Results 41 to 50 of about 2,682 (195)

Eight challenges in phylodynamic inference

open access: yesEpidemics, 2015
Epidemics ...
Frost, Simon D.W.   +5 more
openaire   +5 more sources

Characterizing the Countrywide Epidemic Spread of Influenza A(H1N1)pdm09 Virus in Kenya between 2009 and 2018

open access: yesViruses, 2021
The spatiotemporal patterns of spread of influenza A(H1N1)pdm09 viruses on a countrywide scale are unclear in many tropical/subtropical regions mainly because spatiotemporally representative sequence data are lacking. We isolated, sequenced, and analyzed
D. Collins Owuor   +13 more
doaj   +1 more source

Diverse Large HIV-1 Non-subtype B Clusters Are Spreading Among Men Who Have Sex With Men in Spain

open access: yesFrontiers in Microbiology, 2019
In Western Europe, the HIV-1 epidemic among men who have sex with men (MSM) is dominated by subtype B. However, recently, other genetic forms have been reported to circulate in this population, as evidenced by their grouping in clusters predominantly ...
Elena Delgado   +91 more
doaj   +1 more source

An efficient Bayesian inference framework for coalescent-based nonparametric phylodynamics [PDF]

open access: yes, 2015
MotivationThe field of phylodynamics focuses on the problem of reconstructing population size dynamics over time using current genetic samples taken from the population of interest. This technique has been extensively used in many areas of biology but is
Shahbaba, Babak   +6 more
core   +1 more source

Emerging Concepts of Data Integration in Pathogen Phylodynamics [PDF]

open access: yesSystematic Biology, 2016
Phylodynamics has become an increasingly popular statistical framework to extract evolutionary and epidemiological information from pathogen genomes. By harnessing such information, epidemiologists aim to shed light on the spatio-temporal patterns of spread and to test hypotheses about the underlying interaction of evolutionary and ecological dynamics ...
Baele, Guy   +3 more
openaire   +7 more sources

Phylogenetic Reconstructions Reveal the Circulation of a Novel Dengue Virus-1V Clade and the Persistence of a Dengue Virus-2 III Genotype in Northeast Brazil

open access: yesViruses, 2023
Dengue fever is among the most significant public health concerns in Brazil. To date, the highest number of Dengue notifications in the Americas has been reported in Brazil, with cases accounting for a total number of 3,418,796 reported cases as of mid ...
Hegger Fritsch   +20 more
doaj   +1 more source

Phylodynamic Inference for Structured Epidemiological Models

open access: yesPLoS Computational Biology, 2014
Coalescent theory is routinely used to estimate past population dynamics and demographic parameters from genealogies. While early work in coalescent theory only considered simple demographic models, advances in theory have allowed for increasingly complex demographic scenarios to be considered.
David A. Rasmussen   +2 more
openaire   +3 more sources

Whole genome sequencing reveals local transmission patterns of mycobacterium bovis in sympatric cattle and badger populations [PDF]

open access: yes, 2012
Whole genome sequencing (WGS) technology holds great promise as a tool for the forensic epidemiology of bacterial pathogens. It is likely to be particularly useful for studying the transmission dynamics of an observed epidemic involving a largely ...
O'Hare, Anthony   +53 more
core   +1 more source

Spatial phylodynamics of HIV-1 epidemic emergence in east Africa

open access: yes, 2009
DESIGN: We sought to investigate the evolutionary and historical reasons for the different epidemiological patterns of HIV-1 in the early epidemic. In order to characterize the demographic history of HIV-1 subtypes A and D in east Africa, we examined ...
Gray, R.H.   +35 more
core   +2 more sources

Phylodynamics beyond neutrality: the impact of incomplete purifying selection on viral phylogenies and inference [PDF]

open access: yesPhilosophical Transactions of the Royal Society B: Biological Sciences
Katia Koelle, David A Rasmussen
exaly   +2 more sources

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