Results 51 to 60 of about 1,664,181 (312)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
PHYSICAL PROPERTIES OF SPECKLES [PDF]
, 1978 Speckles are no longer regarded merely as a noise element, but as a carrier of information to be used in different applications. This offers a powerful and simple tool for studying surface roughness, for measuring displacement and strain, and for deformation and vibration analysis.
openaire +3 more sources
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Polish Journal of Food and Nutrition Sciences, 2016 The antioxidant potential and phenolic compounds content were investigated in ten white bean varieties widely consumed in Turkey. Total phenolic contents of seeds varied between 0.33 and 0.63 mg GAE/g.
Orak Hakime Hülya +3 more
doaj +1 more source
Fuzzy modelling of prescribed burning effects on soil physical properties
, 2009 This paper presents the preliminary work of an approach where Fuzzy Boolean Nets (FBN) are being used to extract qualitative knowledge regarding the effect of prescribed fire burning on soil chemical physical properties.
Meira Castro, Ana C. +3 more
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
MetalsThe microstructure, phase composition, and high-temperature oxidation behavior of Al0.5CoCr0.5NiPt0.1 and AlCoCr0.5NiPt0.1 multi-principal element alloys (MPEAs) at 1100 °C in air were investigated.
Olga Samoilova +5 more
doaj +1 more source
Magnetoelectronic properties of graphene dressed by a high-frequency field
, 2016 Solving the Schrödinger problem for electrons in graphene subjected to both a stationary magnetic field and a strong high-frequency electromagnetic wave (dressing field), we found that the dressing field drastically changes the structure of Landau levels
Dini, K. +3 more
core +1 more source