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Utility of various genome lengths in diversity and evolution analyses of Hepatitis E virus. [PDF]
Hakze-van der Honing RW +3 more
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Rapid expansion of genotype D1.1 A(H5N1) influenza viruses in wild birds across North America during the 2024 migratory season. [PDF]
Harrington WN +42 more
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Case-control and genomic epidemiology characterization of SARS-CoV-2 breakthrough infections during the Delta-to-Omicron transition. [PDF]
Yuan E +15 more
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Update on the Phylodynamics of SADS-CoV [PDF]
Coronaviruses are known to be harmful and heterogeneous viruses, able to infect a large number of hosts. Among them, SADS-CoV (Swine Acute Diarrhea Syndrome Coronavirus), also known as PEAV (Porcine Enteric Alphacoronavirus), or SeA-CoV (Swine Enteric Alphacoronavirus), is the most recent Alphacoronavirus discovered, and caused several outbreaks ...
Pier Luigi Fiori +2 more
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Phylodynamics for cell biologists
Science, 2021Ancestry and evolution in cell biology Advances in experimental approaches for single-cell analysis allow in situ sequencing, genomic barcoding, and mapping of cell lineages within tissues and organisms. Large amounts of data have thus accumulated and present an analytical challenge.
T. Stadler, O. G. Pybus, M. P. H. Stumpf
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Development of Phylodynamic Methods for Bacterial Pathogens
Trends in Microbiology, 2021Phylodynamic methods have been essential to understand the interplay between the evolution and epidemiology of infectious diseases. To date, the field has centered on viruses. Bacterial pathogens are seldom analyzed under such phylodynamic frameworks, due to their complex genome evolution and, until recently, a paucity of whole-genome sequence data ...
Danielle J. Ingle +2 more
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Modelling tree shape and structure in viral phylodynamics [PDF]
Abstract Epidemiological models have highlighted the importance of population structure in the transmission dynamics of infectious diseases. Using HIV-1 as an example of a model evolutionary system, we consider how population structure affects the shape and the structure of a viral phylogeny in the absence of strong selection at the ...
Erik Volz, Simon Frost
exaly +3 more sources
Maximum Likelihood Phylodynamic Analysis
2018Die Anzahl der verfügbaren Genomsequenzen für verschiedene Pathogene hat in den letzten Jahren ausserordentlich zugenommen. Bestehende tradi- tionelle Methoden für die phylodynamische Analyse sind nicht effizient für eine große Anzahl von Sequenzen. Um mit den heute verfügbaren Daten- sätzen umzugehen, sind effiziente Heuristiken notwendig.
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Phylodynamics of Human Coxsackievirus B5
Future Virology, 2014ABSTRACT: Aim: Coxsackievirus B5 is recognized as an important pathogen in aseptic meningitis and hand, foot and mouth disease of children. A new distinctive sublineage of Coxsackievirus B5 associated with outbreak of neurological hand, foot and mouth disease in China was recently reported. Materials & methods: We employed a molecular evolution method
Congjun Hao +4 more
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Phylodynamics of Influenza A Viruses
2015Human populations are constantly exposed to emerging pathogens such as influenza A viruses that result from cross-species transmissions. Generally these sporadic events are evolutionary dead-ends, but occasionally, viruses establish themselves in a new host that offers a novel genomic context to which the virus must adjust to avoid attenuation. However,
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