Results 101 to 110 of about 7,644,829 (380)
Solute–Solvent Interactions in Modern Physical Organic Chemistry: Supramolecular Polymers as a Muse
Journal of the American Chemical Society, 2020 Interactions between solvents and solutes are a cornerstone of physical organic chemistry and have been the subject of investigations over the last century.
Mathijs F. J. Mabesoone +2 more
semanticscholar +1 more source
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
Molecular Oncology, EarlyView.We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi +26 more
wiley +1 more source
PRACTICAL PHYSICAL CHEMISTRY. [PDF]
Journal of the American Chemical Society, 1907 n ...
openaire +2 more sources
Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma
Molecular Oncology, EarlyView.This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu +15 more
wiley +1 more source
The cupric complexes of glycine and of alanine [PDF]
, 1932 The following report is the first of a projected series of studies of the physical chemistry of the compounds of the heavy metals, particularly of copper and of iron, with substances of biological importance. These studies are invited by the accumulation
Borsook, Henry, Thimann, Kenneth V.
core
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
Yakov Syrkin: On the 125th anniversary of his birthday
Тонкие химические технологии, 2019 The article is dedicated to the 125th birthday of Yakov Kivovich Syrkin - Academician, Doctor of Chemical Sciences, Professor, Laureate of the Stalin Prize, and founder of the school of quantum chemistry in Russia.
S. S. Plotkin +2 more
doaj +1 more source
The octet rule in chemical space: Generating virtual molecules [PDF]
, 2017 We present a generator of virtual molecules that selects valid chemistry on the basis of the octet rule. Also, we introduce a mesomer group key that allows a fast detection of duplicates in the generated structures. Compared to existing approaches, our model is simpler and faster, generates new chemistry and avoids invalid chemistry.
arxiv +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source