Results 81 to 90 of about 3,532 (155)
Multimodal Hox5 activity generates motor neuron diversity
Motor neurons (MNs) are the final output of circuits driving fundamental behaviors, such as respiration and locomotion. Hox proteins are essential in generating the MN diversity required for accomplishing these functions, but the transcriptional ...
Ritesh KC +5 more
doaj +1 more source
Neurochemical assessment of identified phrenic motor neurons via flow cytometry
Flow cytometry (FCM) utilizes high powered, laser‐based tools to perform multi‐parametric analyses on cell populations. Although FCM is routinely utilized in immunology and cancer biology fields, it is rarely used in the study of neurobiology. Here, we show a novel use of FCM to identify and isolate phrenic motor neurons, a small, but critical pool of ...
Brendan J. Dougherty +3 more
openaire +1 more source
Protein 4.1B contributes to the organization of peripheral myelinated axons.
Neurons are characterized by extremely long axons. This exceptional cell shape is likely to depend on multiple factors including interactions between the cytoskeleton and membrane proteins.
Carmen Cifuentes-Diaz +10 more
doaj +1 more source
Phrenic Motor Neuron Survival Below a Cervical Spinal Cord Injury
Cervical spinal injury (cSCI) severs descending brainstem projections to spinal respiratory motor neurons, paralyzing respiratory muscles caudal to injury. Spinal hemisection at C2 (C2Hx) has frequently been used as an experimental model of cSCI to study both spontaneous and induced functional recovery of respiratory and non‐respiratory somatic motor ...
Ashley Erin Holland +6 more
openaire +1 more source
Distribution of Ipsilateral and Contralateral Glutamatergic Synaptic Inputs to Phrenic Motor Neurons
Excitatory descending glutamatergic (Glu) synaptic input to phrenic motor neurons (PhMNs) emanates from the ventrolateral medulla and is responsible for inspiratory drive and a range of higher force behaviors. Disruption of this excitatory input following unilateral C2 hemisection (C2SH) results in cessation of inspiratory‐related diaphragm muscle ...
Sabhya Rana +3 more
openaire +1 more source
Phrenic nerve transfer is a major dynamic treatment used to repair brachial plexus root avulsion. We analyzed 72 relevant articles on phrenic nerve transfer to repair injured brachial plexus that were indexed by Science Citation Index.
Ying Liu +5 more
doaj +1 more source
Background Transcranial magnetic stimulation (TMS), a non-invasive method of electrically stimulating neurons in the cerebral cortex, can change neuronal and cortical activity locally and remotely by applying localized magnetic fields. TMS can be used to
Hanan Mohamed Ibrahim Elshoura +2 more
doaj +1 more source
Background and Objectives: Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by the degeneration of both upper and lower motor neurons, leading to the rapid decline of motor function.
Ovidijus Laucius +5 more
doaj +1 more source
Cervical spinal cord hemisection impacts sigh and the respiratory reset in male rats
Cervical spinal cord injury impacts ventilatory and non‐ventilatory functions of the diaphragm muscle (DIAm) and contributes to clinical morbidity and mortality in the afflicted population.
Matthew J. Fogarty +3 more
doaj +1 more source

