Results 51 to 60 of about 2,185,082 (309)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Silazane elastomer remains resilient at 400 deg C [PDF]

, 1966
Smooth, unfoamed elastomer is unaffected by common acids, alkalies, and organic solvents.

core   +1 more source

Synthesis, physical and chemical properties of 2-((5-(hydroxy(phenyl)methyl)-4R-4H-1,2,4-triazole-3-yl)thio)acetic acids and its salts

Zaporožskij Medicinskij Žurnal, 2018
Today’s a creation of new domestic medicines is very important problem for pharmacy and medicine. Therefore, it is relevant to synthesize new domestic biologically active compounds. It is known that a large number of new 3-thio and 4-amino derivatives
A. M. Rud, A. G. Kaplaushenko, I. O. Yurchenko   +2 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Phenolic profiles and antioxidant activity of Morus alba L. infusions prepared from commercially available products and naturally collected leaves

Scientific Reports
The aim of this study was to compare the phenolic compound content and antioxidant activity of infusions made from commercially available Morus alba L. leaves with those of infusions made from a naturally collected source.
Michał Adam Janiak, Anna Gryn-Rynko, Katarzyna Sulewska, Ryszard Amarowicz, Kamila Penkacik, Radomir Graczyk, Dorota Olszewska-Słonina, Michał Stanisław Majewski   +7 more
doaj   +1 more source

The Effect of Pretreatment by using Electron Beam Irradiation on Oil Palm Empty Fruit Bunch

Atom Indonesia, 2016
Oil palm empty fruit bunch (OPEFB) is a potential type of lignocellulosic biomass for second-generation bioethanol production. The pretreatment process is an important process in the series of processes to produce bioethanol.
A. Kristiani, N. Effendi, D. Styarini, F. Aulia, Y. Sudiyani   +4 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Analysis of Reverse Osmosis Separation Performances of Ethanol/Water Mixtures and Design of Ethanol Concentration Processes

Journal of Chemical Engineering of Japan
This study successfully analyzed the reverse osmosis (RO) separation performances of ethanol/water mixture (1–37 wt% of ethanol) with polymeric RO membranes using transport equations derived on the basis of the solution-diffusion mechanism in which the ...
Kazuki Akamatsu, Tomonori Kimura, Shigeo Oba, Shin-ichi Nakao   +3 more
doaj   +1 more source

Some compositional characteristics of capers (Capparis spp,) seed and oil

Grasas y Aceites, 1999
Capparis spinosa L. var. spinosa and Capparis ovata Desf. var. canescens seeds were evaluated for weight, sizes, moisture, ash, crude protein, crude oil, energy and crude fiber.
Attila Akgül, Musa Özcan
doaj   +1 more source