Results 111 to 120 of about 17,235 (261)

Voriconazole-induced lentiginosis in a child: a phototoxicity warning sign. [PDF]

open access: yesAn Bras Dermatol
Henríquez F   +5 more
europepmc   +1 more source

Two‐Photon Endomicroscopy for Image‐Guided Magnetic Micro‐Agents

open access: yesSmall, EarlyView.
Image‐guided manipulation of magnetic micro‐agents requires localized fluorescence feedback capable of resolving dynamic interactions in confined environments. This study introduces a two‐photon endomicroscopy platform for real‐time motion tracking, multicolor micro‐agent discrimination, and imaging through biological tissue.
Juan J. Huaroto   +3 more
wiley   +1 more source

Exploiting singlet fission in <i>para</i>-azaquinodimethane nanoaggregates with high energy triplets to trigger phototoxic reactive oxygen species. [PDF]

open access: yesChem Sci
Sorbelli E   +12 more
europepmc   +1 more source

The photoswitchable ABAMIs for the future regulation of GWT1 in a spatiotemporal level

open access: yesSmart Molecules, EarlyView.
The GWT1‐targeted azobenzene‐aminopyridine derivatives (ABAMIs), sensitive to the light at wavelengths from 365 to 520 nm, are separately developed as photochromic ligands to regulate bioactivity as well as the GWT1 functions. These molecules are smart tools in photopharmacological studies, giving an innovative method for understanding functional GWT1 ...
Qian Ding   +8 more
wiley   +1 more source

A lysosomal escape‐enabled endoplasmic reticulum‐targeting BODIPY photothermal agent for enhanced tumor ablation

open access: yesSmart Molecules, EarlyView.
To advance precision cancer therapy, we engineered ER‐BDP NPs, a self‐assembled nanomedicine designed for selective ER localization. By integrating organelle targeting with localized laser activation, this agent mediates precision‐guided tumor destruction in vitro and in vivo while reducing off‐target effects, effectively balancing therapeutic efficacy
Shaoyang Shi   +8 more
wiley   +1 more source

Photoactivated iridium(III) complexes drive pyroptosis–necroptosis synergy for multi‐network photoimmunotherapy of renal cell carcinoma

open access: yesSmart Molecules, EarlyView.
Photoactivated iridium(III) complexes trigger mitochondrial DNA leakage and Ca²⁺ efflux, simultaneously driving pyroptosis and necroptosis to synergistically enhance immunogenic cell death. This multi‐network cascade promotes dendritic cell maturation and CD8⁺ T cell activation, achieving potent photoimmunotherapy of renal cell carcinoma.
Xin Qin   +16 more
wiley   +1 more source

Photostabilized halocyanine for near‐infrared excited bimodal photothermal synergism and tumor‐targeted therapy

open access: yesSmart Molecules, EarlyView.
A series of halogenated organic small molecules were prepared by substituting hydrogen atoms in BC7 molecules with halogen atoms. These chemically modified derivatives displayed significantly improved stability, warming efficiency, and reactive oxygen species generation ability. BC7‐Br and BC7‐Cl showed remarkably enhanced therapeutic efficacy relative
Zongjin Qu   +10 more
wiley   +1 more source

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