Influence of Neutralization Precipitation Conditions on the Physical Stability of Amorphous Solid Pharmaceuticals [PDF]
MoleculesThis research focused on the precipitation of amorphous forms of nilotinib with high physical stability through the manipulation of various parameters in the neutralization reaction, specifically the quantity of nilotinib, the pH value, and the ...
Zhihui Yuan +4 more
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High-Pressure Dielectric Spectroscopic Studies of Amorphous CBD: Investigating Molecular Dynamics and Physical Stability Under Manufacturing Conditions of the Pharmaceuticals [PDF]
PharmaceuticsObjectives: This study highlighted the key role played by high-pressure (HP) dielectric spectroscopic measurements of amorphous CBD to probe the molecular dynamics in order to examine the physical stability of the drug.
Mariya Mathew +3 more
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Physical Stability and Molecular Mobility of Resveratrol in a Polyvinylpyrrolidone Matrix [PDF]
MoleculesThe physical stability, molecular mobility, and appearance of nanocrystalline resveratrol in a polyvinylpyrrolidone (PVP) matrix were investigated. Two formulations with resveratrol loadings of 30% and 50% were prepared and characterized using powder X ...
Aleksandra Pajzderska +4 more
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Investigation of the Influence of Anti-Solvent Precipitation Parameters on the Physical Stability of Amorphous Solids [PDF]
MoleculesAmorphous solids exhibit enhanced solubility and dissolution rates relative to their crystalline counterparts. However, attaining optimal bioavailability presents a challenge, primarily due to the need to maintain the physical stability of amorphous ...
Zunhua Li +3 more
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Gesture-Based Physical Stability Classification and Rehabilitation System [PDF]
SensorsThis paper introduces the Gesture-Based Physical Stability Classification and Rehabilitation System (GPSCRS), a low-cost, non-invasive solution for evaluating physical stability using an Arduino microcontroller and the DFRobot Gesture and Touch sensor ...
Sherif Tolba, Hazem Raafat, A. S. Tolba
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Binary Pea Protein–Psyllium Hydrogel: Insights into the Influence of pH and Ionic Strength on the Physical Stability and Mechanical Characteristics [PDF]
GelsFood hydrogels, used as delivery systems for bioactive compounds, can be formulated with various food-grade biopolymers. Their industrial utility is largely determined by their physicochemical properties.
Adonis Hilal +3 more
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Invariant representation of physical stability in the human brain [PDF]
eLife, 2022 Successful engagement with the world requires the ability to predict what will happen next. Here, we investigate how the brain makes a fundamental prediction about the physical world: whether the situation in front of us is stable, and hence likely to ...
RT Pramod +3 more
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An Investigation of the Impact of Precipitation Temperature and Filter Cake Thickness on the Physical Stability of Amorphous Solids: A Case Study [PDF]
MoleculesThe purpose of this study was to resolve the issue of physical instability in amorphous solid drugs, which can result in unwanted crystallization, affecting solubility and dissolution rates.
Zunhua Li +4 more
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ADMET and DMPK, 2023 Background and purpose: Physicochemical properties of an amorphous solid dispersion (ASD) comprising an experimental grade of hydroxypropyl methylcellulose acetate succinate (HPMCAS-MX) with lower glass transition temperature have been previously ...
Hironori Tanaka +2 more
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Journal of Pharmacy and Bioallied Sciences, 2021 Introduction: All-in-one parenteral nutrition (AIO-PN) is essential for patients with limited venous access, e.g. premature infants. So far, there are still some conflicting data related to the stability of AIO-PN. The aim of this study is to examine the
Suci Hanifah +3 more
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