Results 31 to 40 of about 34,272 (324)

Photosensitivity Reactions Induced by Photochemical Degradation of Drugs [PDF]

Advanced Pharmaceutical Bulletin, 2022
Photochemical degradation of drugs can lead to degradation products with potential toxic or allergizing effects for the human body. A significant amount of work has been carried out over the past few decades to clarify the molecular mechanism of ...
Hajnal Klelemen, Gabriel Hancu, Edina Kacsó, Lajos-Attila Papp   +3 more
doaj   +1 more source

Images in cardiovascular medicine : multiphoton microscopy for three-dimensional imaging of lymphocyte recruitment into apolipoprotein-E-deficient mouse carotid artery [PDF]

, 2007
Two recent elegant studies have shown that in apolipoprotein-E– deficient mice, the lamina adventitia is a major site of arterial wall inflammation associated with lymphocyte infiltration into atherosclerotic arteries and with formation of adventitial ...
Baker, Andrew H., Brewer, James M., Garside, Paul, Ialenti, Armando, Kennedy, Simon, Maffia, Pasquale, McInnes, Iain B., Zinselmeyer, Bernd H.   +7 more
core   +1 more source

Diazido mixed-amine platinum(IV) anticancer complexes activatable by visible-light form novel DNA adducts [PDF]

, 2013
Platinum diam(m)ine complexes, such as cisplatin, are successful anticancer drugs, but suffer from problems of resistance and side-effects. Photoactivatable PtIV prodrugs offer the potential of targeted drug release and new mechanisms of action.
Bancroft, Brabec, Brabec, Brabec, Butler, Caradonna, Coluccia, Dhara, Eastman, Eastman, Farrell, Farrer, Farrer, Fichtinger-Schepman, Guddneppanavar, Hall, Hamers, Harper, Intini, Jamieson, Kasparkova, Kasparkova, Kauffman, Keck, Kelland, Lau, Lemaire, Mackay, Mackay, Mackay, Najajreh, Ohndorf, O’Dwyer, Pantoja, Phillips, Pracharova, Pregosin, Prokop, Reedijk, Ronconi, Salassa, Salassa, Salassa, Salassa, Siddik, Stehlíková, Still, Suchánková, Tai, Vinje, Vlček, Wang, Westendorf, Westendorf, Westendorf, Wong, Yao, Zenker   +57 more
core   +1 more source

EXPERIMENTAL TESTING OF AN IN VIVO METHOD OF PHOTOTOXICITY EVALUATION

Регуляторные исследования и экспертиза лекарственных средств, 2018
At present all new medicinal products and cosmetics that absorb medium-wavelength UVB, long-wavelength UVA, or visible light in the range 290–700 nm need to be tested for potential phototoxicity.
V. А. Vavilova, E. V. Shekunova, V. A. Kashkin, M. N. Makarova, V. G. Makarov, A. Ya. Khaymenov   +5 more
doaj   +1 more source

Sparse and Random Sampling Techniques for High-Resolution, Full-Field, BSS-Based Structural Dynamics Identification from Video

Sensors, 2020
Video-based techniques for identification of structural dynamics have the advantage that they are very inexpensive to deploy compared to conventional accelerometer or strain gauge techniques. When structural dynamics from video is accomplished using full-
Bridget Martinez, Andre Green, Moises Felipe Silva, Yongchao Yang, David Mascareñas   +4 more
doaj   +1 more source

The use of non-animal alternatives in the safety evaluations of cosmetics ingredients by the Scientific Committee on Consumer Safety (SCCS) [PDF]

, 2015
In Europe, the safety evaluation of cosmetics is based on the safety evaluation of each individual ingredient. Article 3 of the Cosmetics Regulation specifies that a cosmetic product made available on the market is to be safe for human health when used ...
Vinardell Martínez-Hidalgo, Ma. Pilar
core   +2 more sources

Menthol reduces phototoxicity pain in a mouse model of photodynamic therapy [PDF]

, 2018
Phototoxicity-induced pain is a major clinical problem triggered by light acting on photosensitising drugs or endogenous porphyrins, notably protoporphyrin IX (PpIX), an intermediary in heme biosynthesis.
Baptista-Hon, Daniel, Bull, Fiona, Dalgaty, Faith, Gallacher, Michael, Hales, Tim G., Ibbotson, Sally H., Wright, Lisa   +6 more
core   +3 more sources

Increased Level of α2,6-Sialylated Glycans on HaCaT Cells Induced by Titanium Dioxide Nanoparticles under UV Radiation

Nanomaterials, 2018
As one of the most widely used nanomaterials, the safety of nano-TiO2 for human beings has raised concern in recent years. Sialylation is an important glycosylation modification that plays a critical role in signal transduction, apoptosis, and tumor ...
Yuanyuan Ren, Xin Liu, Runqing Geng, Qunwei Lu, Rong Rao, Xi Tan, Xiangliang Yang, Wei Liu   +7 more
doaj   +1 more source

Edito of the special focus issue on Environmental Toxicity of Nanoparticles [PDF]

, 2010
“The main goal of this special focus issue is to introduce the main parameters that affect the potential ecotoxicity of nanoparticles and to describe the state of the art with a few selected examples of interaction of different nanoparticles...
Flahaut, Emmanuel
core   +1 more source

Photobleaching and phototoxicity of mitochondria in live cell fluorescent super-resolution microscopy

Mitochondrial Communications
Photobleaching and phototoxicity can induce detrimental effects on cell viability and compromise the integrity of collected data, particularly in studies utilizing super-resolution microscopes.
Chia-Hung Lee, Douglas C. Wallace, Peter J. Burke   +2 more
doaj   +1 more source