Results 81 to 90 of about 2,113,711 (315)

The Future of Systematics: Tree-Thinking Without the Tree [PDF]

, 2012
Phylogenetic trees are meant to represent the genealogical history of life and apparently derive their justification from the existence of the tree of life and the fact that evolutionary processes are tree-like.
Velasco, Joel D.
core   +2 more sources

Lipid Droplet‐Localized Spindle Apparatus Coiled‐Coil Protein 1 Regulates Lipid Droplet Distribution

Advanced Science, EarlyView.
SPDL1‐L, a long isoform of SPDL1, is identified as a bona fide lipid droplet‐associated protein that acts as a dynein adaptor to drive perinuclear clustering of lipid droplets. By linking lipid droplets to the microtubule network, SPDL1‐L extends the function of SPDL1 beyond mitosis and contributes to lipid droplet organization and nuclear remodeling ...
Honggang Su, Huimin Pan, Yaqiang Liu, Wei Wang, Yang Jiao, Yumo Hang, Xiahe Huang, Yong E. Zhang, Yuhang Chen, Mei Ding, Xun Huang   +10 more
wiley   +1 more source

PTree: pattern-based, stochastic search for maximum parsimony phylogenies [PDF]

PeerJ, 2013
Phylogenetic reconstruction is vital to analyzing the evolutionary relationship of genes within and across populations of different species. Nowadays, with next generation sequencing technologies producing sets comprising thousands of sequences, robust ...
Ivan Gregor, Lars Steinbrück, Alice C. McHardy   +2 more
doaj   +2 more sources

Nanoparticle Adjuvant Design Enhances Germinal Center Responses Targeting Conserved Subdominant Epitopes for Pan‐Coronavirus Vaccine Development

Advanced Science, EarlyView.
Current SARS‐CoV‐2 vaccines generate short‐lived, strain‐specific immunity. A polymeric TLR7 agonist nanoparticle (TLR7‐NP) adjuvant enhances lymph node targeting and promotes early and sustained germinal center responses toward conserved S2 epitopes of the spike protein.
Sijin Huang, Kanella M. Cohen, Liqiang Chen, Xiaowo Kang, Chang Liu, Megan E. Demouth, Wenxia Jiang, Alexander R. Maldeney, Rong Tong, Zunlong Ke, Kartik Chandran, Wei Luo, Qian Yin   +12 more
wiley   +1 more source

Spatial Phylogenetics of Florida Vascular Plants: The Effects of Calibration and Uncertainty on Diversity Estimates

iScience, 2019
Summary: Recent availability of biodiversity data resources has enabled an unprecedented ability to estimate phylogenetically based biodiversity metrics over broad scales.
Julie M. Allen, Charlotte C. Germain-Aubrey, Narayani Barve, Kurt M. Neubig, Lucas C. Majure, Shawn W. Laffan, Brent D. Mishler, Hannah L. Owens, Stephen A. Smith, W. Mark Whitten, J. Richard Abbott, Douglas E. Soltis, Robert Guralnick, Pamela S. Soltis   +13 more
doaj   +1 more source

Plant DNA barcodes and assessment of phylogenetic community structure of a tropical mixed dipterocarp forest in Brunei Darussalam (Borneo). [PDF]

PLoS ONE, 2017
DNA barcoding is a fast and reliable tool to assess and monitor biodiversity and, via community phylogenetics, to investigate ecological and evolutionary processes that may be responsible for the community structure of forests.
Jacqueline Heckenhauer, Kamariah Abu Salim, Mark W Chase, Kyle G Dexter, R Toby Pennington, Sylvester Tan, Maria Ellen Kaye, Rosabelle Samuel   +7 more
doaj   +1 more source

Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors

Advanced Science, EarlyView.
This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su, Tianqing Nie, Guofeng Chen, Muya Xiong, Yumin Zhang, Guoqing Wu, Mengyuan You, Hang Xie, Jian He, Yanchao Xiong, Hangchen Hu, Wenfeng Zhao, Minjun Li, Gengfu Xiao, Leike Zhang, Yechun Xu   +15 more
wiley   +1 more source

Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation

Human Mutation, 2009
Human mitochondrial DNA is widely used as tool in many fields including evolutionary anthropology and population history, medical genetics, genetic genealogy, and forensic science.
M. van Oven, M. Kayser
semanticscholar   +1 more source

Coupling Nitrogenous Organic Wastewater Treatment and Biorefinery via N‐Cycling Bacterium

Advanced Science, EarlyView.
The vast reservoir of nitrogenous organic pollutants in industrial wastewaters can serve as untapped carbon‐nitrogen resources. This study employs the newly discovered Paracoccus sp. ZQW‐1 as a versatile chassis to simultaneously achieve N‐methylpyrrolidone (NMP) wastewater depuration and polyhydroxybutyrate (PHB) synthesis.
Ziqian Wang, Chunyu Du, Guanyu Zheng, Dahu Ding   +3 more
wiley   +1 more source

Visualising very large phylogenetic trees in three dimensional hyperbolic space

BMC Bioinformatics, 2004
Background Common existing phylogenetic tree visualisation tools are not able to display readable trees with more than a few thousand nodes. These existing methodologies are based in two dimensional space.
Liberles David A, Hyun Young, Hughes Timothy   +2 more
doaj   +1 more source