Results 81 to 90 of about 806,968 (339)

An endogenous crepuscular rhythm of rainbow trout (Salmo gairdneri) photomechanical movements [PDF]

open access: yes, 1982
1. The position of the epithelial pigment and cones in the retina of Salmo gairdneri was determined during extended periods of darkness in fish entrained to both artificial and natural light/dark cycles. 2. An endogenous rhythm of such photomechanical
Douglas, R. H.
core  

Solving the woolly mammoth conundrum: amino acid 15N-enrichment suggests a distinct forage or habitat [PDF]

open access: yes, 2015
Understanding woolly mammoth ecology is key to understanding Pleistocene community dynamics and evaluating the roles of human hunting and climate change in late Quaternary megafaunal extinctions. Previous isotopic studies of mammoths’ diet and physiology
Longstaffe, Fred J   +3 more
core   +2 more sources

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Did Going North Give Us Migraine? An Evolutionary Approach on Understanding Latitudinal Differences in Migraine Epidemiology [PDF]

open access: yes, 2019
This commentary discusses a recent publication by evolutionary biologists with strong implications for migraine experts. The Authors showed that a gene polymorphism associated with migraine gave our ancestors an evolutionary advantage when colonizing ...
Di Piero, V.   +3 more
core   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Ecological-biological Aspects of Stipa krylovii Roshev Adaptation at the Initial Stages of Ontogenesis [PDF]

open access: yesJournal of Stress Physiology & Biochemistry, 2016
Xerophytic cereal Stipa krylovii Roshev is interesting as a relic with extensive capabilities to adapt to severe climatic conditions of Eastern Zabaikal’ye, which allows it to occupy a vast areal.
N.S. Chistyakova   +2 more
doaj  

Evolution after Introduction of a Novel Metabolic Pathway Consistently Leads to Restoration of Wild-Type Physiology [PDF]

open access: yes, 2014
Organisms cope with physiological stressors through acclimatizing mechanisms in the short-term and adaptive mechanisms over evolutionary timescales. During adaptation to an environmental or genetic perturbation, beneficial mutations can generate numerous
Carroll, Sean, Marx, Christopher J
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

07 Intern Assignment Biological Adaptations [PDF]

open access: yes, 2020
WELCOME to WINDOWS on the INQUIRY CLASSROOM! You have landed on a piece of a National Science Foundation Project (DUE 1245730) directed by Professor Chris Bauer, Chemistry Department, University of New Hampshire.
Bauer, Christopher F.
core   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy