The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
A class of symmetric-hyperbolic PDEs modelling fluid and solid continua*** [PDF]
ESAIM: Proceedings and SurveysWe generalize a new symmetric-hyperbolic system of PDEs proposed in [ESAIM:M2AN 55 (2021) 807-831] for Maxwell fluids to a class of systems that define unequivocally multi-dimensional visco-elastic flows. Precisely, within a general setting for continuum
Boyaval Sébastien
doaj +1 more source
Evaluating the economic impact of water scarcity in a changing world
Nature Communications, 2021 The impacts of water scarcity depend on physical basin characteristics and global economic dynamics. Here, the authors show scenario assumptions can yield either highly positive or negative economic impacts due to water scarcity, and the drivers of these
Flannery Dolan +5 more
doaj +1 more source
Restoring the Physical Meaning of Metamaterial Constitutive Parameters
, 2010 Metamaterial homogenization is often based on implicit assumptions inspired to natural material models. Retrieved effective permittivity and permeability, however, are often non-physical, especially near the array resonances, of most interest for ...
Andrea Alù, L. Landau
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Unconditionally Secure and Universally Composable Commitments from Physical Assumptions [PDF]
, 2013 We present a constant-round unconditional black-box compiler that transforms any ideal (i.e., statistically-hiding and statistically-binding) straight-line extractable commitment scheme, into an extractable and equivocal commitment scheme, therefore yielding to UC-security [9].
Damgård, Ivan Bjerre +1 more
openaire +2 more sources
FIGHTING THE CLASSICAL CRIME-SCENE ASSUMPTIONS. CRITICAL ASPECTS IN ESTABLISHING THE CRIME-SCENE PERIMETER IN COMPUTER-BASED EVIDENCE CASES [PDF]
Challenges of the Knowledge Society, 2016 Physical-world forensic investigation has the luxury of being tied to the sciences governing the investigated space, hence some assumptions can be made with some degree of certainty when investigating a crime.
Cristina DRIGĂ, Svetlana PURICI
doaj
Closed Timelike Curves, Singularities and Causality: A Survey from Gödel to Chronological Protection
Universe, 2021 I give a historical survey of the discussions about the existence of closed timelike curves in general relativistic models of the universe, opening the physical possibility of time travel in the past, as first recognized by K.
Jean-Pierre Luminet
doaj +1 more source
New Theoretical Approach to Quantum Size Effects of Interactive Electron-hole in Spherical Semiconductor Quantum Dots [PDF]
, 2009 The issue of quantum size effects of interactive electron-hole systems in spherical semiconductor quantum dots is put to question. A sharper theoretical approach is suggested based on a new pseudo-potential method.
Billaud, Baptiste +2 more
core +3 more sources
Physics Breakthrough Disproves Fundamental Assumptions of the Chicago School
SSRN Electronic Journal, 2023 8 figures; 56 ...
openaire +2 more sources