Results 71 to 80 of about 2,959,833 (267)

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Maximum Angle of Stability of a Wet Granular Pile

open access: yes, 2005
Anyone who has built a sandcastle recognizes that the addition of liquid to granular materials increases their stability. However, measurements of this increased stability often conflict with theory and with each other [1-7].
A Samadani   +13 more
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Spectral stability of Prandtl boundary layers: an overview [PDF]

open access: yes, 2014
In this paper we show how the stability of Prandtl boundary layers is linked to the stability of shear flows in the incompressible Navier Stokes equations.
Grenier, Emmanuel   +2 more
core  

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Amorphous Solid Dispersion of Epigallocatechin Gallate for Enhanced Physical Stability and Controlled Release

open access: yesPharmaceuticals, 2017
Epigallocatechin gallate (EGCG) has been recognized as the most prominent green tea extract due to its healthy influences. The high instability and low bioavailability, however, strongly limit its utilization in food and drug industries.
Yizheng Cao, Jing Teng, Jon Selbo
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Overview geotechnical model tests on dike safety at Deltares [PDF]

open access: yes, 2012
Three on-going dike safety studies (on: macro stability, piping and flow slides) in the Netherlands make use of geotechnical physical models. A short outline of these projects is presented; the physical models chosen are described and discussed.
Bezuijen, Adam   +3 more
core   +1 more source

Focusing of Active Particles in a Converging Flow

open access: yes, 2017
We consider active particles swimming in a convergent fluid flow in a trapezoid nozzle with no-slip walls. We use mathematical modeling to analyze trajectories of these particles inside the nozzle.
Aranson, Igor   +3 more
core   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

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