Clinical Pharmacology, Poznan University of Medical Sciences, Poznań 61-848, Poland; 2Department of Geriatric Medicine and Gerontology, Poznan ...
Korzeniowska K   +4 more
doaj  

High intensity ultraviolet radiation induced changes in aquatic arthropod with retene and riboflavin

open access: yesEnvironment Conservation Journal, 2011
Ozone depletion is resulting into increase in ultraviolet radiation level in the world. Exposure to UV radiation has been found to have negative effects on aquatic and terrestrial organisms.
Sunil Kumar, Priyanka Kumari
doaj   +1 more source

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