Results 41 to 50 of about 2,036 (163)

Recent advances in computational phylodynamics

open access: yesCurrent Opinion in Virology, 2018
Time-stamped, trait-annotated phylogenetic trees built from virus genome data are increasingly used for outbreak investigation and monitoring ongoing epidemics. This routinely involves reconstructing the spatial and demographic processes from large data sets to help unveil the patterns and drivers of virus spread.
Baele, Guy   +4 more
openaire   +4 more sources

Tuberculosis outbreak investigation using phylodynamic analysis

open access: yesEpidemics, 2018
The fast evolution of pathogenic viruses has allowed for the development of phylodynamic approaches that extract information about the epidemiological characteristics of viral genomes. Thanks to advances in whole genome sequencing, they can be applied to slowly evolving bacterial pathogens like Mycobacterium tuberculosis.
Kühnert, Denise   +7 more
openaire   +9 more sources

Molecular Epidemiology of HIV-1 Subtype B Infection across Florida Reveals Few Large Superclusters with Metropolitan Origin

open access: yesMicrobiology Spectrum, 2022
Florida is considered an epicenter of HIV in the United States. The U.S. federal plan for Ending the HIV Epidemic (EHE) within 10 years prioritizes seven of Florida’s 67 counties for intervention. We applied molecular epidemiology methods to characterize
Shannan N. Rich   +7 more
doaj   +1 more source

Diverse Large HIV-1 Non-subtype B Clusters Are Spreading Among Men Who Have Sex With Men in Spain

open access: yesFrontiers in Microbiology, 2019
In Western Europe, the HIV-1 epidemic among men who have sex with men (MSM) is dominated by subtype B. However, recently, other genetic forms have been reported to circulate in this population, as evidenced by their grouping in clusters predominantly ...
Elena Delgado   +91 more
doaj   +1 more source

The Omicron Lineages BA.1 and BA.2 (Betacoronavirus SARS-CoV-2) Have Repeatedly Entered Brazil through a Single Dispersal Hub

open access: yesViruses, 2023
Brazil currently ranks second in absolute deaths by COVID-19, even though most of its population has completed the vaccination protocol. With the introduction of Omicron in late 2021, the number of COVID-19 cases soared once again in the country.
Alessandra P. Lamarca   +42 more
doaj   +1 more source

A Large-Scale Outbreak of Echovirus 30 in Gansu Province of China in 2015 and Its Phylodynamic Characterization

open access: yesFrontiers in Microbiology, 2020
BackgroundEchovirus 30 (E-30) has been investigated and reported worldwide and is closely associated with several infectious diseases, including encephalitis; myocarditis; and hand, foot, and mouth disease.
Jianhua Chen   +7 more
doaj   +1 more source

Phylogeography as a Proxy for Population Connectivity for Spatial Modeling of Foot-and-Mouth Disease Outbreaks in Vietnam

open access: yesViruses, 2023
Bayesian space–time regression models are helpful tools to describe and predict the distribution of infectious disease outbreaks and to delineate high-risk areas for disease control.
Umanga Gunasekara   +7 more
doaj   +1 more source

Discovering the Phylodynamics of RNA Viruses

open access: yesPLoS Computational Biology, 2009
1 Center for Infectious Disease Dynamics, Department of Biology, The Pennsylvania State University, Mueller Laboratory, University Park, Pennsylvania, United States of America, 2 Fogarty International Center, National Institutes of Health, Bethesda, Maryland, United States of America, 3 Department of Ecology and Evolutionary Biology and Woodrow Wilson ...
Edward C Holmes, Bryan T Grenfell
openaire   +4 more sources

ReMASTER: improved phylodynamic simulation for BEAST 2.7

open access: yesBioinformatics, 2023
Abstract Summary Phylodynamic models link phylogenetic trees to biologically-relevant parameters such as speciation and extinction rates (macroevolution), effective population sizes and migration rates (ecology and phylogeography), and transmission and removal/recovery rates (epidemiology) to ...
openaire   +2 more sources

Viruses Previously Identified in Brazil as Belonging to HIV-1 CRF72_BF1 Represent Two Closely Related Circulating Recombinant Forms, One of Which, Designated CRF122_BF1, Is Also Circulating in Spain

open access: yesFrontiers in Microbiology, 2022
Circulating recombinant forms (CRFs) are important components of the HIV-1 pandemic. Those derived from recombination between subtype B and subsubtype F1, with 18 reported, most of them of South American origin, are among the most diverse. In this study,
Javier E. Cañada-García   +14 more
doaj   +1 more source

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