Results 111 to 120 of about 6,711 (234)

Synthesis and in vitro phototoxicity of novel π-extension derivatives of chlorin e6

open access: yes, 2017
32-Aryl substitution generated the maximum wavelength redshift and increased the in vitro phototoxicity against HepG2 cells simultaneously.
Liu Wang   +5 more
core   +1 more source

Real‐Time Multicolor Fluorescence Microscopy via Cross‐Channel Acquisition and Deep‐Learning‐Based Inference

open access: yesAdvanced Intelligent Discovery, EarlyView.
Sequential multicolor fluorescence imaging in dynamic microsystems is constrained by acquisition speed and excitation dose. This study introduces a real‐time framework to reconstruct spectrally separated channels from reduced cross‐channel acquisitions (frames containing mixed spectral contributions).
Juan J. Huaroto   +3 more
wiley   +1 more source

Cell Segmentation Beyond 2D—A Review of the State‐of‐the‐Art

open access: yesAdvanced Intelligent Discovery, EarlyView.
Cell segmentation underpins many biological image analysis tasks, yet most deep learning methods remain limited to 2D despite the inherently 3D nature of cellular processes. This review surveys segmentation approaches beyond 2D, comparing 2.5D and fully 3D methods, analyzing 31 models and 32 volumetric datasets, and introducing a unified reference ...
Fabian Schmeisser   +6 more
wiley   +1 more source

Comparison of 5-ALA phototoxicity of medulloblastoma vs. glioma.

open access: yes, 2013
Phototoxicity of 5-ALA in medulloblastoma cell line D283 Med compared to glioblastoma cell line U373 MG after incubation time of 2 h. -values were calculated according to formula (4), 95% confidence intervals (CI) are given.
Christian Scheidle (294229)   +6 more
core   +1 more source

Iodination improves the phototoxicity of an amphiphilic porphyrin

open access: yes, 2016
International audienceHighlights• A novel tri-iodinated photosensitising porphyrin was designed and synthesized.• The presence of the iodine atom optimize the singlet oxygen generation compared to its non-halogenated analogue.• The phototoxicity
Dumoulin, Fabienne   +8 more
core   +1 more source

Protein Corona Prevents TiO2 Phototoxicity.

open access: yes, 2015
Background & aimTiO2 nanoparticles have generally low toxicity in the in vitro systems although some toxicity is expected to originate in the TiO2-associated photo-generated radical production, which can however be modulated by the radical trapping ...
Maja Garvas (755866)   +23 more
core   +1 more source

Photoactivated Platinum Complexes: Targeting Membrane Proteins and Organelles for Precision Cancer Therapy

open access: yesAngewandte Chemie, EarlyView.
This review highlights an emerging anticancer approach integrating platinum agents into photodynamic therapy (PDT) and photoactivated chemotherapy (PACT) systems, further augmented by cancer cell membrane‐ and organelle‐targeting. By directing photoactivated platinum complexes from nontargeted distribution to cancer cells or defined subcellular sites ...
Shu Chen   +3 more
wiley   +1 more source

Photosensitivity reactions in the elderly population: questionnaire-based survey and literature review

open access: yesTherapeutics and Clinical Risk Management, 2019
Katarzyna Korzeniowska,1 Artur Cieślewicz,1 Ewa Chmara,1 Anna Jabłecka,1 Mariola Pawlaczyk2 1Department of Clinical Pharmacology, Poznan University of Medical Sciences, Poznań 61-848, Poland; 2Department of Geriatric Medicine and Gerontology, Poznan ...
Korzeniowska K   +4 more
doaj  

Bergamot oil intended for topical use - attempts for a risk assessment of phototoxicity

open access: yes, 2005
Bergamot oil is a widely used aromatic ingredient, e.g. in food and cosmetics. Its use is often limited due to reported phototoxicity, usually attributed to bergapten content.The aim of this study was to clarify the differences in the phototoxicity of ...
Jirova,D.   +5 more
core  

Quantitative determination of the reduction of phototoxicity and photobleaching by controlled light exposure microscopy

open access: yes, 2008
Phototoxicity and photobleaching are major limitations in live-cell fluorescence microscopy. They are caused by fluorophores in an excited singlet or triplet state that generate singlet oxygen and other reactive oxygen species.
Manders, E.M.M.   +4 more
core   +1 more source

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