Results 31 to 40 of about 104,105 (259)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Understanding Young Women’s Experiences of Barriers in High School Physics Education

open access: yesCanadian Journal for New Scholars in Education, 2020
This paper reports results of a qualitative study that aimed to understand how young women experience barriers in their high school physics education. The bases of the research include the longstanding issue of underrepresentation of women in physics in
Lindsay Mainhood
doaj  

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Combining Surveys and Sensors to Explore Student Behaviour

open access: yesEducation Sciences, 2020
Student belongingness is important for successful study paths, and group work forms an important part of modern university physics education. To study the group dynamics of introductory physics students at the University of Helsinki, we collected network
Inkeri Kontro, Mathieu Génois
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

ENTREVISTA CON EDWIN GERMAN GARCIA ARTEAGA [PDF]

open access: yesGondola, 2011
Brief biography: Degree in Physics Teaching at National Pedagogical University, Colombia. Master in Physics Teaching at the National Pedagogical University, Colombia.
OLGA LUCIA CASTIBLANCO ABRIL
doaj  

Primena računara u nastavi fizike / Computers in teaching physics

open access: yesVojnotehnički Glasnik, 2008
U radu je dat kratak osvrt na istraživanje nastave fizike, kao i na upotrebu novih tehnologija, tj. računara u nastavi fizike. Pri korišćenju računara neophodno je primeniti metodičke zahteve koji bi trebalo da budu ispoštovani pri izradi softvera ...
Nada Čitaković
doaj   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

open access: yesFEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso   +4 more
wiley   +1 more source

The ecosystem of e-learning model for higher education

open access: yesSouth African Journal of Science, 2019
We present the ecosystem of e-learning (EeL) model, which can be applied to any higher education context, and which takes full account of all inhabitants and their interrelationships, not only the components, of the e-learning food chain.
Valentino van de Heyde, André Siebrits
doaj   +1 more source

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