Results 51 to 60 of about 610,171 (266)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

APRECIEREA PARAMETRILOR DE CALITATE ȘI SIGURANȚĂ LA CARNEA DE PASĂRE REFRIGERATĂ, REALIZATĂ ÎN CONSUMUL PUBLIC

open access: yesAgricultural Science, 2023
The study assessed the quality and safety parameters of poultry meat from two local producers. Broiler chicken carcasses, refrigerated and packed in polyethylene, were collected from the marketing network for laboratory evaluations at the Republican ...
Alisa PÎRLOG
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Effects of Biochar on Container Substrate Properties and Growth of Plants—A Review

open access: yesHorticulturae, 2019
Biochar refers to a processed, carbon-rich material made from biomass. This article provides a brief summary on the effects of biochar on container substrate properties and plant growth.
Lan Huang, Mengmeng Gu
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Synthesis, physical and chemical properties of 2-((5-(hydroxy(phenyl)methyl)-4R-4H-1,2,4-triazole-3-yl)thio)acetic acids and its salts

open access: yesZaporožskij Medicinskij Žurnal, 2018
Today’s a creation of new domestic medicines is very important problem for pharmacy and medicine. Therefore, it is relevant to synthesize new domestic biologically active compounds. It is known that a large number of new 3-thio and 4-amino derivatives
A. M. Rud   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Phenolic profiles and antioxidant activity of Morus alba L. infusions prepared from commercially available products and naturally collected leaves

open access: yesScientific Reports
The aim of this study was to compare the phenolic compound content and antioxidant activity of infusions made from commercially available Morus alba L. leaves with those of infusions made from a naturally collected source.
Michał Adam Janiak   +7 more
doaj   +1 more source

Analysis of Reverse Osmosis Separation Performances of Ethanol/Water Mixtures and Design of Ethanol Concentration Processes

open access: yesJournal of Chemical Engineering of Japan
This study successfully analyzed the reverse osmosis (RO) separation performances of ethanol/water mixture (1–37 wt% of ethanol) with polymeric RO membranes using transport equations derived on the basis of the solution-diffusion mechanism in which the ...
Kazuki Akamatsu   +3 more
doaj   +1 more source

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