Results 131 to 140 of about 6,711 (234)

Multimodal Imaging of Live Cells and Tumor Spheroids by a G‐Quadruplex DNA Selective Ru(II)Polypyridyl Probe

open access: yesChemistry – A European Journal, EarlyView.
Harnessing the light‑switch properties of Ru‑PDC3, we demonstrate that it binds to G‑quadruplex DNA within the nuclei of living cells where it can act as a probe for real‑time imaging or at higher concentrations/illumination it can act as photosensitizer inducing phototoxicity.
Karmel S. Gkika   +5 more
wiley   +1 more source

A shining starlet: Nematostella vectensis as a model for developmental, regenerative, and comparative biology

open access: yesDevelopmental Dynamics, EarlyView.
Abstract The sea anemone, Nematostella vectensis, has been used as a model organism in developmental biology studies for many years. This estuarine species has the notable capacity to regenerate its full body plan from small pieces throughout life. Nematostella have been described as having a great degree of cellular plasticity.
Patrick A. Lewis   +3 more
wiley   +1 more source

Advancing super‐resolution stimulated emission depletion microscopy with luminescent lanthanide nanocrystals

open access: yesFlexMat, EarlyView.
The state‐of‐the‐art research advances and its cutting‐edge application in super resolution stimulated emission depletion technology based on luminescent lanthanide nanocrystals. Abstract Stimulated emission depletion (STED) microscopy overcomes the diffraction limit to reveal subcellular structures beyond the reach of conventional optical methods ...
Yaqi Chen   +4 more
wiley   +1 more source

Sustainable plant‐leaf‐derived carbon dots with deep‐red emission enable 1‐min photodynamic therapy of tumors

open access: yesFlexMat, EarlyView.
In this study, plant‐derived carbon dots (CDs) were prepared using natural plant leaves as raw materials through solvothermal method. These CDs retain the porphyrin structure from chlorophyll and can simultaneously generate I and II types of reactive oxygen species. A 660 nm laser irradiation for only 1 min can achieve efficient photodynamic anti‐tumor
Renjing Chen   +13 more
wiley   +1 more source

Citrus Essential Oils in Food Safety and Health: Advances in AI‐Assisted Authentication, Antimicrobial Applications, Sustainable Extraction, and Regulatory Translation

open access: yesFood Safety and Health, EarlyView.
Citrus essential oils combine sustainable extraction, AI‐assisted authentication, multi‐omics profiling, antimicrobial activity, and regulatory safety to enhance food quality, detect adulteration, and promote consumer health, and support intelligent, sustainable food systems through innovative industrial applications and circular bioeconomy strategies.
Md. Hassan Bin Nabi   +7 more
wiley   +1 more source

A Semi‐Automated Microfluidic Platform Employing Machine Learning Analysis to Study Adhesion Kinetics in Acute Myeloid Leukemia

open access: yesMicroscopy Research and Technique, EarlyView.
We have developed a semi‐automated shear flow platform using bright‐field optics and a machine‐learning analysis algorithm to dissect tumor‐microenvironment interactions. The algorithm quantifies the extent of adhesion at the single‐cell level and delivers consistent results within minutes instead of hours, facilitating high‐throughput analysis ...
Driti Ashok   +7 more
wiley   +1 more source

Calibration‐Free Single‐Frame Super‐Resolution Fluorescence Microscopy

open access: yesLaser &Photonics Reviews, EarlyView.
A deep learning framework reconstructs super‐resolved fluorescence images from a single dense camera frame, without any prior calibration or knowledge of the microscope. Trained solely on synthetic data, it generalizes across imaging setups and conditions.
Anežka Dostálová   +3 more
wiley   +1 more source

Optical Stimulation and Monitoring of the Peripheral Nervous System: Perspectives and Challenges Toward Clinical Translation

open access: yesLaser &Photonics Reviews, EarlyView.
Optical neuromodulation with IR light allows stimulation of the PNS without the need for physical contact with the target nerve or without requiring any genetic modification. The clinical translation of this technique will pave the way to the development of neural interfaces for restoring sensory feedback in individuals with limb amputation.
Federica Piccirillo   +20 more
wiley   +1 more source

Development and Characterization of Liposomes Containing a Zn(II) Porphyrin Derivative for the Application of Photodynamic Therapy in the Treatment of Breast Cancer

open access: yesLasers in Surgery and Medicine, EarlyView.
ABSTRACT Objectives This study aims to synthesize and characterize lipid nanosystems (liposomes) for the incorporation of a Zn(II) porphyrin derivative, Zn(II) meso‐tetrakis(N‐n‐hexylpyridinium‐2‐yl)porphyrin (ZnTnHex‐2‐PyP4+, ZnPH), intending to employ an alternative method of treatment, such as photodynamic therapy (PDT), for breast cancer (BC ...
Kammila Martins Nicolau Costa   +5 more
wiley   +1 more source

SHP2 in Cancer: From Tumor Biology to Therapeutic Targeting

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT SHP2 is a tyrosine phosphatase that mediates intracellular signaling downstream of transmembrane receptors regulated by a pair of src homology 2 (SH2) domains. Its overexpression and mutation are pivotal in driving tumor progression by influencing various cancer's fundamental characteristics, such as metastasis, DNA repair, angiogenesis ...
Maryam Jama   +2 more
wiley   +1 more source

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