Results 11 to 20 of about 492,192 (286)

Glucocorticoid induced bone disorders in children: Research progress in treatment mechanisms

open access: yesFrontiers in Endocrinology, 2023
Long-term or supra-physiological dose of glucocorticoid (GC) application in clinic can lead to impaired bone growth and osteoporosis. The side effects of GC on the skeletal system are particularly serious in growing children, potentially causing growth ...
Junying Hua   +7 more
doaj   +1 more source

Side Effects of Human Drug Use: An Overview of the Consequences of Eels’ Exposure to Cocaine

open access: yesFishes, 2023
The widespread use of drugs is a global problem which affects not only humans but also the environment around them, as research is showing the presence of these substances in different environmental matrices, like air, water, and soil.
Luigi Rosati   +5 more
doaj   +1 more source

Peptides: Prospects for Use in the Treatment of COVID-19

open access: yesMolecules, 2020
There is a vast practice of using antimalarial drugs, RAS inhibitors, serine protease inhibitors, inhibitors of the RNA-dependent RNA polymerase of the virus and immunosuppressants for the treatment of the severe form of COVID-19, which often occurs in ...
Vladimir Khavinson   +4 more
doaj   +1 more source

The effects of estrogen on targeted cancer therapy drugs

open access: yesPharmacological Research, 2022
Improving the efficacy of anticancer drugs is especially challenging. Estrogen is a sex hormone that not only promotes the development of female secondary sexual characteristics, but also supports many important physiological functions.
Ying Zhao   +4 more
doaj   +1 more source

Circadian Effects of Drug Responses

open access: yesAnnual Review of Biomedical Engineering, 2021
Circadian rhythms describe physiological systems that repeat themselves with a cycle of approximately 24 h. Our understanding of the cellular and molecular origins of these oscillations has improved dramatically, allowing us to appreciate the significant
Y. Nahmias, I. Androulakis
semanticscholar   +1 more source

Anti-inflamatórios não esteroides: Efeitos cardiovasculares, cérebro-vasculares e renais Antiinflamatorios no esteroides: efectos cardiovasculares, cerebrovasculares y renales Nonsteroidal anti-inflammatory drugs: cardiovascular, cerebrovascular and renal effects

open access: yesArquivos Brasileiros de Cardiologia, 2010
Os anti-inflamatórios não esteroides (AINEs) encontram-se entre os medicamentos mais prescritos em todo o mundo. Essa classe heterogênea de fármacos inclui a aspirina e vários outros agentes inibidores da ciclo-oxigenase (COX), seletivos ou não. Os AINEs
Michel Batlouni
doaj   +1 more source

Nanodrugs alleviate acute kidney injury: Manipulate RONS at kidney

open access: yesBioactive Materials, 2023
Currently, there are no clinical drugs available to treat acute kidney injury (AKI). Given the high prevalence and high mortality rate of AKI, the development of drugs to effectively treat AKI is a huge unmet medical need and a research hotspot. Although
Qiaohui Chen   +11 more
doaj   +1 more source

Direct but no transgenerational effects of decitabine and vorinostat on male fertility. [PDF]

open access: yesPLoS ONE, 2015
Establishment and maintenance of the correct epigenetic code is essential for a plethora of physiological pathways and disturbed epigenetic patterns can provoke severe consequences, e.g. tumour formation.
Ruth Kläver   +10 more
doaj   +1 more source

Antidepressant behavioral effects of duloxetine and amitriptyline in the rat forced swimming test Efeitos antidepressivos da duloxetina e da amitriptilina no teste do nado forçado em ratos

open access: yesActa Cirúrgica Brasileira, 2008
PURPOSE: To compare the effects of the antidepressant drugs duloxetine and amitriptyline on depressive behaviors in rats. METHODS: Fifteen male Wistar rats were given systemic injections of duloxetine, amitriptyline or saline prior to a Forced Swimming ...
Honório Sampaio Menezes   +7 more
doaj   +1 more source

Antidepressant behavioral effects of duloxetine and fluoxetine in the rat forced swimming test Efeitos antidepressivos da duloxetina e da fluoxetina no teste do nado forçado em ratos

open access: yesActa Cirúrgica Brasileira, 2007
PURPOSE: To compare the effects of the antidepressant drugs duloxetine and fluoxetine on depressive behaviors in rodents. METHODS: Eighteen male Wistar rats were given systemic injections of duloxetine, fluoxetine, or saline prior to a Forced Swimming ...
Leandro Ciulla   +5 more
doaj   +1 more source

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